About Wilsons Disease
Key Highlights
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Provides a definitive diagnosis through genetic analysis of the ATP7B gene.Enables personalized, lifelong treatment plans to manage copper accumulation.Offers crucial genetic counseling for patients and their families regarding inheritance risks.Focuses on preventing severe and irreversible liver, brain, and kidney damage.Involves a multidisciplinary team for comprehensive care of neurological and hepatic symptoms.
Who is this surgery for?
- Unexplained liver disease (hepatitis, cirrhosis, acute liver failure) in a child, adolescent, or young adult.
- Neurological symptoms without clear cause, such as tremor, dystonia, slurred speech, or personality changes.
- Kayser-Fleischer rings (copper deposits in the cornea) observed during an eye examination.
- Family history of Wilson's Disease or unexplained liver or neurological illness in siblings.
- Low blood ceruloplasmin level and/or elevated 24-hour urinary copper excretion.
How to prepare
- Detailed clinical evaluation including history of liver, neurological, or psychiatric symptoms.
- Blood tests to measure ceruloplasmin, serum copper, and liver function.
- 24-hour urine collection to quantify copper excretion.
- Slit-lamp eye examination by an ophthalmologist to check for Kayser-Fleischer rings.
- Genetic counseling session to discuss the implications of testing for the patient and family.
- Informed consent process explaining the purpose, benefits, and limitations of genetic testing.
Risks & possible complications
- Neurological worsening can sometimes occur initially after starting chelation therapy.
- Side effects of medications, including nausea, bone marrow suppression, or kidney issues.
- Risk of non-adherence to lifelong treatment, leading to disease progression and organ failure.
- Psychological impact of a lifelong diagnosis and the need for constant monitoring.
- Potential for diagnostic uncertainty if genetic variants of unknown significance are found.
Recovery & hospital stay
- Treatment is lifelong; 'recovery' refers to achieving and maintaining clinical stability.
- Regular monitoring of liver enzymes, blood counts, and urinary copper is mandatory.
- Strict adherence to prescribed medications (chelators or zinc) and a low-copper diet.
- Ongoing neurological and psychiatric assessments to manage symptoms.
- Periodic follow-ups with the genetic medicine specialist, hepatologist, and neurologist.
- Genetic counseling for family members regarding carrier testing and reproductive options.
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Typical hospital stay: 0-3 days (for initial diagnostic workup or management of acute complications)
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Expected recovery time: Lifelong management (Clinical improvement may be seen over months to years with treatment)
Frequently Asked Questions
If you are considering wilsons disease in India, these questions and answers can help you make a confident, informed decision.
Top-rated hospitals in India with genetic medicine departments and experienced surgeons are ideal for this procedure. Use MediFyr to compare facilities, reviews, and doctor profiles before you decide.
Look at the doctor’s years of experience, hospital association, patient reviews, and how often they perform wilsons disease. MediFyr helps you compare genetic medicines and book consultations online.
The overall cost depends on hospital category, surgeon’s experience, room type, implant or device used (if any), length of stay, tests, and post-operative care. Our team can help you get cost estimates from multiple hospitals before you decide.
Procedure cost in other countries
Here is an overview of how the estimated cost, hospital stay, and recovery time for wilsons disease compare across other countries where we have data.
| Country | Estimated cost range | Typical stay | Recovery time | View details |
|---|---|---|---|---|
| India | INR 50 Thousand – 200 Thousand | 0-3 days (for initial diagnostic workup or management of acute complications) | ~ Lifelong management (Clinical improvement may be seen over months to years with treatment) | Know More |
| Turkey | TRY 175 Thousand – 700 Thousand | 0-3 days (for initial diagnostic workup or management of acute complications) | ~ Lifelong management (Clinical improvement may be seen over months to years with treatment) | Know More |
Neha Reddy, a 28-year-old software engineer...
Neha Reddy, a 28-year-old software engineer from Hyderabad, had always been an overachiever. Recently, she began experiencing unexplained fatigue, hand tremors that made coding difficult, and occasional abdominal pain. Her primary care physician noticed a slight golden-brown ring around her corneas during a routine check-up and referred her to a genetic medicine specialist. The specialist, suspecting Wilson's Disease, recommended genetic testing to confirm mutations in the ATP7B gene. The testing involved a simple blood draw, which was sent for analysis. The results confirmed the diagnosis, showing she had inherited two faulty copies of the gene. Post-diagnosis, Neha started on chelation therapy (D-penicillamine) and a strict low-copper diet. Within months, her tremors subsided and her energy returned. Emotionally, she moved from fear and confusion about her declining abilities to profound relief. The diagnosis gave her a clear path forward, replacing anxiety with a sense of control over her health and future.
Genetic Medicines for Wilsons Disease
Explore experienced genetic medicines who regularly perform wilsons disease and provide pre- and post-operative care in India.
- 16 Years Experience
- Genetic Medicine
Miot Hospital Chennai, Chennai
- 14 Years Experience
- Genetic Medicine
Miot Hospital Chennai, Chennai
- 4 Years Experience
- Genetic Medicine
Miot Hospital Chennai, Chennai