About Autoimmune Hemophilia
Key Highlights
-
Managed by specialized hematologists with expertise in complex bleeding disorders.Treatment aims for dual goals: immediate bleeding control and long-term antibody eradication.Utilizes targeted therapies to bypass the immune system's attack on clotting factors.Can lead to complete remission, restoring normal coagulation function.Involves a personalized treatment plan based on bleeding severity and inhibitor titer.
Who is this surgery for?
- Unexplained, spontaneous bleeding episodes (e.g., large bruises, muscle hematomas, mucosal bleeding).
- Prolonged bleeding after surgery, trauma, or childbirth without a prior bleeding history.
- Isolated prolonged activated partial thromboplastin time (aPTT) that does not correct with mixing studies.
- Suspicion of an acquired inhibitor to clotting factor VIII confirmed by laboratory tests like the Bethesda assay.
- Bleeding unresponsive to standard hemostatic measures in patients without congenital hemophilia.
How to prepare
- Comprehensive hematological consultation and review of full medical history.
- Blood tests including complete blood count (CBC), coagulation profile (PT/INR, aPTT), and specific factor assays.
- Inhibitor screening and quantification (Bethesda or Nijmegen-modified Bethesda assay).
- Imaging (e.g., ultrasound, MRI) may be needed to assess the extent of internal bleeding.
- Discussion of treatment options, including immunosuppressive risks, and obtaining informed consent.
- Planning for potential hospital admission for severe bleeding or initiation of intensive therapy.
Risks & possible complications
- Risk of severe, life-threatening bleeding (e.g., retroperitoneal, intracranial).
- Complications from immunosuppressive therapy: increased infection risk, organ toxicity, and secondary malignancies.
- Anaphylactic or thrombotic reactions to bypassing agents used for bleeding control.
- Treatment failure or relapse where the inhibitor persists or returns.
- Side effects like hypertension, hyperglycemia, or mood changes from corticosteroids.
Recovery & hospital stay
- Acute Phase: Hospital monitoring until bleeding is controlled; regular checks of hemoglobin and coagulation parameters.
- Immunosuppression Phase: Outpatient management with frequent follow-ups to monitor treatment response and side effects.
- Regular laboratory monitoring (aPTT, inhibitor titer) to assess remission status.
- Gradual tapering of immunosuppressive medications under hematologist guidance over several months.
- Avoidance of high-risk activities and medications (like NSAIDs) that can promote bleeding until remission is stable.
- Long-term follow-up is essential to detect and manage potential relapses early.
-
Typical hospital stay: 5-14 days
-
Expected recovery time: 3-6 months for immunosuppressive therapy course and stabilization
Frequently Asked Questions
If you are considering autoimmune hemophilia in Turkey, these questions and answers can help you make a confident, informed decision.
Top-rated hospitals in Turkey with hematology departments and experienced surgeons are ideal for this procedure. Use MediFyr to compare facilities, reviews, and doctor profiles before you decide.
Look at the doctor’s years of experience, hospital association, patient reviews, and how often they perform autoimmune hemophilia. MediFyr helps you compare hematologists and book consultations online.
The overall cost depends on hospital category, surgeon’s experience, room type, implant or device used (if any), length of stay, tests, and post-operative care. Our team can help you get cost estimates from multiple hospitals before you decide.
Procedure cost in other countries
Here is an overview of how the estimated cost, hospital stay, and recovery time for autoimmune hemophilia compare across other countries where we have data.
| Country | Estimated cost range | Typical stay | Recovery time | View details |
|---|---|---|---|---|
| India | USD 1,632 – USD 8,701 | 5-14 days | ~ 3-6 months for immunosuppressive therapy course and stabilization | Know More |
| Turkey | USD 12,079 – USD 64,420 | 5-14 days | ~ 3-6 months for immunosuppressive therapy course and stabilization | Know More |
As a 72-year-old retired archaeologist with...
As a 72-year-old retired archaeologist with rare Waldenström's macroglobulinemia, I'd consulted specialists across Europe with no clear treatment path. Dr. Shimoni's revolutionary approach using targeted immunotherapy not only put my cancer in remission but allowed me to continue my fieldwork in Jordan just three months later.
Hematologists for Autoimmune Hemophilia
Explore experienced hematologists who regularly perform autoimmune hemophilia and provide pre- and post-operative care in Turkey.
- 23 Years Experience
- Hematologist
Liv Hospital Ankara
- 23 Years Experience
- Hematologist
Liv Hospital Ankara
- 23 Years Experience
- Hematologist
Liv Hospital Ankara
- 23 Years Experience
- Hematologist
Liv Hospital Ankara