About Preimplantation Genetic Screening
Key Highlights
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Increases the likelihood of a successful pregnancy and live birth from an IVF cycle.Reduces the risk of miscarriage associated with chromosomal abnormalities.Helps in selecting the healthiest embryo for transfer, improving IVF efficiency.Can decrease the time to achieve a successful pregnancy by avoiding transfers of non-viable embryos.Provides valuable information for family planning, especially for couples with genetic concerns.
Who is this surgery for?
- Advanced maternal age (typically 35 years and older).
- History of recurrent pregnancy loss (miscarriages).
- Previous failed IVF implantation attempts.
- Severe male factor infertility.
- Carriers of chromosomal rearrangements (e.g., translocations).
- Desire for single embryo transfer to reduce the risk of multiple pregnancies.
How to prepare
- Complete fertility evaluation and counseling with a reproductive specialist.
- Standard IVF preparation, including ovarian stimulation and monitoring.
- Egg retrieval procedure to collect oocytes.
- Fertilization of eggs with sperm in the lab to create embryos.
- Embryo culture for 5-6 days until they reach the blastocyst stage.
- Genetic counseling to understand the process, benefits, and limitations of PGS.
Risks & possible complications
- Risk of embryo damage during the biopsy procedure to remove cells for testing.
- No embryos may be found suitable for transfer after screening (all aneuploid).
- Possibility of false-positive or false-negative results, though rare with modern techniques.
- Does not screen for all genetic diseases or structural birth defects.
- Adds additional cost and time to the standard IVF process.
Recovery & hospital stay
- Physical recovery from the egg retrieval procedure is typically quick, within 1-2 days.
- Patients can usually resume normal, non-strenuous activities the day after retrieval.
- Awaiting PGS results takes approximately 1-2 weeks; during this time, embryos are vitrified (frozen).
- Once a euploid embryo is identified, a frozen embryo transfer (FET) cycle is planned.
- Post-transfer, patients are advised to avoid strenuous activity and follow medication protocols (like progesterone support) as prescribed.
- A pregnancy test is scheduled about 10-14 days after the embryo transfer.
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Typical hospital stay: 0 days (Outpatient procedure for biopsy; egg retrieval may require a few hours at the clinic)
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Expected recovery time: 1-2 days (from egg retrieval); the overall cycle spans several weeks
Frequently Asked Questions
If you are considering preimplantation genetic screening in India, these questions and answers can help you make a confident, informed decision.
Top-rated hospitals in India with ivf and reproductive medicine departments and experienced surgeons are ideal for this procedure. Use MediFyr to compare facilities, reviews, and doctor profiles before you decide.
Look at the doctor’s years of experience, hospital association, patient reviews, and how often they perform preimplantation genetic screening. MediFyr helps you compare ivf and reproductive medicines and book consultations online.
The overall cost depends on hospital category, surgeon’s experience, room type, implant or device used (if any), length of stay, tests, and post-operative care. Our team can help you get cost estimates from multiple hospitals before you decide.
Procedure cost in other countries
Here is an overview of how the estimated cost, hospital stay, and recovery time for preimplantation genetic screening compare across other countries where we have data.
| Country | Estimated cost range | Typical stay | Recovery time | View details |
|---|---|---|---|---|
| India | INR 150 Thousand – 350 Thousand | 0 days (Outpatient procedure for biopsy; egg retrieval may require a few hours at the clinic) | ~ 1-2 days (from egg retrieval); the overall cycle spans several weeks | Know More |
| Turkey | TRY 525 Thousand – 1.23 Million | 0 days (Outpatient procedure for biopsy; egg retrieval may require a few hours at the clinic) | ~ 1-2 days (from egg retrieval); the overall cycle spans several weeks | Know More |
Navya Smith, 38, is a software...
Navya Smith, 38, is a software engineer who always envisioned a large family. After three heartbreaking miscarriages in two years, each occurring between 8-10 weeks, she and her husband felt emotionally shattered. Testing revealed Navya had a balanced chromosomal translocation, meaning her embryos had a high chance of being chromosomally abnormal, leading to the recurrent losses. Her reproductive endocrinologist recommended IVF with Preimplantation Genetic Screening (PGS) to identify embryos with the correct number of chromosomes before transfer. The IVF process was physically demanding, but the two-week wait for the PGS results was the most agonizing part. The news that two of their five embryos were chromosomally normal was a profound relief. They transferred one, and Navya is now 14 weeks pregnant, with early scans showing a healthy, developing baby. The emotional journey shifted from grief and fear of another loss to cautious hope and a sense of regained control over their family-building journey.
IVF and Reproductive Medicines for Preimplantation Genetic Screening
Explore experienced ivf and reproductive medicines who regularly perform preimplantation genetic screening and provide pre- and post-operative care in India.
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