Learn about Amyloidosis Treatment in India — how it works, who it is for, recovery timelines, and what to expect before and after surgery. Compare hospitals and doctors experienced in Amyloidosis and request assistance for cost estimates or appointments.

About Amyloidosis

Amyloidosis is not a single procedure but a complex group of diseases characterized by the abnormal deposition of insoluble protein fibrils called amyloid in various organs and tissues, disrupting their normal function. An Internal Medicine specialist plays a central role in the diagnostic workup and management of this condition. The process involves a comprehensive evaluation, including detailed history, physical examination, blood and urine tests, imaging studies, and ultimately, a tissue biopsy (often from abdominal fat, bone marrow, or an affected organ) to confirm the diagnosis and identify the specific type of amyloid protein. Treatment is tailored to the type and organ involvement, focusing on reducing amyloid production, managing organ-specific complications, and providing supportive care to improve quality of life and prognosis.

Key Highlights

    Comprehensive diagnostic approach to identify the specific type of amyloidosis, which is crucial for targeted treatment.Multidisciplinary management led by an Internal Medicine specialist coordinating care with cardiologists, nephrologists, neurologists, and other experts.Focus on halting or slowing the production of amyloid proteins to prevent further organ damage.Personalized treatment plans that may include chemotherapy, immunotherapy, or novel targeted therapies depending on the amyloid type.Integrated supportive care to manage symptoms and improve the patient's overall quality of life.

Who is this surgery for?

  • Unexplained symptoms such as fatigue, weight loss, and swelling in the ankles and legs (edema).
  • Signs of specific organ involvement: protein in urine (kidneys), an enlarged tongue, heart failure symptoms (shortness of breath, palpitations), peripheral neuropathy (numbness, tingling), or gastrointestinal issues (diarrhea, feeling full quickly).
  • Abnormal lab findings like elevated serum free light chains, abnormal serum protein electrophoresis, or evidence of organ dysfunction without a clear cause.
  • Family history of amyloidosis or related conditions.
  • Presence of a chronic inflammatory condition or blood cell disorder that can predispose to amyloid formation.

How to prepare

  • Detailed review of the patient's complete medical history and a thorough physical examination.
  • Completion of initial blood tests (complete blood count, kidney and liver function tests, serum free light chains) and 24-hour urine collection to check for protein.
  • Imaging studies such as echocardiogram, MRI, or nuclear scans (e.g., DPD/PYP scan) to assess heart and other organ involvement.
  • Consultation with relevant specialists (e.g., cardiology, nephrology) based on suspected organ damage.
  • Psychological preparation and counseling regarding the diagnostic process and potential treatment pathways.
  • For a biopsy: fasting instructions and temporary cessation of certain medications like blood thinners, as advised by the physician.

Risks & possible complications

  • Risks associated with diagnostic biopsies, including bleeding, infection, bruising, or pain at the biopsy site.
  • Potential for adverse reactions to medications used in treatment, such as chemotherapy agents or immunomodulators (e.g., infections, low blood counts, allergic reactions).
  • Progression of the disease leading to irreversible organ failure (heart, kidney, liver, nerves) if diagnosis or treatment is delayed.
  • Complications from the amyloid deposits themselves, such as cardiac arrhythmias, kidney failure requiring dialysis, or severe neuropathy.
  • Side effects from supportive treatments, like diuretics for heart failure or medications for neuropathy.

Recovery & hospital stay

  • Recovery is highly variable and depends on the type of amyloidosis, organs affected, and the specific treatments administered.
  • Close monitoring of organ function and treatment response through regular blood tests, urine tests, and imaging.
  • Management of treatment side effects, which may require supportive medications and lifestyle adjustments.
  • Ongoing symptom management for chronic issues like fatigue, pain, or dietary modifications for gastrointestinal or kidney involvement.
  • Long-term follow-up with the Internal Medicine specialist and other involved specialists to adjust therapy and manage the chronic nature of the disease.
  • Possible referral to palliative care services for symptom management and support at any stage of the illness.
  • checked Typical hospital stay: Varies (0 days for outpatient biopsy to several weeks for intensive treatment)
  • checked Expected recovery time: Ongoing (Months to years for disease management)

Frequently Asked Questions

If you are considering amyloidosis in India, these questions and answers can help you make a confident, informed decision.

