Neonatal Herpes Type 1 Virus Treatment in India

Olivia Smith is a 3-week-old infant,...

Olivia Smith is a 3-week-old infant, born full-term via uncomplicated vaginal delivery to first-time parents. At 10 days old, Olivia developed clusters of small, fluid-filled blisters around her mouth and on her cheek. Her parents, initially thinking it was baby acne or a rash from drooling, grew concerned when the blisters multiplied and Olivia became fussy, refused feeds, and developed a low-grade fever. Their pediatrician, suspecting neonatal herpes, urgently referred them to a pediatric dermatologist. The dermatologist explained that while Olivia's mother had no history of cold sores, the virus could have been transmitted asymptomatically during birth or by a visitor. A PCR swab of the blister fluid confirmed HSV-1. Olivia was immediately hospitalized and started on intravenous acyclovir. The treatment was intense, with frequent blood draws to monitor her kidney function. After 21 days of IV treatment, the blisters crusted over and healed without scarring. Olivia's parents rode an emotional rollercoaster from initial confusion and guilt ('Did we do something wrong?') to terror at the diagnosis, and finally to profound relief and vigilance. They now are hyper-aware of hand hygiene and ask anyone with any sign of a cold sore to avoid close contact.