About Amniocentesis
Key Highlights
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Provides a definitive diagnosis for many chromosomal and genetic conditions.High accuracy rate (over 99% for detecting conditions like Down syndrome).Can detect neural tube defects by measuring alpha-fetoprotein (AFP) levels.Allows for informed family planning and preparation for potential special care needs.Performed under continuous ultrasound guidance for precision and safety.Results can offer significant reassurance when they are normal./ul
Who is this surgery for?
- Abnormal results from first or second-trimester screening tests (e.g., NIPT, quad screen).
- Advanced maternal age (typically 35 years or older at delivery).
- Previous pregnancy or child with a chromosomal abnormality or neural tube defect.
- Family history of a specific genetic disorder (e.g., cystic fibrosis, sickle cell disease).
- Ultrasound findings suggestive of a fetal abnormality.
- Parents known to be carriers of a genetic translocation or disorder.
How to prepare
- A detailed counseling session with a genetic counselor and obstetrician to discuss risks, benefits, and alternatives.
- A targeted ultrasound is performed to confirm gestational age, check the baby's anatomy, and locate the placenta.
- The patient may be asked to have a full bladder for the initial ultrasound, but it is often emptied before the needle insertion.
- No special dietary restrictions are typically required.
- Informed consent is obtained after all questions are addressed.
Risks & possible complications
- Miscarriage: The primary risk, estimated at about 0.1% to 0.3% (1 in 300 to 1 in 1000 procedures).
- Vaginal spotting or amniotic fluid leakage (usually resolves on its own).
- Mild cramping or discomfort at the needle insertion site.
- Very rare risks include uterine infection (chorioamnionitis), needle injury to the fetus, or sensitization of Rh-negative mothers (prevented with Rhogam injection).
Recovery & hospital stay
- Immediate rest for 24-48 hours is advised; avoid strenuous activity, heavy lifting, and sexual intercourse.
- Monitor for concerning signs such as fever, chills, severe abdominal pain, persistent cramping, or significant vaginal fluid leakage/bleeding.
- Most women can resume normal, light activities the next day if they feel well.
- Results from genetic tests typically take 10-14 days, while AFP results for neural tube defects are faster.
- A follow-up appointment is scheduled to discuss the results in detail.
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Typical hospital stay: 0 days (outpatient procedure)
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Expected recovery time: 1-2 days
Frequently Asked Questions
If you are considering amniocentesis in India, these questions and answers can help you make a confident, informed decision.
Popular choices for amniocentesis in India include Kamineni Hospital, King Koti, Manipal Hospital Old Airport Road, Manipal Hospital Mukundapur, SIMS Hospital Vadapalani, Manipal Hospital Dwarka, known for experienced specialists and advanced surgical infrastructure.
Look at the doctor’s years of experience, hospital association, patient reviews, and how often they perform amniocentesis. MediFyr helps you compare obstetrics and gynaecologists and book consultations online.
The overall cost depends on hospital category, surgeon’s experience, room type, implant or device used (if any), length of stay, tests, and post-operative care. Our team can help you get cost estimates from multiple hospitals before you decide.
Procedure cost in other countries
Here is an overview of how the estimated cost, hospital stay, and recovery time for amniocentesis compare across other countries where we have data.
Top hospitals for Amniocentesis in India
These partner hospitals in India have dedicated obstetrics and gynaecology teams and experience managing patients undergoing amniocentesis.
Robert Smith, a 42-year-old first-time father...
Robert Smith, a 42-year-old first-time father and high school history teacher, and his wife, Emma, 39, had struggled with infertility for five years before conceiving through IVF. At their 12-week scan, the nuchal translucency measurement was slightly increased. Their obstetrician, Dr. Evans, gently explained that Robert's advanced paternal age, combined with the scan finding, elevated their risk for chromosomal conditions like Down syndrome. She recommended amniocentesis for a definitive diagnosis, stating, 'I know this is a lot to process. This test can give you clear answers to help you prepare, whatever the path forward looks like.' The procedure itself was a tense 20 minutes; Robert held Emma's hand, both focusing on the ultrasound screen showing their active baby, trying to ignore the pinch and pressure. The recovery was physically straightforward for Emma, a day of rest with mild cramping. Emotionally, the two-week wait for results was agonizing, filled with 'what-ifs' and quiet anxiety. When the call finally came with news of normal chromosomes, their relief was profound, replaced by cautious joy and a renewed ability to bond with the pregnancy.
Obstetrics and Gynaecologists for Amniocentesis
Explore experienced obstetrics and gynaecologists who regularly perform amniocentesis and provide pre- and post-operative care in India.
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Manipal Hospital Old Airport Road, Bangalore