Learn about Pernicious Anemia Treatment in India — how it works, who it is for, recovery timelines, and what to expect before and after surgery. Compare hospitals and doctors experienced in Pernicious Anemia and request assistance for cost estimates or appointments.

About Pernicious Anemia

Pernicious anemia is not a procedure but a medical condition, specifically a type of vitamin B12 deficiency anemia caused by an autoimmune attack on the stomach lining, which prevents the absorption of this crucial vitamin. An Internal Medicine specialist manages this lifelong condition through a comprehensive diagnostic and therapeutic process. This involves confirming the diagnosis via blood tests (like B12 levels, intrinsic factor antibodies, and a complete blood count) and often an endoscopic evaluation of the stomach. The cornerstone of treatment is regular, lifelong vitamin B12 replacement therapy, typically administered via intramuscular injections or high-dose oral supplements, to replenish stores, correct anemia, and prevent irreversible neurological damage. Management also includes monitoring for other associated autoimmune conditions.

Key Highlights

    Effective reversal of anemia and its associated symptoms like fatigue and shortness of breath.Prevention of serious, potentially irreversible neurological complications (e.g., nerve damage, memory problems).Lifelong but straightforward management plan primarily involving regular B12 supplementation.Non-surgical, medical management overseen by an Internal Medicine specialist.Can significantly improve quality of life and long-term health outcomes.

Who is this surgery for?

  • Presence of macrocytic anemia (enlarged red blood cells) on a complete blood count (CBC).
  • Symptoms of anemia such as severe fatigue, weakness, pale skin, dizziness, and shortness of breath.
  • Neurological symptoms suggestive of B12 deficiency, including numbness, tingling in hands/feet, balance problems, memory loss, or mood changes.
  • A positive test for intrinsic factor antibodies or parietal cell antibodies.
  • Findings of atrophic gastritis (thinning stomach lining) on endoscopy, often associated with the condition.
  • History of autoimmune disorders (e.g., thyroid disease, type 1 diabetes) which increase risk.

How to prepare

  • Detailed medical history review and physical examination by the Internal Medicine doctor.
  • Completion of initial blood tests, including a Complete Blood Count (CBC), vitamin B12 level, and folate level.
  • Fasting may be required for certain follow-up blood tests (like methylmalonic acid or homocysteine).
  • For diagnostic endoscopy, patients will need to follow specific pre-procedure fasting and medication instructions.
  • Discussion of symptoms, family history, and any current medications with the physician.

Risks & possible complications

  • If left untreated, risk of permanent neurological damage, including neuropathy, ataxia, and cognitive decline.
  • Potential for complications from untreated anemia, such as heart problems (tachycardia, heart failure).
  • Risks associated with B12 injections are minimal but can include pain or redness at the injection site, mild itching, or rare allergic reactions.
  • High-dose oral B12 supplements are generally very safe but may cause mild gastrointestinal upset in some individuals.
  • Delay in diagnosis can lead to worsening of symptoms and more complex recovery.

Recovery & hospital stay

  • Initial response to B12 therapy is often rapid, with improvement in energy levels within days to weeks.
  • Neurological symptoms may take longer to improve (months) and some damage may be irreversible if treatment was delayed.
  • Commitment to lifelong, regular B12 supplementation (injections every 1-3 months or daily high-dose oral tablets) as prescribed.
  • Regular follow-up blood tests to monitor B12 levels, red blood cell counts, and treatment efficacy.
  • No specific activity restrictions; patients are encouraged to resume normal activities as energy levels permit.
  • Ongoing monitoring for the development of other autoimmune conditions is recommended.
  • checked Typical hospital stay: 0 days (Outpatient management)
  • checked Expected recovery time: Ongoing management; symptomatic improvement in 2-6 weeks

Frequently Asked Questions

If you are considering pernicious anemia in India, these questions and answers can help you make a confident, informed decision.

Procedure cost in other countries

Here is an overview of how the estimated cost, hospital stay, and recovery time for pernicious anemia compare across other countries where we have data.

Country Estimated cost range Typical stay Recovery time View details
India INR 5 Thousand – 25 Thousand 0 days (Outpatient management) ~ Ongoing management; symptomatic improvement in 2-6 weeks Know More
Turkey TRY 17.5 Thousand – 87.5 Thousand 0 days (Outpatient management) ~ Ongoing management; symptomatic improvement in 2-6 weeks Know More

Top hospitals for Pernicious Anemia in India

These partner hospitals in India have dedicated internal medicine teams and experience managing patients undergoing pernicious anemia.

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Manipal Hospital Ghaziabad

  • IconGhaziabad, India
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91+ Rating

Manipal Hospital Malleshwaram

  • IconBangalore, India
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5734+ Rating

Manipal Hospital Siliguri

  • IconSiliguri, India
  • Icon30 Doctors
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89+ Rating

Manipal Hospital EM Bypass

  • IconKolkata, India
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65+ Rating

Manipal Hospital Salt Lake

  • IconKolkata, India
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12320+ Rating

Manipal Hospital Kanakapura Road

  • IconBangalore, India
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185+ Rating

Manipal Hospital Ranchi

  • IconRanchi, India
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1161+ Rating

Artemis Hospital Gurgaon

  • IconGurgaon, India
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181+ Rating

KMC Hospital Mangalore

  • IconMangalore, India
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PATIENT REVIEW

Pari Kumar, a 58-year-old retired school...

