Learn about Central Nervous System Lymphoma Treatment in India — how it works, who it is for, recovery timelines, and what to expect before and after surgery. Compare hospitals and doctors experienced in Central Nervous System Lymphoma and request assistance for cost estimates or appointments.

About Central Nervous System Lymphoma

Central Nervous System (CNS) Lymphoma treatment is a specialized oncological procedure targeting a rare form of non-Hodgkin lymphoma that originates in or spreads to the brain, spinal cord, or cerebrospinal fluid. Led by a neuro-oncologist or medical oncologist, the primary treatment is typically high-dose methotrexate-based chemotherapy, often combined with whole-brain radiation therapy or newer targeted agents like rituximab. The goal is to achieve remission by eradicating cancerous lymphocytes while preserving neurological function. Treatment planning is highly individualized, considering factors like the patient's age, overall health, and the lymphoma's specific characteristics. Due to the blood-brain barrier, specialized drug regimens and delivery methods are crucial for effective treatment.

Key Highlights

    Targeted treatment specifically designed to cross the protective blood-brain barrier.Multidisciplinary approach involving neuro-oncologists, radiation oncologists, and neurologists for comprehensive care.Utilizes high-dose chemotherapy protocols, such as methotrexate, which are effective against CNS lymphoma cells.Can incorporate advanced techniques like autologous stem cell transplant for eligible patients to allow for more aggressive therapy.Aims to achieve complete remission and improve survival rates while managing neurological symptoms.

Who is this surgery for?

  • Diagnosis of primary CNS lymphoma (PCNSL), a lymphoma confined to the brain, eyes, or spinal cord.
  • Secondary CNS lymphoma, where systemic lymphoma has spread to the central nervous system.
  • Presence of neurological symptoms such as confusion, personality changes, seizures, weakness, or vision problems linked to lymphoma.
  • Confirmation of lymphoma cells in the cerebrospinal fluid (CSF) via lumbar puncture.
  • Radiographic evidence (MRI) of brain or spinal cord lesions suggestive of lymphoma, typically confirmed by biopsy.

How to prepare

  • Comprehensive neurological examination and review of medical history by the oncologist.
  • Diagnostic imaging, primarily MRI of the brain and/or spine with contrast.
  • Stereotactic brain biopsy to obtain a definitive tissue diagnosis and guide treatment.
  • Lumbar puncture to analyze cerebrospinal fluid for lymphoma cells.
  • Baseline tests including complete blood count, kidney function tests (crucial for methotrexate), liver function tests, and HIV testing.
  • Consultation with the treatment team to discuss the treatment plan, goals, and potential side effects.

Risks & possible complications

  • Chemotherapy side effects: nausea, vomiting, hair loss, low blood cell counts (increasing infection risk), and kidney toxicity.
  • Neurotoxicity from treatment, potentially causing confusion, memory issues, or leukoencephalopathy (brain tissue changes).
  • Increased risk of infections, especially during periods of low white blood cell count.
  • Potential for delayed cognitive decline or neurological deficits, particularly with combined chemotherapy and radiation.
  • Complications related to the use of corticosteroids, such as high blood sugar, mood swings, and osteoporosis.

Recovery & hospital stay

  • Initial recovery involves close monitoring in the hospital for side effects, especially after high-dose chemotherapy cycles.
  • Regular follow-up MRI scans are essential to assess treatment response and monitor for recurrence.
  • Ongoing management of side effects and supportive care, which may include medications, blood transfusions, or growth factors.
  • Possible referral to physical, occupational, or speech therapy to address any neurological deficits.
  • Long-term follow-up with the oncology team for surveillance, as CNS lymphoma has a risk of recurrence.
  • Psychosocial support and counseling are often recommended for patients and caregivers.
  • checked Typical hospital stay: Varies widely per treatment cycle; initial intensive phase may require 5-10 days per hospitalization.
  • checked Expected recovery time: Several weeks to months for full recovery from a treatment cycle; long-term management is ongoing.

Frequently Asked Questions

If you are considering central nervous system lymphoma in India, these questions and answers can help you make a confident, informed decision.

Procedure cost in other countries

Here is an overview of how the estimated cost, hospital stay, and recovery time for central nervous system lymphoma compare across other countries where we have data.

