About PAS Stain
Key Highlights
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Highly specific for detecting carbohydrates like glycogen and mucins in tissues.Essential for diagnosing fungal infections (e.g., Candida, Aspergillus) in biopsy samples.Critical for identifying basement membrane abnormalities in kidney diseases like Alport syndrome.Aids in the diagnosis of glycogen storage diseases (e.g., Pompe disease).Helps characterize certain tumors, especially those producing mucus (adenocarcinomas).Provides clear, vivid staining that enhances microscopic visualization for pathologists./ul
Who is this surgery for?
- Suspected fungal infections in tissue biopsies (e.g., lung, skin, gastrointestinal tract).
- Evaluation of kidney biopsy for diseases affecting the glomerular basement membrane.
- Diagnosis of glycogen storage disorders from liver or muscle biopsies.
- Identification and classification of adenocarcinomas and other mucus-producing tumors.
- Assessment of certain inflammatory bowel diseases where mucin patterns are altered.
- Detection of organisms like Tropheryma whipplei in Whipple's disease.
How to prepare
- The procedure is performed on a tissue sample already obtained via biopsy or surgery; no direct patient preparation is needed.
- The tissue sample must be properly fixed (usually in formalin), processed, embedded in paraffin, and thinly sectioned onto a glass slide.
- The pathologist or histotechnologist ensures the slide is deparaffinized and rehydrated through a series of alcohol solutions.
- All necessary reagents (periodic acid, Schiff's reagent, counterstains) are prepared and quality-checked.
Risks & possible complications
- There are no direct physical risks to the patient as the stain is applied to an already-collected tissue sample.
- Potential for false-positive or false-negative results due to technical issues like over-oxidation or degraded reagents.
- Interpretation risk: Requires expert pathological analysis; misinterpretation could lead to an incorrect diagnosis.
- Sample risk: If the original biopsy was non-representative, the stain results may not reflect the overall disease state.
Recovery & hospital stay
- There is no patient recovery process, as the PAS stain is a laboratory procedure performed on tissue.
- Post-procedure care involves the pathologist interpreting the stained slide and integrating findings into a comprehensive pathology report.
- The patient's recovery depends on the underlying condition for which the biopsy was taken and its subsequent treatment.
- Patients should follow up with their referring doctor to discuss the pathology report results and next steps.
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Typical hospital stay: 0 days
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Expected recovery time: Not applicable
Frequently Asked Questions
If you are considering pas stain in India, these questions and answers can help you make a confident, informed decision.
Top-rated hospitals in India with pathology departments and experienced surgeons are ideal for this procedure. Use MediFyr to compare facilities, reviews, and doctor profiles before you decide.
Look at the doctor’s years of experience, hospital association, patient reviews, and how often they perform pas stain. MediFyr helps you compare pathologist specialists and book consultations online.
The overall cost depends on hospital category, surgeon’s experience, room type, implant or device used (if any), length of stay, tests, and post-operative care. Our team can help you get cost estimates from multiple hospitals before you decide.
Procedure cost in other countries
Here is an overview of how the estimated cost, hospital stay, and recovery time for pas stain compare across other countries where we have data.
Myra Nair, a 58-year-old retired librarian,...
Myra Nair, a 58-year-old retired librarian, had been experiencing persistent fatigue, unexplained weight loss, and occasional abdominal pain for several months. Her primary care physician noted elevated liver enzymes in routine bloodwork. Concerned about potential liver disease, her doctor referred her to a hepatologist who recommended a liver biopsy. The biopsy tissue was sent for a PAS stain, a special test to look for abnormal glycogen storage or specific fungal infections. Myra was anxious, fearing a cancer diagnosis. The procedure itself was a waiting game; she didn't experience the stain, but waited days for the pathologist's report. The PAS stain revealed Lafora bodies, leading to a diagnosis of Lafora disease, a rare genetic glycogen storage disorder. While the diagnosis was serious, it provided a clear answer and directed her to a neurologist for specific management. Myra felt a grim relief, the unknown was finally known, allowing her and her family to focus on treatment and support.
Pathologist Specialists for PAS Stain
Explore experienced pathologist specialists who regularly perform pas stain and provide pre- and post-operative care in India.
- 33 Years Experience
- Pathologist Specialist
Kamineni Hospital, King Koti, Hyderabad
- 33 Years Experience
- Pathologist Specialist
Kamineni Hospital, King Koti, Hyderabad
- 32 Years Experience
- Pathologist Specialist
Kamineni Hospital LB Nagar, Hyderabad
- 29 Years Experience
- Pathologist Specialist
Kamineni Hospital, Tadigadapa, vijayawada
- 29 Years Experience
- Pathologist Specialist
Kamineni Hospital, King Koti, Hyderabad
- 27 Years Experience
- Pathologist Specialist
Kamineni Hospital, Tadigadapa, vijayawada
- 23 Years Experience
- Pathologist Specialist
Metro Hospital, Sector 11, Noida
- 21 Years Experience
- Pathologist Specialist
Kamineni Hospital, Tadigadapa, vijayawada
- 20 Years Experience
- Pathologist Specialist
Kamineni Hospital LB Nagar, Hyderabad
- 20 Years Experience
- Pathologist Specialist
Kamineni Hospital, King Koti, Hyderabad
- 19 Years Experience
- Pathologist Specialist
Kamineni Hospital LB Nagar, Hyderabad
- 19 Years Experience
- Pathologist Specialist
Kamineni Hospital LB Nagar, Hyderabad
- 18 Years Experience
- Pathologist Specialist
Metro Hospital, Sector 11, Noida
- 18 Years Experience
- Pathologist Specialist
Kamineni Hospital, King Koti, Hyderabad
- 18 Years Experience
- Pathologist Specialist
Kamineni Hospital LB Nagar, Hyderabad
- 15 Years Experience
- Pathologist Specialist
Kamineni Hospital LB Nagar, Hyderabad
- 13 Years Experience
- Pathologist Specialist
Kamineni Hospital LB Nagar, Hyderabad
- 10 Years Experience
- Pathologist Specialist
Kamineni Hospital, King Koti, Hyderabad
- 6 Years Experience
- Pathologist Specialist
Kamineni Hospital LB Nagar, Hyderabad
- 22 Years Experience
- Pathologist Specialist
Manipal Hospital Jaipur, Jaipur