About Assisted Hatching
Key Highlights
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Can improve embryo implantation rates, especially in select patient groups.Minimally invasive laboratory procedure performed on the embryo prior to transfer.May be beneficial for patients with a history of repeated IVF implantation failures.Helps embryos with a thickened outer shell (zona pellucida) to 'hatch' and implant.Often recommended for women of advanced maternal age (typically over 38).Uses precise techniques like laser, chemical, or mechanical methods to assist the embryo./ul
Who is this surgery for?
- Advanced maternal age (typically 38 years and older).
- Elevated Follicle Stimulating Hormone (FSH) levels on day 3.
- History of two or more failed IVF cycles with good-quality embryos.
- Embryos with a visibly thickened or abnormal zona pellucida.
- Poor embryo quality or slow embryo development in previous cycles.
- Frozen-thawed embryo transfer cycles, as the freezing process can harden the zona.
How to prepare
- Completion of the standard IVF process, including ovarian stimulation and egg retrieval.
- Fertilization of eggs with sperm in the lab to create embryos.
- Monitoring of embryo development for 3-5 days in the incubator.
- Selection of the best-quality embryo(s) for the procedure.
- No specific physical preparation is required from the patient for the hatching procedure itself.
- Discussion and informed consent with the fertility specialist regarding the benefits and risks.
Risks & possible complications
- Potential damage to the embryo during the hatching process, though rare with modern techniques.
- Slight increase in the risk of monozygotic (identical) twinning.
- Theoretical risk of increased susceptibility to infections, though the embryo remains in a sterile lab environment.
- No guarantee of successful implantation or pregnancy.
- The procedure does not correct underlying genetic or chromosomal abnormalities in the embryo.
Recovery & hospital stay
- There is no physical recovery needed from the assisted hatching procedure itself, as it is performed on the embryo in the lab.
- The patient proceeds with the planned embryo transfer shortly after the procedure.
- Post-transfer, standard IVF recovery and care protocols apply, including rest and avoiding strenuous activity.
- Patients will begin a prescribed course of progesterone support to prepare the uterine lining.
- A pregnancy blood test (beta hCG) is typically scheduled 10-14 days after the embryo transfer.
- Follow-up appointments with the fertility specialist are scheduled to monitor progress.
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Typical hospital stay: 0 days (outpatient lab procedure)
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Expected recovery time: 0 days (from the hatching procedure itself)
Frequently Asked Questions
If you are considering assisted hatching in India, these questions and answers can help you make a confident, informed decision.
Top-rated hospitals in India with ivf and reproductive medicine departments and experienced surgeons are ideal for this procedure. Use MediFyr to compare facilities, reviews, and doctor profiles before you decide.
Look at the doctor’s years of experience, hospital association, patient reviews, and how often they perform assisted hatching. MediFyr helps you compare ivf and reproductive medicines and book consultations online.
The overall cost depends on hospital category, surgeon’s experience, room type, implant or device used (if any), length of stay, tests, and post-operative care. Our team can help you get cost estimates from multiple hospitals before you decide.
Procedure cost in other countries
Here is an overview of how the estimated cost, hospital stay, and recovery time for assisted hatching compare across other countries where we have data.
| Country | Estimated cost range | Typical stay | Recovery time | View details |
|---|---|---|---|---|
| India | INR 15 Thousand – 40 Thousand | 0 days (outpatient lab procedure) | ~ 0 days (from the hatching procedure itself) | Know More |
| Turkey | TRY 52.5 Thousand – 140 Thousand | 0 days (outpatient lab procedure) | ~ 0 days (from the hatching procedure itself) | Know More |
Ayaan Garcia, 39, is a high...
Ayaan Garcia, 39, is a high school teacher who has been trying to conceive with her husband for four years. They have undergone three previous IVF cycles, all of which resulted in high-quality embryos that failed to implant. Each negative pregnancy test felt like a profound personal failure, chipping away at Ayaan's hope. Her fertility specialist, Dr. Evans, reviewed their history and noted that Ayaan's embryos had a slightly thickened zona pellucida, the outer shell. She recommended Assisted Hatching (AH) for their next cycle, explaining that creating a small opening in this shell could help the embryo 'hatch' and implant in the uterine lining. The procedure itself was performed in the embryology lab just before their Day 5 blastocyst transfer and was seamlessly integrated into their IVF process. Two weeks later, Ayaan received her first-ever positive beta hCG test. The emotional shift was seismic, the constant anxiety of 'what if it fails again' began to melt into cautious optimism. While early days, this successful implantation marked a pivotal turn from repeated loss to tangible hope.
IVF and Reproductive Medicines for Assisted Hatching
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