About Diffuse Large B Cell Lymphoma
Key Highlights
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Highly effective first-line treatment for the most common aggressive lymphoma.Combination therapy (R-CHOP) targets cancer cells through multiple mechanisms.Treatment is typically administered in outpatient cycles, allowing for recovery between sessions.High cure rates, especially in early-stage disease.Personalized treatment plans based on specific genetic markers of the tumor.
Who is this surgery for?
- Confirmed diagnosis of Diffuse Large B-Cell Lymphoma via biopsy.
- Presence of symptoms such as rapid, painless lymph node swelling, fever, night sweats, unexplained weight loss, or fatigue.
- Disease that is localized (stage I/II) or advanced (stage III/IV).
- As a first-line therapy for newly diagnosed patients.
- For relapsed or refractory DLBCL, often with different chemotherapy regimens or stem cell transplant.
How to prepare
- Comprehensive diagnostic workup including biopsy, PET-CT scan, and blood tests.
- Cardiac evaluation (like an echocardiogram) due to potential effects of chemotherapy drugs.
- Dental check-up to prevent infections during immunosuppression.
- Fertility preservation counseling if of childbearing age.
- Insertion of a central venous catheter (port) for safe and easy drug administration.
- Discussion of the treatment plan, schedule, and management of side effects with the oncology team.
Risks & possible complications
- Chemotherapy side effects: nausea, vomiting, hair loss, fatigue, and increased risk of infections.
- Specific drug toxicities: heart damage from doxorubicin, nerve damage from vincristine.
- Low blood cell counts (neutropenia, anemia, thrombocytopenia) leading to infection, fatigue, or bleeding risk.
- Infusion reactions to rituximab.
- Long-term risks include secondary cancers or heart problems.
- Tumor lysis syndrome, a metabolic emergency caused by rapid cancer cell death.
Recovery & hospital stay
- Recovery occurs in cycles, with periods of fatigue and low immunity 7-14 days after each chemotherapy session.
- Regular blood tests are required to monitor cell counts.
- Prophylactic medications (anti-nausea, antibiotics, growth factors) are used to manage side effects.
- Patients must avoid sick contacts and practice meticulous hygiene to prevent infections.
- A follow-up PET-CT scan is performed mid-treatment and after completion to assess response.
- Long-term follow-up with the oncologist is essential to monitor for remission and late effects.
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Typical hospital stay: Mostly outpatient; 2-5 days for complications or transplant
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Expected recovery time: Varies per cycle; full course recovery 3-6 months
Frequently Asked Questions
If you are considering diffuse large b cell lymphoma in India, these questions and answers can help you make a confident, informed decision.
Popular choices for diffuse large b cell lymphoma in India include Miot Hospital Chennai, Cytecare Hospital, Kamineni Hospital LB Nagar, Kamineni Hospital, Tadigadapa, Manipal Hospital Old Airport Road, known for experienced specialists and advanced surgical infrastructure.
Look at the doctor’s years of experience, hospital association, patient reviews, and how often they perform diffuse large b cell lymphoma. MediFyr helps you compare oncologists and book consultations online.
The overall cost depends on hospital category, surgeon’s experience, room type, implant or device used (if any), length of stay, tests, and post-operative care. Our team can help you get cost estimates from multiple hospitals before you decide.
Procedure cost in other countries
Here is an overview of how the estimated cost, hospital stay, and recovery time for diffuse large b cell lymphoma compare across other countries where we have data.
| Country | Estimated cost range | Typical stay | Recovery time | View details |
|---|---|---|---|---|
| India | INR 300 Thousand – 1.5 Million | Mostly outpatient; 2-5 days for complications or transplant | ~ Varies per cycle; full course recovery 3-6 months | Know More |
| Turkey | TRY 1.05 Million – 5.25 Million | Mostly outpatient; 2-5 days for complications or transplant | ~ Varies per cycle; full course recovery 3-6 months | Know More |
Top hospitals for Diffuse Large B Cell Lymphoma in India
These partner hospitals in India have dedicated oncologist teams and experience managing patients undergoing diffuse large b cell lymphoma.
Rohan Kumar, a 58-year-old civil engineer...
Rohan Kumar, a 58-year-old civil engineer from Jaipur, had always been active and health-conscious. Over a few weeks, he developed a persistent, painless swelling in his neck that wouldn't go away, accompanied by drenching night sweats and profound fatigue that made it hard to complete his site inspections. His primary doctor ordered a biopsy of the swollen lymph node, which confirmed Diffuse Large B-Cell Lymphoma (DLBCL). His oncologist, Dr. Mehta, recommended a standard first-line treatment: six cycles of R-CHOP chemotherapy, explaining it was an aggressive but highly curable cancer with this regimen. Rohan experienced the expected side effects, nausea, hair loss, and significant fatigue, but managed them with supportive medications. After the third cycle, a PET scan showed a remarkable response, and by the end of treatment, he was in complete remission. Emotionally, Rohan was initially terrified, feeling his life and his ability to provide for his family were under threat. The support of his family and the clear progress seen on scans transformed his fear into determined hope. Post-recovery, he feels grateful and has channeled his experience into volunteering to support other newly diagnosed patients.
Oncologists for Diffuse Large B Cell Lymphoma
Explore experienced oncologists who regularly perform diffuse large b cell lymphoma and provide pre- and post-operative care in India.
- 10 Years Experience
- Surgical Oncologist
Miot Hospital Chennai, Chennai
- 4 Years Experience
- Medical Oncologist
Miot Hospital Chennai, Chennai
- 25 Years Experience
- Oncologist
Manipal Hospital Yeshwanthpur, Bangalore
- 19 Years Experience
- Surgical Oncologist
Manipal Hospital Yeshwanthpur, Bangalore
- 11 Years Experience
- Surgical Oncologist
Manipal Hospital Yeshwanthpur, Bangalore
- 9 Years Experience
- Oncologist
Manipal Hospital Yeshwanthpur, Bangalore
- 16 Years Experience
- Surgical Oncologist
Manipal Hospital Sarjapur Road, Bangalore
- 11 Years Experience
- Surgical Oncologist
Manipal Hospital Sarjapur Road, Bangalore
- 11 Years Experience
- Surgical Oncologist
Manipal Hospital Whitefield, Bangalore
- 10 Years Experience
- Surgical Oncologist
Manipal Hospital Whitefield, Bangalore
- 15 Years Experience
- Oncologist
Manipal Hospital Whitefield, Bangalore
- 21 Years Experience
- Oncologist
Manipal Hospital Old Airport Road, Bangalore
- 33 Years Experience
- Surgical Oncologist
Manipal Hospital Old Airport Road, Bangalore
- 27 Years Experience
- Oncologist
Manipal Hospital Old Airport Road, Bangalore
- 30 Years Experience
- Oncologist
Manipal Hospital Old Airport Road, Bangalore
- 10 Years Experience
- Surgical Oncologist
Manipal Hospital Mysore, Mysore
- 12 Years Experience
- Surgical Oncologist
Manipal Hospital Mysore, Mysore
- 23 Years Experience
- Oncologist
Manipal Hospital Vijayawada, vijayawada
- 19 Years Experience
- Surgical Oncologist
Manipal Hospital Vijayawada, vijayawada
- 17 Years Experience
- Surgical Oncologist
Manipal Hospital Vijayawada, vijayawada