Procedure cost in other countries

Here is an overview of how the estimated cost, hospital stay, and recovery time for amyloidosis compare across other countries where we have data.

Country Estimated cost range Typical stay Recovery time View details
India INR 50 Thousand – 1.5 Million Varies (0 days for outpatient biopsy to several weeks for intensive treatment) ~ Ongoing (Months to years for disease management) Know More
Turkey TRY 175 Thousand – 5.25 Million Varies (0 days for outpatient biopsy to several weeks for intensive treatment) ~ Ongoing (Months to years for disease management) Know More

Top hospitals for Amyloidosis in India

These partner hospitals in India have dedicated internal medicine teams and experience managing patients undergoing amyloidosis.

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Manipal Hospital Ghaziabad

  • IconGhaziabad, India
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91+ Rating

Manipal Hospital Malleshwaram

  • IconBangalore, India
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5734+ Rating

Manipal Hospital Siliguri

  • IconSiliguri, India
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89+ Rating

Manipal Hospital EM Bypass

  • IconKolkata, India
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65+ Rating

Manipal Hospital Salt Lake

  • IconKolkata, India
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12320+ Rating

Manipal Hospital Kanakapura Road

  • IconBangalore, India
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185+ Rating

Manipal Hospital Ranchi

  • IconRanchi, India
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1161+ Rating

Artemis Hospital Gurgaon

  • IconGurgaon, India
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181+ Rating

KMC Hospital Mangalore

  • IconMangalore, India
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PATIENT REVIEW

Krishna Brown, a 62-year-old retired school...

Krishna Brown, a 62-year-old retired school librarian, had been feeling increasingly unwell for over a year. A gentle woman with a love for gardening, she first noticed swelling in her ankles and a profound, unshakeable fatigue that made her beloved walks with her book club friends impossible. Her hands began to feel numb and clumsy, dropping teacups. Her primary care doctor, concerned by her persistent proteinuria and an echocardiogram showing thickened heart walls, referred her to a specialist in Internal Medicine. The specialist, Dr. Evans, gently explained that Krishna's constellation of symptoms, heart issues, neuropathy, and kidney problems, pointed to a systemic disease called amyloidosis, where abnormal proteins build up in organs. A fat pad biopsy was recommended as a minimally invasive first step to confirm the diagnosis. Krishna was terrified, fearing cancer. The biopsy itself, a numbed needle aspiration from her abdomen, was quick. The emotional wait for results was agonizing. When the results confirmed AL amyloidosis, it was devastating, but also provided a clear path. She began chemotherapy targeting the plasma cells producing the abnormal protein. While treatment was tough, knowing the enemy gave her strength. A year later, her heart function has stabilized, the numbness has slightly improved, and the swelling is down. The emotional journey was from fear of the unknown to the grim acceptance of a chronic illness, but ultimately to a determined resilience. She now leads a support group for others with rare diseases, finding purpose in her journey.

Internal Medicine Specialists for Amyloidosis

Explore experienced internal medicine specialists who regularly perform amyloidosis and provide pre- and post-operative care in India.

