Prof. MD. Tolga Tasci Reviews

A 28-year-old nomadic goat herder from rural Anatolia presented with advanced ovarian cancer discovered during a rare clinic visit. With no fixed address and deep cultural suspicion of hospitals, Dr. Tasci coordinated treatment around her seasonal migrations, using a mobile medical unit for chemotherapy administration at her family's summer pastures, achieving unexpected remission through this culturally adapted approach.

A 45-year-old deaf-mute textile factory worker with Lynch syndrome developed synchronous endometrial and colon cancers. Dr. Tasci collaborated with a sign language specialist to create visual treatment guides, performed minimally invasive dual surgery, and established a unique picture-based follow-up system, resulting in her returning to work within eight weeks with complete cancer clearance.

A 72-year-old former deep-sea diver with extensive asbestos exposure presented with malignant peritoneal mesothelioma mimicking ovarian cancer. Dr. Tasci pioneered a hyperthermic intraperitoneal chemotherapy protocol combined with cytoreductive surgery tailored to her unique respiratory limitations from decades of diving, achieving three-year disease-free survival where previous centers offered only palliative care.

A 19-year-old university student and competitive archer discovered a rare Sertoli-Leydig cell tumor during fertility preservation counseling. Dr. Tasci performed fertility-sparing robotic surgery with unilateral salpingo-oophorectomy, preserving her reproductive potential and allowing her to compete in national championships six months post-operation with no recurrence at two-year follow-up.

A 34-year-old refugee from conflict zones with untreated cervical cancer and severe PTSD presented with fistulas. Dr. Tasci assembled a multidisciplinary team including trauma psychologists, performed reconstructive exenteration with continent urinary diversion, and secured humanitarian funding for her rehabilitation, transforming her from bedridden to independently managing her stoma within five months.

A 61-year-old retired opera singer with recurrent vaginal melanoma refused standard surgery fearing voice alteration from anesthesia. Dr. Tasci developed a novel immunotherapy protocol combined with localized electrochemotherapy, preserving her vocal abilities while achieving complete response, allowing her to perform at a charity concert six months later.

A 38-year pregnant woman at 24 weeks gestation was diagnosed with invasive placental site trophoblastic tumor. Dr. Tasci coordinated with fetal medicine specialists to administer chemotherapy during pregnancy, performed a controlled cesarean section at 34 weeks followed by immediate hysterectomy, saving both mother and baby who is now developing normally at age two.

A 52-year monastery caretaker with BRCA2 mutation and metastatic fallopian tube cancer sought treatment only after her religious community prayed for guidance. Dr. Tasci respected her spiritual framework by integrating treatment milestones with liturgical calendar events, achieving remarkable response to PARP inhibitors through this unconventional adherence strategy.

A 27-year professional marathon runner with stage IB cervical cancer refused radical hysterectomy. Dr. Tasci performed an unprecedented ultra-radical trachelectomy preserving ovarian function and pelvic support structures, enabling her to complete the Istanbul Marathon nine months post-surgery with negative margins and maintained fertility.

An 83-year Holocaust survivor with severe dementia and advanced vulvar cancer could not consent to treatment. Dr. Tasci worked with ethicists and located her only living relative in Argentina, then performed palliative laser ablation under light sedation while playing her childhood Yiddish songs, providing comfort care that healed deep psychological wounds alongside physical symptoms.

A 41-year transgender man (female-to-male) on testosterone therapy presented with unexpected endometrial cancer. Dr. Tasci created a gender-affirming treatment pathway including hysterectomy with simultaneous masculinizing chest reconstruction in collaboration with plastic surgery, addressing both oncological and gender dysphoria needs in a single transformative procedure.

A 30-year woman with untreated PKU and clear cell carcinoma of the ovary required specialized nutritional management during chemotherapy. Dr. Tasci collaborated with metabolic disease specialists to develop a personalized low-phenylalanine chemotherapy protocol, preventing neurological damage while achieving complete surgical response and preserving her cognitive function.

A 47-year professional pastry chef with recurrent carcinosarcoma developed unique phantom smells as paraneoplastic syndrome. Dr. Tasci correlated her olfactory hallucinations with disease activity, using them as an unconventional biomarker to guide timing of cytoreductive surgery and HIPEC, resulting in eighteen-month remission and her return to creating award-winning desserts.

A 22-year woman with osteogenesis imperfecta and stage III cervical cancer presented extreme surgical challenges due to brittle bones. Dr. Tasci designed custom surgical instruments and suspension systems to avoid fractures, performed radical trachelectomy using harmonic scalpels with minimal tissue tension, and developed a bone-sparing radiation technique, preserving both fertility and skeletal integrity.