About Thrombolytic Therapy
Key Highlights
-
Rapid dissolution of life-threatening blood clots in the head and neck.Can prevent stroke, tissue necrosis, and permanent neurological damage.Minimally invasive approach when administered via catheter-directed techniques.Time-sensitive treatment that can significantly improve patient outcomes when delivered promptly.Performed by a specialized ENT surgeon with expertise in vascular anatomy of the region.
Who is this surgery for?
- Internal Jugular Vein Thrombosis (IJVT).
- Cavernous Sinus Thrombosis.
- Lateral Sinus Thrombosis secondary to otogenic infection.
- Selected cases of acute ischemic stroke with a known otolaryngologic source (e.g., from a neck dissection).
- Severe facial or orbital cellulitis with suspected septic thrombophlebitis.
- Vascular compromise in free tissue flaps following head and neck reconstructive surgery.
How to prepare
- Immediate imaging studies (CT angiography, MRV, or Doppler ultrasound) to confirm clot location and extent.
- Rapid blood tests to assess clotting function, kidney function, and rule out contraindications.
- Detailed patient history to check for recent surgery, bleeding disorders, or history of hemorrhagic stroke.
- Informed consent process explaining the urgent nature, benefits, and risks of thrombolysis.
- Establishment of intravenous (IV) access and continuous vital sign monitoring.
Risks & possible complications
- Bleeding complications, including intracranial hemorrhage (most serious risk).
- Bleeding at puncture or surgical sites.
- Allergic reaction to the thrombolytic agent.
- Distal embolism (clot fragments traveling to other areas).
- Re-perfusion injury or edema in the affected tissue.
- Failure to completely dissolve the clot, requiring additional intervention.
Recovery & hospital stay
- Close monitoring in an Intensive Care Unit (ICU) or high-dependency unit for at least 24 hours.
- Frequent neurological checks and monitoring of the puncture/infusion site for bleeding.
- Bed rest for several hours post-procedure to minimize bleeding risk.
- Continuation of anticoagulant medications (like heparin) to prevent clot reformation.
- Follow-up imaging to confirm clot resolution and assess blood flow.
- Management of the underlying condition that caused the thrombosis (e.g., antibiotics for infection).
-
Typical hospital stay: 3-7 days
-
Expected recovery time: 2-4 weeks
Frequently Asked Questions
If you are considering thrombolytic therapy in India, these questions and answers can help you make a confident, informed decision.
Popular choices for thrombolytic therapy in India include Manipal Hospital Dwarka, Manipal Hospital Jayanagar, Manipal Hospital Malleshwaram, Manipal Hospital Hebbal, Manipal Hospital Hebbal, KMC Hospital Mangalore, known for experienced specialists and advanced surgical infrastructure.
Look at the doctor’s years of experience, hospital association, patient reviews, and how often they perform thrombolytic therapy. MediFyr helps you compare ent specialists and book consultations online.
The overall cost depends on hospital category, surgeon’s experience, room type, implant or device used (if any), length of stay, tests, and post-operative care. Our team can help you get cost estimates from multiple hospitals before you decide.
Procedure cost in other countries
Here is an overview of how the estimated cost, hospital stay, and recovery time for thrombolytic therapy compare across other countries where we have data.
Top hospitals for Thrombolytic Therapy in India
These partner hospitals in India have dedicated ent teams and experience managing patients undergoing thrombolytic therapy.
Sophia Kumar, a 42-year-old graphic designer...
Sophia Kumar, a 42-year-old graphic designer and mother of two, had always been healthy. Her life changed suddenly when she woke up with profound hearing loss and a roaring tinnitus in her right ear. Over the next 12 hours, she developed severe vertigo, making it impossible to stand without vomiting. A frantic trip to the ER and an urgent MRI revealed an acute occlusion of the right internal auditory artery, a stroke affecting her inner ear. The ENT specialist explained that time was critical; the sensory cells were dying. He recommended immediate intra-arterial thrombolytic therapy, a targeted clot-busting treatment delivered via a catheter to try and restore blood flow to her cochlea and vestibular system. Terrified of permanent deafness and imbalance, Sophia consented. The procedure was intense; she was awake but sedated, feeling pressure as the interventional radiologist navigated the micro-catheter. Within hours, the roaring in her ear began to fade. Over the next two days in the stroke unit, her vertigo subsided dramatically. While she was left with a moderate high-frequency hearing loss and mild tinnitus, her functional hearing and balance recovered enough to return to work and family life. Her emotional journey was a rollercoaster, from the sheer panic of sudden sensory loss, through the anxiety of an urgent brain procedure, to immense gratitude for the partial recovery that allowed her to hear her children's voices again.
ENT Specialists for Thrombolytic Therapy
Explore experienced ent specialists who regularly perform thrombolytic therapy and provide pre- and post-operative care in India.
- 16 Years Experience
- ENT Specialist
Miot Hospital Chennai, Chennai
- 21 Years Experience
- ENT Specialist
Manipal Hospital Yeshwanthpur, Bangalore
- 14 Years Experience
- ENT Specialist
Manipal Hospital Sarjapur Road, Bangalore
- 9 Years Experience
- ENT Specialist
- 26 Years Experience
- ENT Specialist
Manipal Hospital Whitefield, Bangalore
- 24 Years Experience
- ENT Specialist
Manipal Hospital Whitefield, Bangalore
- 21 Years Experience
- ENT Specialist
Manipal Hospital Whitefield, Bangalore
- 18 Years Experience
- ENT Specialist
Manipal Hospital Whitefield, Bangalore
- 43 Years Experience
- ENT Specialist
Manipal Hospital Old Airport Road, Bangalore
- 38 Years Experience
- ENT Specialist
Manipal Hospital Old Airport Road, Bangalore
- 36 Years Experience
- ENT Specialist
Manipal Hospital Old Airport Road, Bangalore
- 24 Years Experience
- ENT Specialist
Manipal Hospital Old Airport Road, Bangalore
- 29 Years Experience
- ENT Specialist
Manipal Hospital Old Airport Road, Bangalore
- 20 Years Experience
- ENT Specialist
Manipal Hospital Patiala, Patiala
- 10 Years Experience
- ENT Specialist
Manipal Hospital Patiala, Patiala
- 14 Years Experience
- ENT Specialist
Manipal Hospital Mysore, Mysore
- 14 Years Experience
- ENT Specialist
Manipal Hospital Mysore, Mysore
- 19 Years Experience
- ENT Specialist
Manipal Hospital Malleshwaram, Bangalore
- 8 Years Experience
- ENT Specialist
Manipal Hospital Kharadi, Pune
- 26 Years Experience
- ENT Specialist
Manipal Hospital Jayanagar, Bangalore