About Molecular Oncology
Key Highlights
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Enables personalized cancer treatment based on the unique genetic makeup of the tumor.Identifies specific actionable mutations for targeted therapy, which can be more effective and have fewer side effects than traditional chemotherapy.Helps determine prognosis and disease progression more accurately.liCan identify patients who are eligible for strongclinical trials/strong of novel therapies./liliMay guide decisions on strongimmunotherapy/strong suitability by assessing biomarkers like PD-L1./liliOften performed on a strongtissue biopsy or liquid biopsy (blood sample)/strong, minimizing invasive procedures./li/ul
Who is this surgery for?
- Diagnosis of a new cancer to determine its molecular subtype and guide initial therapy.
- Progression or recurrence of cancer after standard treatment to identify new therapeutic targets.
- Cancers with known high prevalence of targetable mutations (e.g., non-small cell lung cancer, melanoma, breast cancer, colorectal cancer).
- When standard treatment options are limited or have been exhausted.
- To assess hereditary cancer risk through germline testing in certain familial cancer syndromes.
- To monitor treatment response and detect emerging resistance mutations through repeated testing.
How to prepare
- Consultation with an oncologist to discuss the goals, benefits, and limitations of molecular testing.
- Provision of a recent tumor tissue sample (from a biopsy or surgery) preserved in a specific way (formalin-fixed paraffin-embedded block).
- For a liquid biopsy, a simple blood draw is required, typically with no special fasting needed.
- Review of personal and family medical history to guide the selection of specific genes to test.
- Authorization and completion of necessary consent forms for genetic testing.
- Coordination with your insurance provider, as coverage for comprehensive molecular profiling can vary.
Risks & possible complications
- False positives or negatives: Test results may not always be conclusive or may misinterpret a genetic variant.
- Finding variants of uncertain significance (VUS): Discovering a genetic change whose impact on cancer risk or treatment is unknown, which can cause anxiety.
- Psychological impact: Learning about genetic mutations can be stressful for the patient and family members.
- Privacy concerns: Potential issues related to the storage and use of genetic information.
- Limited therapeutic options: Testing may identify a mutation for which no approved targeted drug is currently available.
- Sample inadequacy: The tumor sample may be insufficient in quantity or quality for accurate analysis.
Recovery & hospital stay
- If testing required a new biopsy, follow standard post-biopsy care (e.g., rest, monitoring the site for bleeding or infection).
- For a liquid biopsy (blood draw), there is typically no recovery time; normal activities can be resumed immediately.
- The primary recovery phase involves waiting for test results, which can take 2 to 4 weeks.
- Schedule a follow-up appointment with your oncologist to discuss the detailed molecular report and its implications for your treatment plan.
- Engage with genetic counselors if hereditary factors are identified, to understand risks for family members.
- Begin or adjust the personalized treatment plan as recommended by your oncology team based on the molecular findings.
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Typical hospital stay: 0 days (outpatient procedure)
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Expected recovery time: 0-2 days (if a biopsy is required for sample collection)
Frequently Asked Questions
If you are considering molecular oncology in India, these questions and answers can help you make a confident, informed decision.
Popular choices for molecular oncology in India include Miot Hospital Chennai, Cytecare Hospital, Kamineni Hospital LB Nagar, Kamineni Hospital, Tadigadapa, Manipal Hospital Old Airport Road, known for experienced specialists and advanced surgical infrastructure.
Look at the doctor’s years of experience, hospital association, patient reviews, and how often they perform molecular oncology. MediFyr helps you compare oncologists and book consultations online.
The overall cost depends on hospital category, surgeon’s experience, room type, implant or device used (if any), length of stay, tests, and post-operative care. Our team can help you get cost estimates from multiple hospitals before you decide.
