About Amniotic Fluid Acetylcholinesterase
Key Highlights
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Provides high specificity for diagnosing open neural tube defects (NTDs) like spina bifida.Serves as a crucial confirmatory test following a positive maternal serum alpha-fetoprotein (AFP) screening.Performed by expert pathologists in a controlled laboratory setting for accurate results.Helps guide critical prenatal management and family counseling decisions.Involves analysis of a small amniotic fluid sample already collected during amniocentesis.
Who is this surgery for?
- Elevated maternal serum alpha-fetoprotein (MSAFP) or amniotic fluid AFP levels.
- Family history or previous pregnancy with a neural tube defect.
- Ultrasound findings suggestive of a fetal structural abnormality, particularly of the spine or skull.
- Maternal use of certain anti-seizure medications (e.g., valproate, carbamazepine) known to increase NTD risk.
- As part of a comprehensive prenatal diagnostic workup for high-risk pregnancies.
How to prepare
- The primary preparation is for the amniocentesis procedure, which must be performed first to obtain the fluid sample.
- Patient counseling regarding the purpose, benefits, and risks of both amniocentesis and the AChE test.
- No specific dietary or medication restrictions are required for the laboratory analysis itself.
- Ensuring the amniotic fluid sample is properly collected, labeled, and transported to the pathology laboratory.
Risks & possible complications
- The primary risks are associated with the preceding amniocentesis procedure (e.g., minor cramping, fluid leakage, very low risk of infection or miscarriage).
- Risk of false-positive or false-negative results, though specificity is high when combined with AFP.
- Psychological stress and anxiety while awaiting test results.
- The test does not detect closed neural tube defects or all types of congenital anomalies.
Recovery & hospital stay
- Recovery is primarily from the amniocentesis procedure. Rest is advised for 24-48 hours.
- Monitor for signs of complications from amniocentesis, such as fever, severe cramping, or fluid loss.
- Post-procedure care involves follow-up with the obstetrician or genetic counselor to discuss the AChE test results.
- No specific physical recovery is needed for the laboratory analysis performed by the pathologist.
- Emotional support and counseling are important components of post-result care.
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Typical hospital stay: 0 days (outpatient procedure for amniocentesis; lab test is performed on collected sample)
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Expected recovery time: 1-2 days (from the amniocentesis procedure)
Frequently Asked Questions
If you are considering amniotic fluid acetylcholinesterase in India, these questions and answers can help you make a confident, informed decision.
Top-rated hospitals in India with pathology departments and experienced surgeons are ideal for this procedure. Use MediFyr to compare facilities, reviews, and doctor profiles before you decide.
Look at the doctor’s years of experience, hospital association, patient reviews, and how often they perform amniotic fluid acetylcholinesterase. MediFyr helps you compare pathologist specialists and book consultations online.
The overall cost depends on hospital category, surgeon’s experience, room type, implant or device used (if any), length of stay, tests, and post-operative care. Our team can help you get cost estimates from multiple hospitals before you decide.
Procedure cost in other countries
Here is an overview of how the estimated cost, hospital stay, and recovery time for amniotic fluid acetylcholinesterase compare across other countries where we have data.
| Country | Estimated cost range | Typical stay | Recovery time | View details |
|---|---|---|---|---|
| India | USD 27 – USD 65 | 0 days (outpatient procedure for amniocentesis; lab test is performed on collected sample) | ~ 1-2 days (from the amniocentesis procedure) | Know More |
| Turkey | USD 201 – USD 483 | 0 days (outpatient procedure for amniocentesis; lab test is performed on collected sample) | ~ 1-2 days (from the amniocentesis procedure) | Know More |
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Pathologist Specialists for Amniotic Fluid Acetylcholinesterase
Explore experienced pathologist specialists who regularly perform amniotic fluid acetylcholinesterase and provide pre- and post-operative care in India.
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