Prof. M.D. Gürhan Şişman

A 28-year-old professional e-sports athlete presented with debilitating abdominal pain during tournaments. Dr. Şişman discovered a rare case of mesenteric panniculitis triggered by extreme stress and prolonged sitting. Treatment involved a combination of anti-inflammatory medication, a tailored physiotherapy regimen for core stability, and cognitive behavioral therapy for performance anxiety. The patient returned to competition after 8 weeks with a new understanding of mind-gut connection in high-pressure environments.

A 72-year-old retired ship captain from the Black Sea region arrived with unexplained weight loss and jaundice. His complex history included exposure to industrial solvents decades earlier. Dr. Şişman's investigation revealed primary sclerosing cholangitis with an unusual presentation. Instead of standard treatment, he coordinated with occupational medicine specialists to develop a personalized protocol that accounted for the historical toxin exposure. The patient stabilized after 6 months with improved liver function tests.

A 19-year-old university exchange student from Kazakhstan developed severe dysphagia after arriving in Istanbul. She had been secretly practicing extreme breath-holding techniques for free-diving. Dr. Şişman diagnosed a rare form of esophageal spasm triggered by hypoxia. Treatment involved biofeedback therapy and collaboration with a respiratory physiologist to modify her training. She returned to controlled diving after 4 months with monitoring protocols.

A 45-year-old master calligrapher presented with hand tremors affecting his work, which he attributed to a digestive issue. Dr. Şişman identified hepatic encephalopathy from previously undiagnosed NASH cirrhosis, likely exacerbated by years of ingesting small amounts of traditional ink pigments containing heavy metals. A multidisciplinary approach included chelation therapy, dietary modification, and collaboration with occupational therapists to adapt his art practice during recovery.