Patient Experience
A 22-year-old music student with Marfan syndrome presented with sudden chest pain. While aortic dissection was ruled out, Dr. Sagcan diagnosed spontaneous pneumomediastinum from repeated Valsalva during instrument practice. Conservative management with oxygen and analgesia was successful. The patient's conservatory adjusted his performance requirements during the 3-week recovery.
A 63-year-old retired ballet master presented with joint pain and rash, initially diagnosed with rheumatoid arthritis. Dr. Sagcan recognized the photosensitive distribution and ordered angiographic studies, diagnosing cholesterol embolization syndrome after cardiac catheterization. Treatment involved statins and corticosteroids. His former students organized a rotating care schedule during his 5-month recovery.
A 72-year-old retired ship captain from the Black Sea region, lifelong smoker with no prior hospitalizations, presented with 3 weeks of progressive fatigue and unexplained weight loss. Dr. Sagcan discovered subtle clubbing and ordered a CT scan revealing a rare thymic carcinoma with paraneoplastic syndrome. Treatment involved immunotherapy instead of standard chemotherapy due to the patient's specific biomarkers. Recovery was slow but steady over 8 months, with his grandchildren's weekly video calls providing crucial emotional support.
A 19-year-old university exchange student from Kazakhstan developed sudden high fever, headache, and confusion after arriving in Istanbul. Dr. Sagcan recognized the temporal connection to her travel and suspected tick-borne encephalitis, which was confirmed through specialized cerebrospinal fluid PCR. Treatment involved supportive care and antiviral therapy. The patient's parents flew in but faced language barriers; hospital staff arranged translation services. Full neurological recovery took 6 weeks.
A 45-year-old female ceramic artist presented with intermittent abdominal pain and flushing, dismissed by previous doctors as IBS. Dr. Sagcan noted the correlation with certain foods and ordered urinary 5-HIAA testing, diagnosing carcinoid syndrome from a small intestinal neuroendocrine tumor. Treatment involved somatostatin analogs and surgical resection. Her recovery allowed return to work in 3 months, with her studio collective organizing meal deliveries during treatment.
A 68-year-old retired mathematics professor with controlled hypertension developed progressive leg weakness and dark urine after starting a new herbal supplement. Dr. Sagcan diagnosed statin-induced necrotizing autoimmune myopathy through muscle biopsy and anti-HMGCR antibody testing. Treatment involved immunosuppressants and plasma exchange. The patient's daughter, a pharmacist, helped identify the supplement interaction. Rehabilitation took 9 months with partial recovery.
A 31-year-old Syrian refugee and construction worker presented with cough and night sweats, initially treated for bronchitis elsewhere. Dr. Sagcan noted his occupational silica dust exposure and ordered specialized testing, diagnosing chronic beryllium disease mimicking sarcoidosis. Treatment involved corticosteroids and removal from exposure. The patient's limited Turkish language skills and precarious immigration status complicated care coordination; Dr. Sagcan's team worked with a refugee health organization.
A 52-year-old female executive with a pacemaker for complete heart block developed recurrent syncope despite normal device checks. Dr. Sagcan identified pacemaker syndrome through hemodynamic monitoring during position changes, requiring device reprogramming and beta-blocker therapy. Her demanding job complicated medication adherence until her assistant was trained to provide reminders. Symptoms resolved completely within 2 weeks.
A 27-year-old professional freediver presented with exercise-induced dizziness and shortness of breath. Dr. Sagcan suspected patent foramen ovale after noting symptoms correlated with Valsalva maneuvers during dives. Contrast echocardiography confirmed the diagnosis, and percutaneous closure was performed. The patient's diving team collaborated on a gradual return-to-sport protocol over 4 months.
An 81-year-old grandmother with Alzheimer's disease was brought by her grandson for worsening confusion. Previous doctors attributed it to dementia progression, but Dr. Sagcan identified autoimmune encephalitis through neural antibody testing in CSF. Treatment with IVIG and rituximab led to significant cognitive improvement. The multigenerational family attended education sessions to manage expectations about her fluctuating symptoms.
A 38-year-old vegan software developer presented with numbness and balance issues. Multiple neurologists had found no cause. Dr. Sagcan identified copper deficiency myelopathy through specialized testing, caused by zinc supplementation and dietary factors. Treatment involved copper supplementation and dietary modification. Recovery was gradual over 12 months with help from a nutritionist who understood vegan nutritional challenges.
A 57-year-old fisherman from the Aegean coast presented with abdominal swelling and confusion. Previous providers suspected cirrhosis, but Dr. Sagcan identified hepatic sarcoidosis through liver biopsy and ACE level testing. Treatment with prednisone led to dramatic improvement. His fishing cooperative arranged for his boat to be maintained during his 4-month treatment period.
A 34-year-old pregnant woman in her second trimester developed hypertension and proteinuria. While preeclampsia was suspected, Dr. Sagcan diagnosed atypical hemolytic uremic syndrome through ADAMTS13 testing. Treatment with eculizumab allowed continuation of pregnancy to 36 weeks. Her husband documented the entire journey in a blog that became a resource for other rare disease patients.
A 70-year-old retired diplomat with extensive travel history presented with chronic diarrhea and weight loss. Multiple gastroenterologists found no cause. Dr. Sagcan identified tropical sprue through duodenal biopsy and response to tetracycline therapy. The patient's detailed travel diaries helped identify exposure timing. Complete recovery took 8 months with nutritional support.
A 41-year-old firefighter developed recurrent fevers and joint pain after a warehouse fire. Initially diagnosed with reactive arthritis, Dr. Sagcan identified metal fume fever progressing to polymer fume fever from specific burned materials. Treatment involved chelation therapy and pulmonary rehabilitation. His firehouse colleagues raised funds for his family during his 6-month disability period.