Learn about Amniotic Fluid Acetylcholinesterase Treatment in India — how it works, who it is for, recovery timelines, and what to expect before and after surgery. Compare hospitals and doctors experienced in Amniotic Fluid Acetylcholinesterase and request assistance for cost estimates or appointments.

About Amniotic Fluid Acetylcholinesterase

Amniotic Fluid Acetylcholinesterase (AChE) is a specialized diagnostic test performed by a Pathologist to detect neural tube defects (NTDs) in a developing fetus. This biochemical analysis measures the level of the enzyme acetylcholinesterase in a sample of amniotic fluid obtained via amniocentesis. Elevated AChE levels, particularly when combined with an elevated alpha-fetoprotein (AFP) result, are strongly indicative of an open NTD such as spina bifida or anencephaly. This test is a critical second-tier investigation following a positive AFP screening, providing higher specificity to confirm or rule out these serious congenital conditions. It aids in accurate prenatal diagnosis, enabling informed decision-making and appropriate pregnancy management.

Key Highlights

    Provides high specificity for diagnosing open neural tube defects (NTDs) like spina bifida.Serves as a crucial confirmatory test following a positive maternal serum alpha-fetoprotein (AFP) screening.Performed by expert pathologists in a controlled laboratory setting for accurate results.Helps guide critical prenatal management and family counseling decisions.Involves analysis of a small amniotic fluid sample already collected during amniocentesis.

Who is this surgery for?

  • Elevated maternal serum alpha-fetoprotein (MSAFP) or amniotic fluid AFP levels.
  • Family history or previous pregnancy with a neural tube defect.
  • Ultrasound findings suggestive of a fetal structural abnormality, particularly of the spine or skull.
  • Maternal use of certain anti-seizure medications (e.g., valproate, carbamazepine) known to increase NTD risk.
  • As part of a comprehensive prenatal diagnostic workup for high-risk pregnancies.

How to prepare

  • The primary preparation is for the amniocentesis procedure, which must be performed first to obtain the fluid sample.
  • Patient counseling regarding the purpose, benefits, and risks of both amniocentesis and the AChE test.
  • No specific dietary or medication restrictions are required for the laboratory analysis itself.
  • Ensuring the amniotic fluid sample is properly collected, labeled, and transported to the pathology laboratory.

Risks & possible complications

  • The primary risks are associated with the preceding amniocentesis procedure (e.g., minor cramping, fluid leakage, very low risk of infection or miscarriage).
  • Risk of false-positive or false-negative results, though specificity is high when combined with AFP.
  • Psychological stress and anxiety while awaiting test results.
  • The test does not detect closed neural tube defects or all types of congenital anomalies.

Recovery & hospital stay

  • Recovery is primarily from the amniocentesis procedure. Rest is advised for 24-48 hours.
  • Monitor for signs of complications from amniocentesis, such as fever, severe cramping, or fluid loss.
  • Post-procedure care involves follow-up with the obstetrician or genetic counselor to discuss the AChE test results.
  • No specific physical recovery is needed for the laboratory analysis performed by the pathologist.
  • Emotional support and counseling are important components of post-result care.
  • checked Typical hospital stay: 0 days (outpatient procedure for amniocentesis; lab test is performed on collected sample)
  • checked Expected recovery time: 1-2 days (from the amniocentesis procedure)

Frequently Asked Questions

If you are considering amniotic fluid acetylcholinesterase in India, these questions and answers can help you make a confident, informed decision.

Procedure cost in other countries

Here is an overview of how the estimated cost, hospital stay, and recovery time for amniotic fluid acetylcholinesterase compare across other countries where we have data.

Country Estimated cost range Typical stay Recovery time View details
India USD 27 – USD 65 0 days (outpatient procedure for amniocentesis; lab test is performed on collected sample) ~ 1-2 days (from the amniocentesis procedure) Know More
Turkey USD 201 – USD 483 0 days (outpatient procedure for amniocentesis; lab test is performed on collected sample) ~ 1-2 days (from the amniocentesis procedure) Know More
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Pathologist Specialists for Amniotic Fluid Acetylcholinesterase

Explore experienced pathologist specialists who regularly perform amniotic fluid acetylcholinesterase and provide pre- and post-operative care in India.

