Plasma Exchange Treatment in India – Best Hospitals & Doctors

Learn about Plasma Exchange Treatment in India — how it works, who it is for, recovery timelines, and what to expect before and after surgery. Compare hospitals and doctors experienced in Plasma Exchange and request assistance for cost estimates or appointments.

Partner Hospitals

0 partner in India for this surgery

Specialist Doctors

8 Surgeons linked to this surgery

Treatment Cost

Approx INR 25 Thousand – 75 Thousand

About Plasma Exchange

Plasma Exchange, also known as Therapeutic Plasma Exchange (TPE) or Plasmapheresis, is a specialized medical procedure performed by Transfusion Medicine specialists. It involves the removal, treatment, and return of a patient's blood plasma. During the procedure, blood is drawn from the body, separated into its cellular components and plasma by a cell separator machine. The harmful plasma, which may contain disease-causing antibodies, toxins, or abnormal proteins, is discarded and replaced with a substitute like donor plasma or a sterile albumin solution. This process effectively 'cleanses' the blood and is a critical, life-saving intervention for managing various autoimmune, neurological, and metabolic disorders by rapidly removing pathogenic substances from the bloodstream.

Key Highlights

Rapidly removes harmful antibodies, toxins, or abnormal proteins from the bloodstream.Can be a life-saving intervention during acute disease flares or crises.Used as a primary treatment or to 'bridge' the time until other medications become effective.Performed by specialized Transfusion Medicine teams ensuring safety and precision.Procedure is typically well-tolerated and can be repeated as needed based on the condition.

Who is this surgery for?

Neurological disorders like Guillain-Barré Syndrome, Myasthenia Gravis, and Chronic Inflammatory Demyelinating Polyneuropathy (CIDP).
Autoimmune conditions such as Goodpasture's syndrome, ANCA-associated vasculitis, and severe Lupus.
Hematological diseases including Thrombotic Thrombocytopenic Purpura (TTP) and Hyperviscosity syndrome.
Certain kidney diseases like rapidly progressive glomerulonephritis.
Poisoning or overdose with protein-bound toxins (e.g., from certain mushrooms).
As a preparatory procedure before some organ or stem cell transplants.

How to prepare

A thorough medical evaluation, including blood tests to assess clotting function and electrolyte levels.
Discussion of medical history, allergies (especially to plasma products), and current medications.
Establishment of secure intravenous (IV) access, often with a large-bore catheter in a major vein.
Patients are advised to be well-hydrated before the procedure.
Fasting is generally not required, but a light meal is recommended.
Informed consent detailing the procedure, benefits, and potential risks is obtained.

Risks & possible complications

Hypotension (low blood pressure) or dizziness during the procedure.
Citrate reaction from the anticoagulant, causing tingling or muscle cramps.
Allergic reactions to the replacement fluid (plasma or albumin).
Bleeding or bruising at the IV site, or infection.
Risk of electrolyte imbalances like low calcium or potassium.
Very rare risks include blood clot formation or air embolism.

Recovery & hospital stay

Immediate monitoring of vital signs for an hour or two post-procedure.
Patients can usually resume normal activities and diet shortly after, unless otherwise advised.
It is important to drink plenty of fluids to help maintain blood volume.
The IV site should be kept clean and dry; report any signs of redness, swelling, or pain.
Follow-up blood tests are common to monitor the disease and the effects of the exchange.
Multiple sessions over days or weeks are often required for optimal therapeutic effect.

Typical hospital stay: Typically outpatient or 1 day
Expected recovery time: Immediate to a few days (per session)

Frequently Asked Questions

If you are considering plasma exchange in India, these questions and answers can help you make a confident, informed decision.

＋ − Which hospitals are best for plasma exchange in India?

Top-rated hospitals in India with transfusion medicine departments and experienced surgeons are ideal for this procedure. Use MediFyr to compare facilities, reviews, and doctor profiles before you decide.

＋ − How do I choose the right doctor for plasma exchange?

Look at the doctor’s years of experience, hospital association, patient reviews, and how often they perform plasma exchange. MediFyr helps you compare transfusion medicine specialists and book consultations online.

＋ − What factors affect the cost of plasma exchange?

The overall cost depends on hospital category, surgeon’s experience, room type, implant or device used (if any), length of stay, tests, and post-operative care. Our team can help you get cost estimates from multiple hospitals before you decide.

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Procedure cost in other countries

Here is an overview of how the estimated cost, hospital stay, and recovery time for plasma exchange compare across other countries where we have data.

Country	Estimated cost range	Typical stay	Recovery time	View details
India	INR 25 Thousand – 75 Thousand	Typically outpatient or 1 day	~ Immediate to a few days (per session)	Know More
Turkey	TRY 87.5 Thousand – 263 Thousand	Typically outpatient or 1 day	~ Immediate to a few days (per session)	Know More

PATIENT REVIEW

Arjun Sharma, a 42-year-old software engineer...

Arjun Sharma, a 42-year-old software engineer and father of two, had always been active. His life changed when he developed sudden, severe weakness in his legs, which rapidly spread to his arms and face. Diagnosed with Guillain-Barré Syndrome, his immune system was attacking his own nerves. Within days, he was in the ICU, struggling to breathe on his own. His neurologist, Dr. Mehta, explained that plasma exchange (PLEX) was critical to 'clean' his blood of the harmful antibodies causing the paralysis. Arjun was terrified, feeling trapped in his own failing body. The procedure itself was surreal, watching his blood travel through the apheresis machine, feeling cold from the replacement fluids. He underwent five sessions over ten days. Gradually, the tingling stopped, and he could wiggle his toes. The emotional shift was profound, from the despair of possibly never walking his daughters to school again, to the overwhelming gratitude as he took his first assisted steps. While recovery took months of physiotherapy, PLEX gave him back the chance to fight.