Country Estimated cost range Typical stay Recovery time View details
India INR 350 Thousand – 1.2 Million Varies widely per treatment cycle; initial intensive phase may require 5-10 days per hospitalization. ~ Several weeks to months for full recovery from a treatment cycle; long-term management is ongoing. Know More
Turkey TRY 1.23 Million – 4.2 Million Varies widely per treatment cycle; initial intensive phase may require 5-10 days per hospitalization. ~ Several weeks to months for full recovery from a treatment cycle; long-term management is ongoing. Know More

Top hospitals for Central Nervous System Lymphoma in India

These partner hospitals in India have dedicated oncologist teams and experience managing patients undergoing central nervous system lymphoma.

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79+ Rating

Kamineni Hospital LB Nagar

  • IconHyderabad, India
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89+ Rating

Kamineni Hospital, Tadigadapa

  • Iconvijayawada, India
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15+ Rating

Manipal Hospital Mukundapur

  • IconKolkata, India
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43+ Rating

Manipal Hospital Dhakuria

  • IconKolkata, India
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2143+ Rating

Manipal Hospital Baner

  • IconPune, India
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432+ Rating

Manipal Hospital Gurgaon

  • IconGurgaon, India
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2478+ Rating

Manipal Hospital Jayanagar

  • IconBangalore, India
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1610+ Rating

Manipal Hospital Varthur Road

  • IconBangalore, India
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91+ Rating

Manipal Hospital Malleshwaram

  • IconBangalore, India
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6016+ Rating

Manipal Hospital Mysore

  • IconMysore, India
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1837+ Rating

Manipal Hospital Salem

  • IconSalem, India
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847+ Rating

Manipal Hospital Sarjapur Road

  • IconBangalore, India
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180+ Rating

Manipal Hospital Vijayawada

  • Iconvijayawada, India
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150+ Rating

Cytecare Hospital

  • IconBangalore, India
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2882+ Rating

Manipal Hospital Whitefield

  • IconBangalore, India
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534+ Rating

Manipal Hospital Yeshwanthpur

  • IconBangalore, India
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537+ Rating

Manipal Hospitals Broadway

  • IconKolkata, India
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10171+ Rating

Miot Hospital Chennai

  • IconChennai, India
  • Icon250 Doctors
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5734+ Rating

Manipal Hospital Siliguri

  • IconSiliguri, India
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89+ Rating

Manipal Hospital EM Bypass

  • IconKolkata, India
  • Icon94 Doctors
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89+ Rating

Manipal Hospital EM Bypass

  • IconKolkata, India
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65+ Rating

Manipal Hospital Salt Lake

  • IconKolkata, India
  • Icon129 Doctors
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12320+ Rating

Manipal Hospital Kanakapura Road

  • IconBangalore, India
  • Icon78 Doctors
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185+ Rating

Manipal Hospital Ranchi

  • IconRanchi, India
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872+ Rating

Manipal Hospital Millers Road

  • IconBangalore, India
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418+ Rating

Manipal Hospital Hebbal

  • IconBangalore, India
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1161+ Rating

Artemis Hospital Gurgaon

  • IconGurgaon, India
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694+ Rating

Manipal Hospital Kharadi

  • IconPune, India
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156+ Rating

Manipal Hospital Patiala

  • IconPatiala, India
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20+ Rating

Manipal Hospital Bhubaneswar

  • IconBhubaneshwar, India
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5740+ Rating

Manipal Hospital Old Airport Road

  • IconBangalore, India
  • Icon205 Doctors
PATIENT REVIEW

Karan Khan, a 58-year-old retired school...

Karan Khan, a 58-year-old retired school principal from Lahore, Pakistan, had always been the pillar of his family. Over several weeks, he began experiencing debilitating headaches, confusion, and a sudden, uncharacteristic difficulty finding words during conversations with his grandchildren. An MRI scan revealed a suspicious mass in his brain. His oncologist, Dr. Sharma, explained the findings and the need for a stereotactic brain biopsy to confirm a diagnosis of Primary Central Nervous System Lymphoma (PCNSL). Karan was terrified; the thought of brain surgery and a potential cancer diagnosis shook his deeply held identity as a protector. The biopsy procedure was daunting, but the medical team was reassuring. The diagnosis of PCNSL was confirmed. This led to a treatment plan of high-dose methotrexate chemotherapy. The recovery from the biopsy was swift, but the chemotherapy journey was arduous, marked by fatigue and nausea. Initially, Karan felt a profound sense of vulnerability and fear for his family's future. However, after his first few rounds of treatment showed a positive response on follow-up scans, his anxiety began to lift. He channeled his energy into his faith and family, finding strength in his role as a grandfather. While cautious, he now feels a guarded hope and is determined to witness more milestones in his family's life.

