Learn about Stiff Man Syndrome Treatment in India — how it works, who it is for, recovery timelines, and what to expect before and after surgery. Compare hospitals and doctors experienced in Stiff Man Syndrome and request assistance for cost estimates or appointments.

About Stiff Man Syndrome

Stiff Person Syndrome (SPS) is a rare and complex neurological disorder characterized by progressive muscle stiffness and painful spasms, primarily affecting the trunk and limbs. A neurologist manages this condition through a comprehensive diagnostic and therapeutic approach, as there is no single curative procedure. Diagnosis involves a detailed clinical evaluation, blood tests to detect specific autoantibodies (like anti-GAD65), electromyography (EMG) to assess muscle activity, and sometimes a lumbar puncture. Treatment is multifaceted and personalized, focusing on symptom control and improving quality of life. It typically involves a combination of medications such as muscle relaxants (e.g., baclofen), anti-anxiety drugs (e.g., diazepam), and immunotherapies (like intravenous immunoglobulin or plasmapheresis) to modulate the immune system. Ongoing neurological care is essential for monitoring disease progression and adjusting the treatment plan.

Key Highlights

    Provides a definitive diagnosis for a rare and often misdiagnosed condition.Offers a personalized, multi-modal treatment plan to manage symptoms.Focuses on improving mobility, reducing pain, and enhancing overall quality of life.Involves specialized neurological expertise for accurate assessment and long-term management.May incorporate advanced immunotherapies to target the underlying autoimmune process.

Who is this surgery for?

  • Progressive muscle stiffness and rigidity, especially in the trunk and proximal limbs.
  • Episodes of severe, painful muscle spasms triggered by stress, sudden movement, or noise.
  • Abnormal, hunched-over posture (hyperlordosis) due to continuous muscle contraction.
  • Difficulty walking or frequent falls due to stiffness and spasms.
  • Presence of other autoimmune conditions (e.g., type 1 diabetes, thyroiditis) which are common comorbidities.

How to prepare

  • Detailed neurological consultation to review full medical history and symptoms.
  • Blood tests to check for anti-GAD65 antibodies and other autoimmune markers.
  • Electromyography (EMG) and nerve conduction studies may be scheduled.
  • Discussion of current medications and potential adjustments prior to starting new therapies.
  • For procedures like IVIG or plasmapheresis, pre-treatment blood work and vital sign checks are required.
  • Psychological preparation, as stress management is a key component of care.

Risks & possible complications

  • Side effects from medications, including drowsiness, dizziness, dependency, or liver function changes.
  • Risks associated with immunotherapies: allergic reactions, headaches, flu-like symptoms, or infection (IVIG).li>
  • Complications from plasmapheresis: low blood pressure, bleeding, or electrolyte imbalance.
  • Potential for disease progression or treatment-resistant symptoms.
  • Increased risk of falls and related injuries due to muscle stiffness and spasms.

Recovery & hospital stay

  • Treatment is chronic and focuses on long-term management rather than a single recovery period.
  • Medication effects and dosages are carefully titrated over weeks to months for optimal control.
  • Regular follow-up appointments with the neurologist are crucial to monitor response and adjust therapy.
  • Physical therapy is often recommended to maintain flexibility, strength, and safe mobility.
  • Psychological support or counseling can help manage the emotional impact and stress triggers.
  • Patients learn to identify and avoid personal triggers for spasms.
  • checked Typical hospital stay: 0-3 days (typically outpatient for diagnostics; inpatient may be required for initiating certain immunotherapies)
  • checked Expected recovery time: Ongoing management; initial symptom control may take several weeks to months

Frequently Asked Questions

If you are considering stiff man syndrome in India, these questions and answers can help you make a confident, informed decision.

Procedure cost in other countries

Here is an overview of how the estimated cost, hospital stay, and recovery time for stiff man syndrome compare across other countries where we have data.

Country Estimated cost range Typical stay Recovery time View details
India INR 50 Thousand – 300 Thousand 0-3 days (typically outpatient for diagnostics; inpatient may be required for initiating certain immunotherapies) ~ Ongoing management; initial symptom control may take several weeks to months Know More
Turkey TRY 175 Thousand – 1.05 Million 0-3 days (typically outpatient for diagnostics; inpatient may be required for initiating certain immunotherapies) ~ Ongoing management; initial symptom control may take several weeks to months Know More

Top hospitals for Stiff Man Syndrome in India

These partner hospitals in India have dedicated neurology teams and experience managing patients undergoing stiff man syndrome.