Pari Kumar, a 58-year-old retired school librarian from a traditional South Indian vegetarian family, had been feeling increasingly unwell for over a year. She experienced profound fatigue, making her daily walks and volunteer work impossible. She felt a constant 'pins and needles' sensation in her hands and feet, and her balance had become unsteady. Her primary care physician initially attributed it to aging and stress. When her symptoms worsened, including a swollen, beefy-red tongue and episodes of confusion, her daughter insisted on a specialist referral. An Internal Medicine specialist, Dr. Chen, listened carefully to her history, noting her strict lifelong vegetarianism. He suspected a B12 deficiency and ordered blood tests, which revealed macrocytic anemia and critically low B12 levels. A positive intrinsic factor antibody test confirmed Pernicious Anemia. Dr. Chen explained that her body was attacking the cells in her stomach that make a protein needed to absorb B12. He recommended starting lifelong intramuscular B12 injections. Pari was terrified of needles but desperate for relief. Her first injection was administered in the clinic. Within two weeks, the brain fog began to lift and her energy slowly returned. The neurological symptoms took months to improve but did so gradually. After six months of monthly injections, Pari regained her balance and most of the sensation in her limbs. Emotionally, she moved from a place of fear and frustration, feeling like her body was betraying her, to one of empowerment and gratitude. She now views her monthly injection as a simple, life-giving ritual and has returned to her community activities with renewed vigor.

Internal Medicine Specialists for Pernicious Anemia

Explore experienced internal medicine specialists who regularly perform pernicious anemia and provide pre- and post-operative care in India.

Dr. Geetha K Subramaniyam K
  • 41 Years Experience
  • Internal Medicine Specialist
Speaks: English, Hindi
Consult Charge ₹ 600
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Yeshwanthpur, Bangalore

OPD-desk synced • Updated
Dr. Sangeshwaran
  • 11 Years Experience
  • Internal Medicine Specialist
Speaks: English, Hindi
Consult Charge ₹ 500
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Salem, Salem

OPD-desk synced • Updated
Dr. Archana D
  • 8 Years Experience
  • Internal Medicine Specialist
Speaks: English, Hindi
Consult Charge ₹ 450
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Salem, Salem

OPD-desk synced • Updated
Dr. Arun Karthik P
  • 8 Years Experience
  • Internal Medicine Specialist
Speaks: English, Hindi
Consult Charge ₹ 450
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Salem, Salem

OPD-desk synced • Updated
Dr. C Harish
  • 8 Years Experience
  • Internal Medicine Specialist
Speaks: English, Hindi
Consult Charge ₹ 500
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Salem, Salem

OPD-desk synced • Updated
Dr. Veerendra B Sutar
  • 22 Years Experience
  • Internal Medicine Specialist
Speaks: English, Hindi
Consult Charge ₹ 450
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Whitefield, Bangalore

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Dr. Ravi Kumar
  • 16 Years Experience
  • Internal Medicine Specialist
Speaks: English, Hindi
Consult Charge ₹ 450
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Whitefield, Bangalore

OPD-desk synced • Updated
Dr. Reshu Agrawal
  • 15 Years Experience
  • Internal Medicine Specialist
Speaks: English, Hindi
Consult Charge ₹ 500
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Whitefield, Bangalore

OPD-desk synced • Updated
Dr. Sanjiv Rao
  • 32 Years Experience
  • Internal Medicine Specialist
Speaks: English, Hindi
Consult Charge ₹ 850
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Old Airport Road, Bangalore

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Dr. Prashant Bhatt
  • 18 Years Experience
  • Internal Medicine Specialist
Speaks: English, Hindi
Consult Charge ₹ 900
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Patiala, Patiala

OPD-desk synced • Updated
Dr. Gurpreet Singh Dang
  • 14 Years Experience
  • Internal Medicine Specialist
Speaks: English, Hindi
Consult Charge ₹ 900
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Patiala, Patiala

OPD-desk synced • Updated
Dr. Inderjeet Kaur
  • 8 Years Experience
  • Internal Medicine Specialist
Speaks: English, Hindi
Consult Charge ₹ 450
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Patiala, Patiala

OPD-desk synced • Updated
Dr. K Sriram
  • 13 Years Experience
  • Internal Medicine Specialist
Speaks: English, Hindi
Consult Charge ₹ 900
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Vijayawada, vijayawada

OPD-desk synced • Updated
Dr. HARIKA UPPALAPATI
  • 9 Years Experience
  • Internal Medicine Specialist
Speaks: English, Hindi
Consult Charge ₹ 850
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Vijayawada, vijayawada

OPD-desk synced • Updated
Dr. Sharada Shekar
  • 43 Years Experience
  • Internal Medicine Specialist
Speaks: English, Hindi
Consult Charge ₹ 850
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Malleshwaram, Bangalore

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Dr. Dinesh Kamath
  • 36 Years Experience
  • Internal Medicine Specialist
Speaks: English, Hindi
Consult Charge ₹ 850
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Malleshwaram, Bangalore

OPD-desk synced • Updated
Dr. Basavaraj Kuntoji
  • 23 Years Experience
  • Internal Medicine Specialist
Speaks: English, Hindi
Consult Charge ₹ 650
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Malleshwaram, Bangalore

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Dr. Arun Suradkar
  • 23 Years Experience
  • Internal Medicine Specialist
Speaks: English, Hindi
Consult Charge ₹ 650
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Kharadi, Pune

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Dr. Vichar Shyam Nigam
  • 21 Years Experience
  • Internal Medicine Specialist
Speaks: English, Hindi
Consult Charge ₹ 550
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Kharadi, Pune

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Dr. Vijay Narasappa Talkad
  • 15 Years Experience
  • Internal Medicine Specialist
Speaks: English, Hindi
Consult Charge ₹ 650
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Jayanagar, Bangalore

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