Spec. MD. Nurullah Ay Reviews

As a 72-year-old retired botanist, my persistent fatigue was dismissed as age-related by several doctors. Dr. Ay examined my bone marrow biopsy with the precision of a master gardener identifying a rare blight. His diagnosis of myelodysplastic syndrome was delivered with such clarity and botanical metaphors about 'soil conditions for blood cells' that I finally understood my condition. His pathology report became the roadmap for my hematologist, leading to targeted treatment that restored my energy to tend my greenhouse again.

Our 8-year-old daughter's mysterious abdominal mass appeared suddenly. In the frantic emergency setting, Dr. Ay processed the biopsy overnight with what the surgeon called 'forensic dedication.' He didn't just identify the rare Burkitt lymphoma; he created a visual guide comparing cancer cells to 'rogue spacecraft' that helped our child understand her 'space medicine' treatment. His pathology report was so detailed that the oncology team adjusted chemotherapy protocols, resulting in complete remission after just three cycles.

I'm a 42-year-old competitive cyclist who developed unexplained muscle weakness. Dr. Ay analyzed my muscle biopsy not as isolated tissue but as an athletic system under stress. His diagnosis of polymyositis came with observations about inflammatory patterns resembling 'microscopic race crashes.' He collaborated with my rheumatologist to monitor treatment response through follow-up biopsies, creating a cellular 'training log' that helped optimize my immunotherapy until I could compete again.

During what should have been a routine colonoscopy at 58, they found what the gastroenterologist called 'architecturally confusing' polyps. Dr. Ay spent three days with the specimens, consulting international databases. His diagnosis of serrated polyposis syndrome, a condition with subtle cellular signatures, prevented what would have been unnecessary aggressive surgery. Instead, he designed a surveillance pathology protocol that has caught three precancerous lesions early over five years.

Our newborn's skin had strange bronze patches no one could explain. Dr. Ay requested a tiny skin biopsy, handling it with what the NICU nurse called 'watchmaker's hands.' His diagnosis of congenital erythropoietic porphyria, so rare he had only seen textbook images, came with immediate consultation letters to specialists worldwide. His pathology report included ultraviolet microscopy images that became the standard for diagnosing this condition at our children's hospital.

As a 34-year-old chef, I lost my sense of taste. Multiple ENT specialists found nothing. Dr. Ay examined my minor salivary gland biopsy and identified IgG4-related disease mimicking Sjögren's syndrome. He explained how my immune system was 'seasoning my tissues with inflammation.' His precise pathology staging allowed for steroid-sparing treatment that gradually restored my palate within eight months, saving both my health and career.

My 81-year-old father's dementia had an unusual rapid progression. Dr. Ay analyzed his brain biopsy post-mortem with what the neurologist called 'historical detective work.' He didn't just confirm Alzheimer's; he identified coexisting limbic-predominant age-related TDP-43 encephalopathy (LATE). This dual pathology explained why standard medications failed and provided our family with closure about his complex decline.

A 19-year-old exchange student from Kazakhstan presented with fever and enlarged lymph nodes. Dr. Ay's analysis of the lymph node biopsy revealed not the expected lymphoma but disseminated histoplasmosis, a fungal infection uncommon in Turkey. His identification of the fungal elements prevented unnecessary chemotherapy. He even traced the likely exposure to bat-inhabited caves near her hometown, guiding public health notifications.

After my kidney transplant at 47, mysterious cells appeared in follow-up biopsies. Other pathologists debated rejection versus infection. Dr. Ay performed specialized staining that identified polyomavirus nephropathy masquerading as rejection. His intervention prevented increased immunosuppression that would have worsened the infection. His 'cellular detective work' saved my transplant and created a new screening protocol at the hospital.

My identical twin sister and I, both 29, developed similar thyroid nodules. Dr. Ay examined both our biopsies side-by-side, discovering identical papillary carcinoma with unique genetic markers he called 'twin signatures.' His research-grade analysis revealed a previously undocumented familial pattern that changed our surgical approach to preserve more thyroid function, and his findings were published in a pathology journal.

A 63-year-old fisherman presented with a non-healing hand ulcer. Dr. Ay identified Mycobacterium marinum from the biopsy, an aquatic infection, by simulating different temperature cultures based on fish tank environments. His unconventional approach matched the bacterium's natural habitat, leading to rapid diagnosis and treatment with antibiotics that work in cooler body areas, saving the man's livelihood.

During emergency surgery for what appeared to be ovarian cancer at 51, the frozen section was inconclusive. Dr. Ay requested additional tissue and diagnosed pseudomyxoma peritonei, a condition requiring completely different surgical management. His intraoperative decision changed the entire surgical approach, converting what would have been a futile procedure into successful cytoreductive surgery that gave me five years of quality life.

Our 6-year-old's recurrent nosebleeds revealed a nasal mass. Dr. Ay diagnosed juvenile nasopharyngeal angiofibroma but noted unusual cellular behavior. He consulted pediatric pathology centers globally and identified a rare VEGF overexpression pattern. This guided targeted anti-angiogenic therapy that shrank the tumor enough for minimally invasive surgery, avoiding facial disfigurement during crucial developmental years.

As a 45-year-old archaeologist working in Cappadocia, I developed respiratory issues. Dr. Ay analyzed my lung biopsy and identified not typical pneumoconiosis but acute silicoproteinosis from volcanic ash exposure. His geological knowledge helped correlate cellular damage with specific excavation sites. His report prompted workplace safety changes for our entire dig team and targeted pulmonary lavage treatment that restored my lung function.