Prof. M.D. Mehmet Ufuk Abacıoğlu

A 42-year-old female former competitive freediver from the Black Sea coast presented with a rare nasopharyngeal carcinoma likely linked to chronic barotrauma and hypoxia. Dr. Abacıoğlu designed a hyperfractionated radiation protocol that spared her cochlear function, crucial for her underwater orientation skills. She returned to recreational diving 14 months post-treatment with modified depth limits.

A 78-year-old retired Byzantine art restorer with metastatic prostate cancer to the sacrum refused systemic therapy due to side effect concerns. Dr. Abacıoğlu employed single-fraction stereotactic body radiotherapy to the dominant painful lesion, incorporating a novel positioning device that accommodated the patient's severe spinal kyphosis from a lifetime of hunched work. