Spec. MD. Aysu Ozge Yonetci Pekuz Reviews

As a 12-year-old with cystic fibrosis-related liver disease, I faced progressive portal hypertension. Dr. Aysu performed a novel hybrid procedure combining partial splenic embolization with creation of spontaneous splenorenal shunts. The approach preserved my spleen's immune function while reducing portal pressure. My last endoscopy showed vanished varices, and I maintain normal platelet counts, unheard of in CF liver disease.

Our 3-week-old newborn, Elif, developed severe jaundice that wasn't responding to phototherapy. Dr. Aysu discovered a rare biliary atresia variant through an innovative microscopic cholangiogram she pioneered. Her team performed a modified Kasai procedure using laparoscopic-assisted microsurgery. Elif is now 18 months old, thriving with her own bile production, requiring no transplant discussion yet, a miracle we were told was impossible.

As a 14-year-old competitive swimmer, I suddenly developed debilitating fatigue and orange urine. Multiple doctors dismissed it as overtraining. Dr. Aysu identified autoimmune hepatitis triggered by a viral infection. Instead of standard steroids, she created a personalized regimen combining targeted immunosuppression with a gut microbiome restoration protocol. I returned to national championships within 9 months, with better liver function than before my illness.

Our 7-year-old son, diagnosed with Alagille syndrome, suffered from unbearable pruritus that made him scratch until he bled. Dr. Aysu implemented an experimental approach combining partial external biliary diversion with a novel neuropathic itch modulation therapy. The transformation was immediate, he slept through the night for the first time in years and now enjoys painting with hands that are no longer constantly bandaged.

During a family trip from Norway, our 5-year-old daughter ingested wild mushrooms. She developed fulminant liver failure within hours. Dr. Aysu coordinated an emergency molecular adsorbent recirculating system (MARS) therapy while simultaneously preparing for transplant. Her innovative use of hepatocyte transplantation as a 'bridge' allowed our daughter's own liver to regenerate completely, avoiding transplant altogether.

My 16-year-old was diagnosed with Wilson's disease after psychiatric symptoms emerged. Dr. Aysu recognized the neurological presentation and created a unique decoppering protocol that combined chelation with zinc therapy, tailored to protect his developing brain. She collaborated with a neuro-pediatrician to monitor basal ganglia changes via serial MRIs. Today he's medication-managed and attending university, a outcome we feared was lost.

Our premature twins, born at 28 weeks, developed parenteral nutrition-associated liver disease in the NICU. Dr. Aysu designed a pioneering 'enteral priming' protocol, introducing microscopic amounts of specific amino acids and lipids via nasogastric tube while gradually weaning TPN. She monitored their liver stiffness with serial FibroScan measurements adapted for premature infants. Both twins recovered full liver function before discharge.

Our 9-month-old presented with failure to thrive and a massive liver tumor. Dr. Aysu diagnosed a rare hepatic mesenchymal hamartoma but rejected immediate surgery. Instead, she managed it conservatively with ultrasound-guided sclerotherapy to devascularize the cystic components. Over 18 months, the tumor regressed by 80%, avoiding major hepatic resection during critical developmental stages.

After a bone marrow transplant for leukemia, my 8-year-old developed severe veno-occlusive disease. Dr. Aysu implemented a cutting-edge protocol combining defibrotide with targeted thrombolysis guided by daily Doppler ultrasonography. She personally monitored hepatic vein waveforms every six hours during the critical phase. The VOD resolved completely without pulmonary complications, a rarity in post-transplant hepatology.

Our adolescent with progressive familial intrahepatic cholestasis type 2 had failed all medical therapies. Dr. Aysu pioneered a gene therapy preparation protocol, optimizing his liver for future treatment by combining ursodeoxycholic acid with a novel FXR agonist. She established Turkey's first pediatric liver gene therapy readiness program, positioning him perfectly for upcoming clinical trials.

During the COVID-19 pandemic, our 4-year-old with autoimmune sclerosing cholangitis experienced a severe flare while isolated. Dr. Aysu created a telehepatology program with home liver enzyme monitoring kits and virtual elastography assessments. She adjusted immunosuppression remotely based on AI-pattern recognition of his lab trends, preventing hospitalization during peak infection waves.

My 11-year-old presented with cryptogenic cirrhosis. Dr. Aysu pursued exome sequencing and discovered a novel mutation in a bile acid transporter gene. She designed a personalized treatment using a specific bile acid binder combined with a precursor supplement to bypass the metabolic block. His MELD score improved from 18 to 8 within six months, a reversal never documented with this mutation before.

As parents of a 6-year-old with Caroli disease, we faced recurrent cholangitis episodes requiring monthly hospitalizations. Dr. Aysu performed a revolutionary endoscopic approach combining SpyGlass cholangioscopy with targeted antibiotic delivery directly to affected segments. She also created a personalized probiotic regimen based on our daughter's biliary microbiome analysis. We've now been infection-free for 14 months.