Procedure cost in other countries
Here is an overview of how the estimated cost, hospital stay, and recovery time for molecular oncology compare across other countries where we have data.
| Country | Estimated cost range | Typical stay | Recovery time | View details |
|---|---|---|---|---|
| India | INR 20 Thousand – 150 Thousand | 0 days (outpatient procedure) | ~ 0-2 days (if a biopsy is required for sample collection) | Know More |
| Turkey | TRY 70 Thousand – 525 Thousand | 0 days (outpatient procedure) | ~ 0-2 days (if a biopsy is required for sample collection) | Know More |
Top hospitals for Molecular Oncology in India
These partner hospitals in India have dedicated oncologist teams and experience managing patients undergoing molecular oncology.
Sophia Brown, a 58-year-old elementary school...
Sophia Brown, a 58-year-old elementary school librarian and mother of three, had always been healthy. A persistent, dry cough she attributed to allergies lingered for months, followed by unexplained fatigue. A chest X-ray revealed a concerning mass in her lung. Terrified, as a non-smoker with no family history, she felt her world crumble. Her oncologist, Dr. Chen, recommended Molecular Oncology testing on her biopsy tissue. 'This isn't one-size-fits-all,' he explained. 'We need to look at the DNA of your specific cancer to find the right key.' The wait for the genomic profile results was agonizing; Sophia wrestled with fear and a sense of unfairness. The test revealed her tumor had a specific ALK gene rearrangement. Instead of standard chemotherapy, she started a targeted oral therapy designed to block the faulty ALK protein. The treatment experience was challenging with some side effects, but far less severe than she had feared. Six months later, follow-up scans showed significant tumor shrinkage. The emotional shift was profound. Sophia moved from feeling like a victim of a random, brutal disease to someone with a known adversary and a precise weapon. She regained a sense of agency and hope, returning part-time to her beloved library and planning a family trip she thought she'd never take.
Oncologists for Molecular Oncology
Explore experienced oncologists who regularly perform molecular oncology and provide pre- and post-operative care in India.
- 10 Years Experience
- Surgical Oncologist
Miot Hospital Chennai, Chennai
- 4 Years Experience
- Medical Oncologist
Miot Hospital Chennai, Chennai
- 25 Years Experience
- Oncologist
Manipal Hospital Yeshwanthpur, Bangalore
- 19 Years Experience
- Surgical Oncologist
Manipal Hospital Yeshwanthpur, Bangalore
- 11 Years Experience
- Surgical Oncologist
Manipal Hospital Yeshwanthpur, Bangalore
- 9 Years Experience
- Oncologist
Manipal Hospital Yeshwanthpur, Bangalore
- 16 Years Experience
- Surgical Oncologist
Manipal Hospital Sarjapur Road, Bangalore
- 11 Years Experience
- Surgical Oncologist
Manipal Hospital Sarjapur Road, Bangalore
- 11 Years Experience
- Surgical Oncologist
Manipal Hospital Whitefield, Bangalore
- 10 Years Experience
- Surgical Oncologist
Manipal Hospital Whitefield, Bangalore
- 15 Years Experience
- Oncologist
Manipal Hospital Whitefield, Bangalore
- 21 Years Experience
- Oncologist
Manipal Hospital Old Airport Road, Bangalore
- 33 Years Experience
- Surgical Oncologist
Manipal Hospital Old Airport Road, Bangalore
- 27 Years Experience
- Oncologist
Manipal Hospital Old Airport Road, Bangalore
- 30 Years Experience
- Oncologist
Manipal Hospital Old Airport Road, Bangalore
- 10 Years Experience
- Surgical Oncologist
Manipal Hospital Mysore, Mysore
- 12 Years Experience
- Surgical Oncologist
Manipal Hospital Mysore, Mysore
- 23 Years Experience
- Oncologist
Manipal Hospital Vijayawada, vijayawada
- 19 Years Experience
- Surgical Oncologist
Manipal Hospital Vijayawada, vijayawada
- 17 Years Experience
- Surgical Oncologist
Manipal Hospital Vijayawada, vijayawada