About Aplastic Anemia
Key Highlights
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Comprehensive management by specialists skilled in hematologic disorders.Multimodal approach combining supportive care with definitive treatments.Aims to restore bone marrow function and improve blood cell counts.Personalized treatment plans based on disease severity, patient age, and overall health.Focus on improving quality of life and long-term survival.
Who is this surgery for?
- Diagnosis of pancytopenia (low red blood cells, white blood cells, and platelets) on complete blood count (CBC).
- Presence of symptoms like severe fatigue, frequent infections, or unexplained bruising/bleeding.
- Confirmation of hypocellular bone marrow without abnormal cells via bone marrow biopsy.
- Exclusion of other causes of bone marrow failure.
- Need to determine the specific type (inherited vs. acquired) and severity of aplastic anemia.
How to prepare
- Detailed medical history and physical examination to identify potential causes or exposures.
- Complete blood count (CBC), reticulocyte count, and peripheral blood smear.
- Bone marrow aspiration and biopsy for definitive diagnosis.
- Additional tests to rule out other conditions: vitamin B12/folate levels, liver function tests, viral studies (e.g., hepatitis, parvovirus), and possibly genetic testing.
- Consultation with a hematologist for treatment planning.
- For planned therapies like ATG or transplant, pre-treatment evaluations for heart, lung, and kidney function.
Risks & possible complications
- Disease-related: Life-threatening infections, severe bleeding, and complications of severe anemia like heart failure.
- Treatment-related: Reactions to blood transfusions (fever, allergic reactions, iron overload).
- Immunosuppressive therapy risks: Increased infection risk, serum sickness, and potential for secondary cancers.
- Stem cell transplant risks: Graft-versus-host disease, graft failure, and complications from high-dose chemotherapy/radiation.
- Long-term risk of the disease evolving into myelodysplastic syndrome or acute leukemia.
Recovery & hospital stay
- Recovery is highly variable and depends on the treatment response. Supportive care is ongoing.
- After immunosuppressive therapy, it may take 3-6 months to see a significant improvement in blood counts.
- Strict infection prevention measures are crucial, including hand hygiene and avoiding sick contacts.
- Regular follow-up with blood tests to monitor counts and treatment response.
- Management of treatment side effects and long-term complications like iron overload from transfusions.
- Psychological support and nutritional counseling are important components of care.
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Typical hospital stay: Varies widely (from outpatient to several weeks)
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Expected recovery time: Several months to years
Frequently Asked Questions
If you are considering aplastic anemia in India, these questions and answers can help you make a confident, informed decision.
Popular choices for aplastic anemia in India include Manipal Hospital Ghaziabad, Manipal Hospital Malleshwaram, Manipal Hospital EM Bypass, Manipal Hospital Kanakapura Road, KMC Hospital Mangalore, known for experienced specialists and advanced surgical infrastructure.
Look at the doctor’s years of experience, hospital association, patient reviews, and how often they perform aplastic anemia. MediFyr helps you compare internal medicine specialists and book consultations online.
The overall cost depends on hospital category, surgeon’s experience, room type, implant or device used (if any), length of stay, tests, and post-operative care. Our team can help you get cost estimates from multiple hospitals before you decide.
Procedure cost in other countries
Here is an overview of how the estimated cost, hospital stay, and recovery time for aplastic anemia compare across other countries where we have data.
| Country | Estimated cost range | Typical stay | Recovery time | View details |
|---|---|---|---|---|
| India | INR 200 Thousand – 2.5 Million | Varies widely (from outpatient to several weeks) | ~ Several months to years | Know More |
| Turkey | TRY 700 Thousand – 8.75 Million | Varies widely (from outpatient to several weeks) | ~ Several months to years | Know More |
Top hospitals for Aplastic Anemia in India
These partner hospitals in India have dedicated internal medicine teams and experience managing patients undergoing aplastic anemia.
Aarav Brown, a 28-year-old software engineer...
Aarav Brown, a 28-year-old software engineer and avid hiker, began noticing unusual fatigue and frequent nosebleeds. Over several weeks, he developed persistent bruises on his arms and legs without any injury. A routine blood test revealed critically low counts of all his blood cells. His primary care physician referred him to a hematologist, who diagnosed him with severe Aplastic Anemia, likely triggered by an unknown environmental exposure. The doctor recommended immunosuppressive therapy (IST) with horse anti-thymocyte globulin (ATG) and cyclosporine as the first-line treatment, explaining it was less invasive than an immediate bone marrow transplant. Aarav underwent the five-day ATG infusion in the hospital, experiencing fever and chills as side effects. His recovery was slow; he required regular blood transfusions for months and took cyclosporine to suppress his immune system. After six months, his blood counts began to steadily improve. Emotionally, Aarav felt terrified and robbed of his active life at first. The support of his family and a patient support group helped him cope. Seeing his blood counts normalize brought immense relief and a cautious optimism, though he remains vigilant about his health.
Internal Medicine Specialists for Aplastic Anemia
Explore experienced internal medicine specialists who regularly perform aplastic anemia and provide pre- and post-operative care in India.
- 41 Years Experience
- Internal Medicine Specialist
Manipal Hospital Yeshwanthpur, Bangalore
- 11 Years Experience
- Internal Medicine Specialist
- 8 Years Experience
- Internal Medicine Specialist
- 8 Years Experience
- Internal Medicine Specialist
- 8 Years Experience
- Internal Medicine Specialist
- 22 Years Experience
- Internal Medicine Specialist
Manipal Hospital Whitefield, Bangalore
- 16 Years Experience
- Internal Medicine Specialist
Manipal Hospital Whitefield, Bangalore
- 15 Years Experience
- Internal Medicine Specialist
Manipal Hospital Whitefield, Bangalore
- 32 Years Experience
- Internal Medicine Specialist
Manipal Hospital Old Airport Road, Bangalore
- 18 Years Experience
- Internal Medicine Specialist
Manipal Hospital Patiala, Patiala
- 14 Years Experience
- Internal Medicine Specialist
Manipal Hospital Patiala, Patiala
- 8 Years Experience
- Internal Medicine Specialist
Manipal Hospital Patiala, Patiala
- 13 Years Experience
- Internal Medicine Specialist
Manipal Hospital Vijayawada, vijayawada
- 9 Years Experience
- Internal Medicine Specialist
Manipal Hospital Vijayawada, vijayawada
- 43 Years Experience
- Internal Medicine Specialist
Manipal Hospital Malleshwaram, Bangalore
- 36 Years Experience
- Internal Medicine Specialist
Manipal Hospital Malleshwaram, Bangalore
- 23 Years Experience
- Internal Medicine Specialist
Manipal Hospital Malleshwaram, Bangalore
- 23 Years Experience
- Internal Medicine Specialist
Manipal Hospital Kharadi, Pune
- 21 Years Experience
- Internal Medicine Specialist
Manipal Hospital Kharadi, Pune
- 15 Years Experience
- Internal Medicine Specialist
Manipal Hospital Jayanagar, Bangalore