Learn about Thrombolytic Therapy Treatment in India — how it works, who it is for, recovery timelines, and what to expect before and after surgery. Compare hospitals and doctors experienced in Thrombolytic Therapy and request assistance for cost estimates or appointments.

About Thrombolytic Therapy

Thrombolytic therapy, when performed by an ENT (Ear, Nose, and Throat) specialist, is a targeted medical procedure used to dissolve dangerous blood clots that form within the blood vessels of the head and neck region. This treatment is critical for restoring blood flow and preventing severe complications like tissue death (necrosis) or stroke. The ENT specialist administers clot-busting medications, such as tissue plasminogen activator (tPA), directly into the affected vessel or systemically, depending on the clot's location and severity. This procedure is a vital, time-sensitive intervention for conditions like internal jugular vein thrombosis, cavernous sinus thrombosis, or other otolaryngologic vascular emergencies, aiming to quickly resolve the obstruction and preserve vital functions.

Key Highlights

    Rapid dissolution of life-threatening blood clots in the head and neck.Can prevent stroke, tissue necrosis, and permanent neurological damage.Minimally invasive approach when administered via catheter-directed techniques.Time-sensitive treatment that can significantly improve patient outcomes when delivered promptly.Performed by a specialized ENT surgeon with expertise in vascular anatomy of the region.

Who is this surgery for?

  • Internal Jugular Vein Thrombosis (IJVT).
  • Cavernous Sinus Thrombosis.
  • Lateral Sinus Thrombosis secondary to otogenic infection.
  • Selected cases of acute ischemic stroke with a known otolaryngologic source (e.g., from a neck dissection).
  • Severe facial or orbital cellulitis with suspected septic thrombophlebitis.
  • Vascular compromise in free tissue flaps following head and neck reconstructive surgery.

How to prepare

  • Immediate imaging studies (CT angiography, MRV, or Doppler ultrasound) to confirm clot location and extent.
  • Rapid blood tests to assess clotting function, kidney function, and rule out contraindications.
  • Detailed patient history to check for recent surgery, bleeding disorders, or history of hemorrhagic stroke.
  • Informed consent process explaining the urgent nature, benefits, and risks of thrombolysis.
  • Establishment of intravenous (IV) access and continuous vital sign monitoring.

Risks & possible complications

  • Bleeding complications, including intracranial hemorrhage (most serious risk).
  • Bleeding at puncture or surgical sites.
  • Allergic reaction to the thrombolytic agent.
  • Distal embolism (clot fragments traveling to other areas).
  • Re-perfusion injury or edema in the affected tissue.
  • Failure to completely dissolve the clot, requiring additional intervention.

Recovery & hospital stay

  • Close monitoring in an Intensive Care Unit (ICU) or high-dependency unit for at least 24 hours.
  • Frequent neurological checks and monitoring of the puncture/infusion site for bleeding.
  • Bed rest for several hours post-procedure to minimize bleeding risk.
  • Continuation of anticoagulant medications (like heparin) to prevent clot reformation.
  • Follow-up imaging to confirm clot resolution and assess blood flow.
  • Management of the underlying condition that caused the thrombosis (e.g., antibiotics for infection).
  • checked Typical hospital stay: 3-7 days
  • checked Expected recovery time: 2-4 weeks

Frequently Asked Questions

If you are considering thrombolytic therapy in India, these questions and answers can help you make a confident, informed decision.

Procedure cost in other countries

Here is an overview of how the estimated cost, hospital stay, and recovery time for thrombolytic therapy compare across other countries where we have data.

Country Estimated cost range Typical stay Recovery time View details
India INR 80 Thousand – 250 Thousand 3-7 days ~ 2-4 weeks Know More
Turkey TRY 280 Thousand – 875 Thousand 3-7 days ~ 2-4 weeks Know More

Top hospitals for Thrombolytic Therapy in India

These partner hospitals in India have dedicated ent teams and experience managing patients undergoing thrombolytic therapy.

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Manipal Hospital Dwarka

  • IconDelhi, India
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2478+ Rating

Manipal Hospital Jayanagar

  • IconBangalore, India
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91+ Rating

Manipal Hospital Malleshwaram

  • IconBangalore, India
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1837+ Rating

Manipal Hospital Salem

  • IconSalem, India
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5734+ Rating

Manipal Hospital Siliguri

  • IconSiliguri, India
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98+ Rating

Manipal Hospital Doddaballapur

  • IconBangalore, India
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65+ Rating

Manipal Hospital Salt Lake

  • IconKolkata, India
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135+ Rating

Manipal Hospital Goa

  • IconPanaji, India
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12320+ Rating

Manipal Hospital Kanakapura Road

  • IconBangalore, India
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185+ Rating

Manipal Hospital Ranchi

  • IconRanchi, India
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872+ Rating

Manipal Hospital Millers Road

  • IconBangalore, India
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418+ Rating

Manipal Hospital Hebbal

  • IconBangalore, India
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418+ Rating

Manipal Hospital Hebbal

  • IconBangalore, India
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156+ Rating

Manipal Hospital Patiala

  • IconPatiala, India
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181+ Rating

KMC Hospital Mangalore

  • IconMangalore, India
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PATIENT REVIEW

Sophia Kumar, a 42-year-old graphic designer...