Dr. Mohan Chandra Mondal
  • 34 Years Experience
  • Pathologist Specialist
Speaks: English, Hindi
Next available on
02/Feb: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital EM Bypass

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Dr. Kirti Pandia
  • 11 Years Experience
  • Pathologist Specialist
Speaks: English, Hindi
Next available on
02/Feb: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Jaipur

OPD-desk synced • Updated
Dr. Radha Kumari Rokkam
  • 24 Years Experience
  • Pathologist Specialist
Speaks: English, Hindi
Next available on
02/Feb: 08:00 AM - 08:00 PM

Metro Hospital Noida Sector 11

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Dr. Sowmya Kommineni
  • 30 Years Experience
  • Pathologist Specialist
Speaks: English, Hindi
Next available on
02/Feb: 08:00 AM - 08:00 PM

MediFyr Plus Kamineni Hospital Vijayawada

OPD-desk synced • Updated
Dr. Sandeep Sriram
  • 34 Years Experience
  • Pathologist Specialist
Speaks: English, Hindi
Next available on
02/Feb: 08:00 AM - 08:00 PM

MediFyr Plus Kamineni Hospital King Koti

OPD-desk synced • Updated
Dr. A Ravi Shankar Reddy
  • 20 Years Experience
  • Pathologist Specialist
Speaks: English, Hindi
Next available on
02/Feb: 08:00 AM - 08:00 PM

MediFyr Plus Kamineni Hospital LB Nagar

OPD-desk synced • Updated
Dr. Sanhita Chatterjee
  • 13 Years Experience
  • Pathologist Specialist
Speaks: English, Hindi
Next available on
02/Feb: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital EM Bypass

OPD-desk synced • Updated
Dr. Marzook Mustafa Shaikh
  • 13 Years Experience
  • Pathologist Specialist
Speaks: English, Hindi
Next available on
02/Feb: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Goa

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Dr. Sukesh Kumar By
  • 11 Years Experience
  • Pathologist Specialist
Speaks: English, Hindi
Next available on
02/Feb: 08:00 AM - 08:00 PM

MediFyr Plus Kamineni Hospital King Koti

OPD-desk synced • Updated
Dr. T. Bharathi
  • 7 Years Experience
  • Pathologist Specialist
Speaks: English, Hindi
Next available on
02/Feb: 08:00 AM - 08:00 PM

MediFyr Plus Kamineni Hospital LB Nagar

OPD-desk synced • Updated
Dr. Sheetal Sadashiv Bankar
  • 4 Years Experience
  • Pathologist Specialist
Speaks: English, Hindi
Next available on
02/Feb: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Ranchi

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Dr. Divya
  • 30 Years Experience
  • Pathologist Specialist
Speaks: English, Hindi
Next available on
02/Feb: 08:00 AM - 08:00 PM

MediFyr Plus Kamineni Hospital King Koti

OPD-desk synced • Updated
Dr. Brizellda Dcunha
  • 11 Years Experience
  • Pathologist Specialist
Speaks: English, Hindi
Next available on
02/Feb: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Goa

OPD-desk synced • Updated
Dr. H R V Raj Kumar
  • 19 Years Experience
  • Pathologist Specialist
Speaks: English, Hindi
Next available on
02/Feb: 08:00 AM - 08:00 PM

MediFyr Plus Kamineni Hospital LB Nagar

OPD-desk synced • Updated
Dr. Kavya Shankaranarayana
  • 11 Years Experience
  • Pathologist Specialist
Speaks: English, Hindi
Next available on
02/Feb: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Kanakapura Road

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Dr. A Haripriya
  • 16 Years Experience
  • Pathologist Specialist
Speaks: English, Hindi
Next available on
02/Feb: 08:00 AM - 08:00 PM

MediFyr Plus Kamineni Hospital LB Nagar

OPD-desk synced • Updated
Dr. Tarachand T
  • 8 Years Experience
  • Pathologist Specialist
Speaks: English, Hindi
Next available on
02/Feb: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Kanakapura Road

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Dr. Mahammad Shafiuddin
  • 34 Years Experience
  • Pathologist Specialist
Speaks: English, Hindi
Next available on
02/Feb: 08:00 AM - 08:00 PM

MediFyr Plus Kamineni Hospital King Koti

OPD-desk synced • Updated
Dr. Neha Jain
  • 11 Years Experience
  • Pathologist Specialist
Speaks: English, Hindi
Next available on
02/Feb: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Jaipur

OPD-desk synced • Updated
Dr. Ankur Agarwal
  • 23 Years Experience
  • Pathologist Specialist
Speaks: English, Hindi
Next available on
02/Feb: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Jaipur

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