About Autologous Stem Cell Transplant
Key Highlights
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Utilizes the patient's own cells, eliminating the risk of graft-versus-host disease (GVHD).Allows for the administration of higher, more effective doses of chemotherapy or radiation.Can lead to long-term remission or cure for certain cancers and blood disorders.No need to find a matched donor, simplifying the logistics of the transplant process.Helps restore the body's ability to produce healthy blood cells after intensive treatment.
Who is this surgery for?
- Relapsed or refractory Hodgkin's and Non-Hodgkin's Lymphoma.
- Multiple Myeloma as a standard part of treatment.
- Certain types of Leukemia, such as Acute Myeloid Leukemia (AML) in remission.
- Germ cell tumors (testicular cancer) that have not responded to initial chemotherapy.
- Some autoimmune diseases like severe systemic sclerosis or multiple sclerosis, in specific cases.
- Amyloidosis, a disorder caused by abnormal protein buildup.
How to prepare
- Comprehensive medical evaluation including heart, lung, and kidney function tests.
- Stem cell mobilization: receiving injections (growth factors) to move stem cells from bone marrow into the bloodstream.
- Stem cell collection (apheresis): a process where blood is drawn, stem cells are separated, and the remaining blood is returned.
- Dental check-up to prevent infections from oral bacteria.
- Fertility preservation counseling, as treatment can affect fertility.
- Insertion of a central venous catheter (like a PICC line) for easy administration of drugs and stem cells.
Risks & possible complications
- Infections due to severely low white blood cell counts (neutropenia).
- Bleeding and bruising from low platelet counts (thrombocytopenia).
- Side effects from high-dose chemotherapy, such as nausea, mouth sores (mucositis), and fatigue.
- Organ damage, particularly to the heart, lungs, liver, or kidneys.
- Early or late effects on fertility.
- Risk of the original disease returning (relapse).
- In rare cases, the transplanted stem cells may fail to engraft (start growing).
Recovery & hospital stay
- Initial hospital stay in a protected environment to prevent infection while blood counts are low.
- Close monitoring of blood counts, vital signs, and for signs of infection or bleeding.
- Medications to prevent infections, manage nausea, and support cell growth.
- Nutritional support, possibly including IV nutrition, until mouth sores heal and eating is comfortable.
- Gradual increase in activity; fatigue is common and can last for months.
- Regular follow-up appointments to monitor recovery, manage side effects, and check for disease status.
- Full immune system recovery can take 6 to 12 months or longer.
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Typical hospital stay: 3-4 weeks
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Expected recovery time: 3-6 months for initial recovery; up to 1 year for full immune recovery
Frequently Asked Questions
If you are considering autologous stem cell transplant in India, these questions and answers can help you make a confident, informed decision.
Popular choices for autologous stem cell transplant in India include Miot Hospital Chennai, known for experienced specialists and advanced surgical infrastructure.
Look at the doctor’s years of experience, hospital association, patient reviews, and how often they perform autologous stem cell transplant. MediFyr helps you compare bone marrow transplant specialists and book consultations online.
The overall cost depends on hospital category, surgeon’s experience, room type, implant or device used (if any), length of stay, tests, and post-operative care. Our team can help you get cost estimates from multiple hospitals before you decide.
Procedure cost in other countries
Here is an overview of how the estimated cost, hospital stay, and recovery time for autologous stem cell transplant compare across other countries where we have data.
| Country | Estimated cost range | Typical stay | Recovery time | View details |
|---|---|---|---|---|
| India | INR 1.5 Million – 3.5 Million | 3-4 weeks | ~ 3-6 months for initial recovery; up to 1 year for full immune recovery | Know More |
| Turkey | TRY 5.25 Million – 12.3 Million | 3-4 weeks | ~ 3-6 months for initial recovery; up to 1 year for full immune recovery | Know More |
Top hospitals for Autologous Stem Cell Transplant in India
These partner hospitals in India have dedicated bone marrow transplantation teams and experience managing patients undergoing autologous stem cell transplant.
Krishna Verma, a 58-year-old former school...
Krishna Verma, a 58-year-old former school principal from Delhi, was diagnosed with Multiple Myeloma. A pillar of his community, he had been experiencing persistent back pain, debilitating fatigue, and unexplained weight loss for months. Blood tests and a bone marrow biopsy confirmed the cancer. His oncologist, Dr. Mehta, explained that while initial chemotherapy had put him in remission, an Autologous Stem Cell Transplant was the best chance for a long-term cure, using his own stem cells to 'reset' his immune system after high-dose chemo. The treatment was grueling; the high-dose chemotherapy left him extremely weak and nauseous. The transplant day itself felt anticlimactic, just a bag of his own cells being infused. The hardest part was the two weeks in protective isolation as his blood counts recovered, feeling lonely and vulnerable. After discharge, recovery was slow but steady. At his six-month check-up, he was in deep remission. Emotionally, Krishna moved from a place of fear and uncertainty, worrying about being a burden to his family, to one of profound gratitude and a renewed purpose. He now volunteers to counsel other patients, calling his transplant a 'second birth'.
Bone Marrow Transplant Specialists for Autologous Stem Cell Transplant
Explore experienced bone marrow transplant specialists who regularly perform autologous stem cell transplant and provide pre- and post-operative care in India.
- 11 Years Experience
- Bone Marrow Transplant Specialist
Miot Hospital Chennai, Chennai
- 13 Years Experience
- Bone Marrow Transplant Specialist
Miot Hospital Chennai, Chennai
- 10 Years Experience
- Bone Marrow Transplant Specialist
Manipal Hospital Yeshwanthpur, Bangalore
- 24 Years Experience
- Bone Marrow Transplant Specialist
Manipal Hospital Old Airport Road, Bangalore
- 35 Years Experience
- Bone Marrow Transplant Specialist
Artemis Hospital Gurgaon, Gurgaon
- 20 Years Experience
- Bone Marrow Transplant Specialist
Artemis Hospital Gurgaon, Gurgaon
- 12 Years Experience
- Bone Marrow Transplant Specialist
Manipal Hospital Jaipur, Jaipur
- 31 Years Experience
- Bone Marrow Transplant Specialist
- 16 Years Experience
- Bone Marrow Transplant Specialist
Metro Hospital, Sector 11, Noida
- 16 Years Experience
- Bone Marrow Transplant Specialist
Metro Hospital, Sector 11, Noida
- 13 Years Experience
- Bone Marrow Transplant Specialist
Metro Hospital, Sector 11, Noida
- 7 Years Experience
- Bone Marrow Transplant Specialist
Manipal Hospital Dwarka, Delhi
- 10 Years Experience
- Bone Marrow Transplant Specialist
- 15 Years Experience
- Bone Marrow Transplant Specialist
Manipal Hospital Mukundapur, Kolkata
- 13 Years Experience
- Bone Marrow Transplant Specialist
Manipal Hospital Kanakapura Road, Bangalore
- 15 Years Experience
- Bone Marrow Transplant Specialist
Manipal Hospitals Broadway, Kolkata
- 11 Years Experience
- Bone Marrow Transplant Specialist
Artemis Hospital Gurgaon, Gurgaon
- 10 Years Experience
- Bone Marrow Transplant Specialist
Artemis Hospital Gurgaon, Gurgaon
- 17 Years Experience
- Bone Marrow Transplant Specialist
Artemis Hospital Gurgaon, Gurgaon