Sophia Kumar, a 42-year-old graphic designer and mother of two, had always been healthy. Her life changed suddenly when she woke up with profound hearing loss and a roaring tinnitus in her right ear. Over the next 12 hours, she developed severe vertigo, making it impossible to stand without vomiting. A frantic trip to the ER and an urgent MRI revealed an acute occlusion of the right internal auditory artery, a stroke affecting her inner ear. The ENT specialist explained that time was critical; the sensory cells were dying. He recommended immediate intra-arterial thrombolytic therapy, a targeted clot-busting treatment delivered via a catheter to try and restore blood flow to her cochlea and vestibular system. Terrified of permanent deafness and imbalance, Sophia consented. The procedure was intense; she was awake but sedated, feeling pressure as the interventional radiologist navigated the micro-catheter. Within hours, the roaring in her ear began to fade. Over the next two days in the stroke unit, her vertigo subsided dramatically. While she was left with a moderate high-frequency hearing loss and mild tinnitus, her functional hearing and balance recovered enough to return to work and family life. Her emotional journey was a rollercoaster, from the sheer panic of sudden sensory loss, through the anxiety of an urgent brain procedure, to immense gratitude for the partial recovery that allowed her to hear her children's voices again.

ENT Specialists for Thrombolytic Therapy

Explore experienced ent specialists who regularly perform thrombolytic therapy and provide pre- and post-operative care in India.

Dr. Muthu kumar s
  • 16 Years Experience
  • ENT Specialist
Speaks: English, Tamil, Hindi
Consult Charge ₹ 900
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Miot Hospital Chennai, Chennai

OPD-desk synced • Updated
Dr. Gayatri Pandit
  • 21 Years Experience
  • ENT Specialist
Speaks: English, Hindi
Consult Charge ₹ 700
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Yeshwanthpur, Bangalore

OPD-desk synced • Updated
Dr. Diptarka Bhattacharyya
  • 14 Years Experience
  • ENT Specialist
Speaks: English, Hindi
Consult Charge ₹ 800
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Sarjapur Road, Bangalore

OPD-desk synced • Updated
Dr. J Jayabaskar
  • 9 Years Experience
  • ENT Specialist
Speaks: English, Hindi
Consult Charge ₹ 500
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Salem, Salem

OPD-desk synced • Updated
Dr. Shalina Ray
  • 26 Years Experience
  • ENT Specialist
Speaks: English, Hindi
Consult Charge ₹ 450
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Whitefield, Bangalore

OPD-desk synced • Updated
Dr. Anitha Kumari AM
  • 24 Years Experience
  • ENT Specialist
Speaks: English, Hindi
Consult Charge ₹ 500
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Whitefield, Bangalore

OPD-desk synced • Updated
Dr. Vijay Rangachari
  • 21 Years Experience
  • ENT Specialist
Speaks: English, Hindi
Consult Charge ₹ 500
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Whitefield, Bangalore

OPD-desk synced • Updated
Dr. Alok Banka
  • 18 Years Experience
  • ENT Specialist
Speaks: English, Hindi
Consult Charge ₹ 800
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Whitefield, Bangalore

OPD-desk synced • Updated
Dr. EV Raman
  • 43 Years Experience
  • ENT Specialist
Speaks: English, Hindi
Consult Charge ₹ 850
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Old Airport Road, Bangalore

OPD-desk synced • Updated
Dr. Girish Rai
  • 38 Years Experience
  • ENT Specialist
Speaks: English, Hindi
Consult Charge ₹ 850
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Old Airport Road, Bangalore

OPD-desk synced • Updated
Dr. Bathi Reddy
  • 36 Years Experience
  • ENT Specialist
Speaks: English, Hindi
Consult Charge ₹ 850
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Old Airport Road, Bangalore

OPD-desk synced • Updated
Dr. Anitha Kumari AM
  • 24 Years Experience
  • ENT Specialist
Speaks: English, Hindi
Consult Charge ₹ 850
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Old Airport Road, Bangalore

OPD-desk synced • Updated
Dr. Satish Nair
  • 29 Years Experience
  • ENT Specialist
Speaks: English, Hindi
Consult Charge ₹ 900
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Old Airport Road, Bangalore

OPD-desk synced • Updated
Dr. Parvinderjit Singh Kohli
  • 20 Years Experience
  • ENT Specialist
Speaks: English, Hindi
Consult Charge ₹ 900
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Patiala, Patiala

OPD-desk synced • Updated
Dr. Vishal Sharma
  • 10 Years Experience
  • ENT Specialist
Speaks: English, Hindi
Consult Charge ₹ 450
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Patiala, Patiala

OPD-desk synced • Updated
Dr. Praveen Kumar R
  • 14 Years Experience
  • ENT Specialist
Speaks: English, Hindi
Consult Charge ₹ 800
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Mysore, Mysore

OPD-desk synced • Updated
Dr. Dathathri HA
  • 14 Years Experience
  • ENT Specialist
Speaks: English, Hindi
Consult Charge ₹ 800
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Mysore, Mysore

OPD-desk synced • Updated
Dr. Arun Raykar N Raykar
  • 19 Years Experience
  • ENT Specialist
Speaks: English, Hindi
Consult Charge ₹ 1000
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Malleshwaram, Bangalore

OPD-desk synced • Updated
Dr. Shalini Bansal
  • 8 Years Experience
  • ENT Specialist
Speaks: English, Hindi
Consult Charge ₹ 550
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Kharadi, Pune

OPD-desk synced • Updated
Dr. Shanthala MN
  • 26 Years Experience
  • ENT Specialist
Speaks: English, Hindi
Consult Charge ₹ 800
Available Today
December: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Jayanagar, Bangalore

OPD-desk synced • Updated