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432+ Rating

Manipal Hospital Gurgaon

  • IconGurgaon, India
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2478+ Rating

Manipal Hospital Jayanagar

  • IconBangalore, India
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1610+ Rating

Manipal Hospital Varthur Road

  • IconBangalore, India
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91+ Rating

Manipal Hospital Malleshwaram

  • IconBangalore, India
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6016+ Rating

Manipal Hospital Mysore

  • IconMysore, India
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1837+ Rating

Manipal Hospital Salem

  • IconSalem, India
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847+ Rating

Manipal Hospital Sarjapur Road

  • IconBangalore, India
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180+ Rating

Manipal Hospital Vijayawada

  • Iconvijayawada, India
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2882+ Rating

Manipal Hospital Whitefield

  • IconBangalore, India
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534+ Rating

Manipal Hospital Yeshwanthpur

  • IconBangalore, India
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5990+ Rating

Manipal Hospital Rangapani

  • IconSiliguri, India
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5734+ Rating

Manipal Hospital Siliguri

  • IconSiliguri, India
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279+ Rating

Manipal Hospital Jaipur

  • IconJaipur, India
  • Icon55 Doctors
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98+ Rating

Manipal Hospital Doddaballapur

  • IconBangalore, India
  • Icon30 Doctors
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65+ Rating

Manipal Hospital Salt Lake

  • IconKolkata, India
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135+ Rating

Manipal Hospital Goa

  • IconPanaji, India
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12320+ Rating

Manipal Hospital Kanakapura Road

  • IconBangalore, India
  • Icon78 Doctors
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185+ Rating

Manipal Hospital Ranchi

  • IconRanchi, India
  • Icon41 Doctors
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872+ Rating

Manipal Hospital Millers Road

  • IconBangalore, India
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1161+ Rating

Artemis Hospital Gurgaon

  • IconGurgaon, India
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694+ Rating

Manipal Hospital Kharadi

  • IconPune, India
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156+ Rating

Manipal Hospital Patiala

  • IconPatiala, India
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181+ Rating

KMC Hospital Mangalore

  • IconMangalore, India
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PATIENT REVIEW

Amit Khan, a 42-year-old software engineer...

Amit Khan, a 42-year-old software engineer and father of two, had always been active. Over the past 18 months, he developed a creeping stiffness in his back and legs, which he initially blamed on long hours at his desk. The stiffness evolved into painful, unpredictable muscle spasms so severe they would knock him off his feet. Loud noises or sudden stress, like his children shouting, could trigger an episode. He became afraid to drive or play with his kids, sinking into anxiety and feeling like a prisoner in his own rigid body. After months of misdiagnoses of anxiety or back problems, a neurologist recognized the pattern. She diagnosed Stiff Person Syndrome (SPS) and recommended intravenous immunoglobulin (IVIG) therapy to modulate his overactive immune system. Amit underwent his first 5-day IVIG infusion in the hospital, feeling hopeful but nervous. The process was tiring, but he experienced no major side effects. Within a few weeks, the frequency and intensity of his spasms decreased significantly. The constant background stiffness softened. While not cured, Amit regained the ability to walk confidently, drive short distances, and hug his children without fear of a spasm. Emotionally, he moved from a place of terror and isolation to one of cautious optimism, feeling he had his life and his role as a father back within reach.

Neurologists for Stiff Man Syndrome

Explore experienced neurologists who regularly perform stiff man syndrome and provide pre- and post-operative care in India.