Oncologists for Central Nervous System Lymphoma

Explore experienced oncologists who regularly perform central nervous system lymphoma and provide pre- and post-operative care in India.

Dr. Senthil Kumar R
  • 10 Years Experience
  • Surgical Oncologist
Speaks: English, Tamil, Hindi
Consult Charge ₹ 900
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Miot Hospital Chennai, Chennai

OPD-desk synced • Updated
Dr. Kiran Kumar S
  • 4 Years Experience
  • Medical Oncologist
Speaks: English, Tamil, Hindi
Consult Charge ₹ 900
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Miot Hospital Chennai, Chennai

OPD-desk synced • Updated
Dr. Neelesh Reddy
  • 25 Years Experience
  • Oncologist
Speaks: English, Hindi
Consult Charge ₹ 900
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Yeshwanthpur, Bangalore

OPD-desk synced • Updated
Dr. Aravind Ramkumar
  • 19 Years Experience
  • Surgical Oncologist
Speaks: English, Hindi
Consult Charge ₹ 700
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Yeshwanthpur, Bangalore

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Dr. Mohammed Basheeruddin Inamdar
  • 11 Years Experience
  • Surgical Oncologist
Speaks: English, Hindi
Consult Charge ₹ 700
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Yeshwanthpur, Bangalore

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Dr. Roopa Sirigeri
  • 9 Years Experience
  • Oncologist
Speaks: English, Hindi
Consult Charge ₹ 600
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Yeshwanthpur, Bangalore

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Dr. Dharma Kumar K G
  • 16 Years Experience
  • Surgical Oncologist
Speaks: English, Hindi
Consult Charge ₹ 500
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Sarjapur Road, Bangalore

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Dr. Rohit
  • 11 Years Experience
  • Surgical Oncologist
Speaks: English, Hindi
Consult Charge ₹ 500
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Sarjapur Road, Bangalore

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Dr. Rohit Kumar C
  • 11 Years Experience
  • Surgical Oncologist
Speaks: English, Hindi
Consult Charge ₹ 450
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Whitefield, Bangalore

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Dr. Ashwin Rajagopal
  • 10 Years Experience
  • Surgical Oncologist
Speaks: English, Hindi
Consult Charge ₹ 800
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Whitefield, Bangalore

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Dr. Abhay Kumar
  • 15 Years Experience
  • Oncologist
Speaks: English, Hindi
Consult Charge ₹ 450
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Whitefield, Bangalore

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Dr. Amit Rauthan
  • 21 Years Experience
  • Oncologist
Speaks: English, Hindi
Consult Charge ₹ 1000
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Old Airport Road, Bangalore

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Dr. Shabber Zaveri
  • 33 Years Experience
  • Surgical Oncologist
Speaks: English, Hindi
Consult Charge ₹ 1000
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Old Airport Road, Bangalore

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Dr. Suraj Manjunath
  • 27 Years Experience
  • Oncologist
Speaks: English, Hindi
Consult Charge ₹ 1000
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Old Airport Road, Bangalore

OPD-desk synced • Updated
Dr. Poonam Patil
  • 30 Years Experience
  • Oncologist
Speaks: English, Hindi
Consult Charge ₹ 1000
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Old Airport Road, Bangalore

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Dr. Jayakarthik Y
  • 10 Years Experience
  • Surgical Oncologist
Speaks: English, Hindi
Consult Charge ₹ 700
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Mysore, Mysore

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Dr. Srinidhi M
  • 12 Years Experience
  • Surgical Oncologist
Speaks: English, Hindi
Consult Charge ₹ 800
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Mysore, Mysore

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Dr. G Krishna Reddy
  • 23 Years Experience
  • Oncologist
Speaks: English, Hindi
Consult Charge ₹ 800
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Vijayawada, vijayawada

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Dr. Sarat Chandra Pingali
  • 19 Years Experience
  • Surgical Oncologist
Speaks: English, Hindi
Consult Charge ₹ 850
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Vijayawada, vijayawada

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Dr. V Dharmendra Kumar
  • 17 Years Experience
  • Surgical Oncologist
Speaks: English, Hindi
Consult Charge ₹ 850
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Vijayawada, vijayawada

OPD-desk synced • Updated