About Autoimmune Hemolytic Anemia
Key Highlights
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Offers a potential cure for severe, treatment-resistant Autoimmune Hemolytic Anemia.Aims to completely reset the malfunctioning immune system responsible for red blood cell destruction.Can eliminate or drastically reduce the need for long-term immunosuppressive medications.May improve long-term survival and quality of life in carefully selected patients.Utilizes advanced medical technology and a multidisciplinary team approach.
Who is this surgery for?
- Severe, life-threatening AIHA that does not respond to first-line treatments (corticosteroids, IVIG).
- AIHA that is refractory to second-line therapies like rituximab or other immunosuppressants.
- Patients who experience severe side effects from long-term immunosuppressive therapy.
- AIHA associated with an underlying hematologic malignancy (like lymphoma) where transplant addresses both conditions.
- Selected cases of recurrent or chronic AIHA causing significant morbidity and impacting quality of life.
How to prepare
- Comprehensive evaluation including blood tests, imaging (CT/PET scans), and heart/lung function tests.
- Identification and compatibility testing (HLA typing) of a suitable donor (sibling, unrelated donor, or cord blood).
- Dental check-up and clearance to prevent infection sources.
- Fertility preservation counseling and procedures, if desired.
- Administration of conditioning therapy (chemotherapy +/- radiation) to destroy the existing bone marrow and suppress the immune system.
- Central venous catheter placement for medication administration and blood draws.
- Psychological counseling and detailed informed consent process.
Risks & possible complications
- Graft-versus-host disease (GVHD), where donor immune cells attack the patient's body.
- Graft failure, where the new bone marrow does not engraft or function.
- Severe infections due to prolonged immune suppression before engraftment.
- Organ toxicity (e.g., liver, lungs, heart) from conditioning chemotherapy/radiation.
- Bleeding and anemia until the new marrow produces blood cells.
- Long-term risks include secondary cancers, cataracts, and infertility.
Recovery & hospital stay
- Initial hospital stay of 4-6 weeks in a sterile environment to prevent infection until engraftment occurs.
- Close monitoring of blood counts, signs of infection, and GVHD.
- Multiple blood and platelet transfusions may be required initially.
- Immunosuppressive medications (like cyclosporine) to prevent GVHD, tapered slowly over months.
- After discharge, frequent outpatient visits for monitoring and management of complications.
- Recovery of immune function is gradual; patients must avoid crowds and practice strict hygiene for several months to a year.
- Long-term follow-up is essential to monitor for late effects and disease recurrence.
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Typical hospital stay: 4-6 weeks
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Expected recovery time: 6-12 months for full immune recovery and return to normal activities
Frequently Asked Questions
If you are considering autoimmune hemolytic anemia in India, these questions and answers can help you make a confident, informed decision.
Popular choices for autoimmune hemolytic anemia in India include Miot Hospital Chennai, known for experienced specialists and advanced surgical infrastructure.
Look at the doctor’s years of experience, hospital association, patient reviews, and how often they perform autoimmune hemolytic anemia. MediFyr helps you compare bone marrow transplant specialists and book consultations online.
The overall cost depends on hospital category, surgeon’s experience, room type, implant or device used (if any), length of stay, tests, and post-operative care. Our team can help you get cost estimates from multiple hospitals before you decide.
Procedure cost in other countries
Here is an overview of how the estimated cost, hospital stay, and recovery time for autoimmune hemolytic anemia compare across other countries where we have data.
| Country | Estimated cost range | Typical stay | Recovery time | View details |
|---|---|---|---|---|
| India | INR 1.5 Million – 3.5 Million | 4-6 weeks | ~ 6-12 months for full immune recovery and return to normal activities | Know More |
| Turkey | TRY 5.25 Million – 12.3 Million | 4-6 weeks | ~ 6-12 months for full immune recovery and return to normal activities | Know More |
Top hospitals for Autoimmune Hemolytic Anemia in India
These partner hospitals in India have dedicated bone marrow transplantation teams and experience managing patients undergoing autoimmune hemolytic anemia.
Ishaan Brown, a 28-year-old software engineer,...
Ishaan Brown, a 28-year-old software engineer, was an avid rock climber until his health began to fail. For months, he battled debilitating fatigue, shortness of breath during simple walks, and a persistent yellow tinge to his eyes. Diagnosed with severe, refractory Autoimmune Hemolytic Anemia (AIHA), his immune system relentlessly attacked his own red blood cells. Steroids and immunosuppressants provided only brief respites, each relapse leaving him weaker. His hematologist, Dr. Chen, recommended an allogeneic bone marrow transplant as the only curative option, explaining it would 'reboot' his immune system. The treatment was grueling; high-dose chemotherapy wiped out his bone marrow, followed by the transplant from his matched sister. Ishaan spent weeks in isolation, battling infections and the profound fear that it wouldn't work. His emotional journey was a rollercoaster of hope and despair. Today, two years post-transplant, Ishaan is in remission. His energy has slowly returned, and while he's not back to climbing cliffs, he hikes regularly. The experience gave him a deep appreciation for life's fragility and a quiet, resilient strength. He volunteers to support other transplant patients, saying, 'They gave me a new immune system, and with it, a new perspective.'
Bone Marrow Transplant Specialists for Autoimmune Hemolytic Anemia
Explore experienced bone marrow transplant specialists who regularly perform autoimmune hemolytic anemia and provide pre- and post-operative care in India.
- 11 Years Experience
- Bone Marrow Transplant Specialist
Miot Hospital Chennai, Chennai
- 13 Years Experience
- Bone Marrow Transplant Specialist
Miot Hospital Chennai, Chennai
- 10 Years Experience
- Bone Marrow Transplant Specialist
Manipal Hospital Yeshwanthpur, Bangalore
- 24 Years Experience
- Bone Marrow Transplant Specialist
Manipal Hospital Old Airport Road, Bangalore
- 35 Years Experience
- Bone Marrow Transplant Specialist
Artemis Hospital Gurgaon, Gurgaon
- 20 Years Experience
- Bone Marrow Transplant Specialist
Artemis Hospital Gurgaon, Gurgaon
- 12 Years Experience
- Bone Marrow Transplant Specialist
Manipal Hospital Jaipur, Jaipur
- 31 Years Experience
- Bone Marrow Transplant Specialist
- 16 Years Experience
- Bone Marrow Transplant Specialist
Metro Hospital, Sector 11, Noida
- 16 Years Experience
- Bone Marrow Transplant Specialist
Metro Hospital, Sector 11, Noida
- 13 Years Experience
- Bone Marrow Transplant Specialist
Metro Hospital, Sector 11, Noida
- 7 Years Experience
- Bone Marrow Transplant Specialist
Manipal Hospital Dwarka, Delhi
- 10 Years Experience
- Bone Marrow Transplant Specialist
- 15 Years Experience
- Bone Marrow Transplant Specialist
Manipal Hospital Mukundapur, Kolkata
- 13 Years Experience
- Bone Marrow Transplant Specialist
Manipal Hospital Kanakapura Road, Bangalore
- 15 Years Experience
- Bone Marrow Transplant Specialist
Manipal Hospitals Broadway, Kolkata
- 11 Years Experience
- Bone Marrow Transplant Specialist
Artemis Hospital Gurgaon, Gurgaon
- 10 Years Experience
- Bone Marrow Transplant Specialist
Artemis Hospital Gurgaon, Gurgaon
- 17 Years Experience
- Bone Marrow Transplant Specialist
Artemis Hospital Gurgaon, Gurgaon