Dr. Bindu Thankappan
  • 18 Years Experience
  • Neurologist
Speaks: English, Tamil, Hindi
Consult Charge ₹ 900
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Miot Hospital Chennai, Chennai

OPD-desk synced • Updated
Dr. AK Roy
  • 46 Years Experience
  • Neurologist
Speaks: English, Hindi
Consult Charge ₹ 1000
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Old Airport Road, Bangalore

OPD-desk synced • Updated
Dr. Uday Murgod
  • 25 Years Experience
  • Neurologist
Speaks: English, Hindi
Consult Charge ₹ 1000
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Old Airport Road, Bangalore

OPD-desk synced • Updated
Dr. Vivek Iyer
  • 13 Years Experience
  • Neurologist
Speaks: English, Hindi, Tamil
Consult Charge ₹ 500

MediFyr Plus SIMS Hospital Vadapalani, Chennai

OPD-desk synced • Updated
Dr. Rithesh R Nair
  • 13 Years Experience
  • Neurologist
Speaks: English, Hindi, Tamil
Consult Charge ₹ 500

MediFyr Plus SIMS Hospital Vadapalani, Chennai

OPD-desk synced • Updated
Dr. Pradyut Ranjan Bhuyan
  • 19 Years Experience
  • Neurologist
Speaks: English, Hindi
Consult Charge ₹ 1000
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Bhubaneswar, Bhubaneshwar

OPD-desk synced • Updated
Dr. Laxmidhar Parhi
  • 26 Years Experience
  • Neurologist
Speaks: English, Hindi
Consult Charge ₹ 1250
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Bhubaneswar, Bhubaneshwar

OPD-desk synced • Updated
Dr. LAKSHMI PRIYA INAPAKOLLA
  • 8 Years Experience
  • Neurologist
Speaks: English, Hindi
Consult Charge ₹ 1000
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Kamineni Hospital, Tadigadapa, vijayawada

OPD-desk synced • Updated
Dr. Aakash Agrawal
  • 9 Years Experience
  • Neurologist
Speaks: English, Hindi
Consult Charge ₹ 1000
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Bhubaneswar, Bhubaneshwar

OPD-desk synced • Updated
Dr. KRISHNAVENI VANAPALA
  • 5 Years Experience
  • Neurologist
Speaks: English, Hindi
Consult Charge ₹ 1000
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Kamineni Hospital, Tadigadapa, vijayawada

OPD-desk synced • Updated
Dr. NAREDDY SANDEEP REDDY
  • 3 Years Experience
  • Neurologist
Speaks: English, Hindi
Consult Charge ₹ 1000
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Kamineni Hospital LB Nagar, Hyderabad

OPD-desk synced • Updated
Dr. KAMLESH M CHAWDA
  • 32 Years Experience
  • Neurologist
Speaks: English, Hindi
Consult Charge ₹ 1000
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Kamineni Hospital LB Nagar, Hyderabad

OPD-desk synced • Updated
Dr. Apurva Nagesh Sharma
  • 11 Years Experience
  • Neurologist
Speaks: English, Hindi
Consult Charge ₹ 1200
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Gurgaon, Gurgaon

OPD-desk synced • Updated
Dr. DR M. LAKSHMI LAVANYA
  • 7 Years Experience
  • Neurologist
Speaks: English, Hindi
Consult Charge ₹ 1000
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Kamineni Hospital LB Nagar, Hyderabad

OPD-desk synced • Updated
Dr. Shishir Pandey
  • 8 Years Experience
  • Neurologist
Speaks: English, Hindi
Consult Charge ₹ 700
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Ghaziabad, Ghaziabad

OPD-desk synced • Updated
Dr. Jay Dip Ray Chaudhuri
  • 32 Years Experience
  • Neurologist
Speaks: English, Hindi
Consult Charge ₹ 900
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Old Airport Road, Bangalore

OPD-desk synced • Updated
Dr. Pramod Krishnan
  • 19 Years Experience
  • Neurologist
Speaks: English, Hindi
Consult Charge ₹ 1000
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Old Airport Road, Bangalore

OPD-desk synced • Updated
Dr. Manjunath Mahadevappa
  • 15 Years Experience
  • Neurologist
Speaks: English, Hindi
Consult Charge ₹ 1000
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Old Airport Road, Bangalore

OPD-desk synced • Updated
Dr. Veena Vedartham
  • 14 Years Experience
  • Neurologist
Speaks: English, Hindi
Consult Charge ₹ 1000
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Old Airport Road, Bangalore

OPD-desk synced • Updated
Dr. Neeraj Kumar
  • 13 Years Experience
  • Neurologist
Speaks: English, Hindi
Consult Charge ₹ 1000
Available Today
December: 08:00 AM - 08:00 PM

Metro Hospital, Sector 11, Noida

OPD-desk synced • Updated