Dr. Geetha K Subramaniyam K
  • 41 Years Experience
  • Internal Medicine Specialist
Speaks: English, Hindi
Consult Charge ₹ 600
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Yeshwanthpur, Bangalore

OPD-desk synced • Updated
Dr. Sangeshwaran
  • 11 Years Experience
  • Internal Medicine Specialist
Speaks: English, Hindi
Consult Charge ₹ 500
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Salem, Salem

OPD-desk synced • Updated
Dr. Archana D
  • 8 Years Experience
  • Internal Medicine Specialist
Speaks: English, Hindi
Consult Charge ₹ 450
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Salem, Salem

OPD-desk synced • Updated
Dr. Arun Karthik P
  • 8 Years Experience
  • Internal Medicine Specialist
Speaks: English, Hindi
Consult Charge ₹ 450
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Salem, Salem

OPD-desk synced • Updated
Dr. C Harish
  • 8 Years Experience
  • Internal Medicine Specialist
Speaks: English, Hindi
Consult Charge ₹ 500
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Salem, Salem

OPD-desk synced • Updated
Dr. Veerendra B Sutar
  • 22 Years Experience
  • Internal Medicine Specialist
Speaks: English, Hindi
Consult Charge ₹ 450
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Whitefield, Bangalore

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Dr. Ravi Kumar
  • 16 Years Experience
  • Internal Medicine Specialist
Speaks: English, Hindi
Consult Charge ₹ 450
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Whitefield, Bangalore

OPD-desk synced • Updated
Dr. Reshu Agrawal
  • 15 Years Experience
  • Internal Medicine Specialist
Speaks: English, Hindi
Consult Charge ₹ 500
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Whitefield, Bangalore

OPD-desk synced • Updated
Dr. Sanjiv Rao
  • 32 Years Experience
  • Internal Medicine Specialist
Speaks: English, Hindi
Consult Charge ₹ 850
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Old Airport Road, Bangalore

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Dr. Prashant Bhatt
  • 18 Years Experience
  • Internal Medicine Specialist
Speaks: English, Hindi
Consult Charge ₹ 900
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Patiala, Patiala

OPD-desk synced • Updated
Dr. Gurpreet Singh Dang
  • 14 Years Experience
  • Internal Medicine Specialist
Speaks: English, Hindi
Consult Charge ₹ 900
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Patiala, Patiala

OPD-desk synced • Updated
Dr. Inderjeet Kaur
  • 8 Years Experience
  • Internal Medicine Specialist
Speaks: English, Hindi
Consult Charge ₹ 450
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Patiala, Patiala

OPD-desk synced • Updated
Dr. K Sriram
  • 13 Years Experience
  • Internal Medicine Specialist
Speaks: English, Hindi
Consult Charge ₹ 900
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Vijayawada, vijayawada

OPD-desk synced • Updated
Dr. HARIKA UPPALAPATI
  • 9 Years Experience
  • Internal Medicine Specialist
Speaks: English, Hindi
Consult Charge ₹ 850
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Vijayawada, vijayawada

OPD-desk synced • Updated
Dr. Sharada Shekar
  • 43 Years Experience
  • Internal Medicine Specialist
Speaks: English, Hindi
Consult Charge ₹ 850
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Malleshwaram, Bangalore

OPD-desk synced • Updated
Dr. Dinesh Kamath
  • 36 Years Experience
  • Internal Medicine Specialist
Speaks: English, Hindi
Consult Charge ₹ 850
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Malleshwaram, Bangalore

OPD-desk synced • Updated
Dr. Basavaraj Kuntoji
  • 23 Years Experience
  • Internal Medicine Specialist
Speaks: English, Hindi
Consult Charge ₹ 650
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Malleshwaram, Bangalore

OPD-desk synced • Updated
Dr. Arun Suradkar
  • 23 Years Experience
  • Internal Medicine Specialist
Speaks: English, Hindi
Consult Charge ₹ 650
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Kharadi, Pune

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Dr. Vichar Shyam Nigam
  • 21 Years Experience
  • Internal Medicine Specialist
Speaks: English, Hindi
Consult Charge ₹ 550
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Kharadi, Pune

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Dr. Vijay Narasappa Talkad
  • 15 Years Experience
  • Internal Medicine Specialist
Speaks: English, Hindi
Consult Charge ₹ 650
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Jayanagar, Bangalore

OPD-desk synced • Updated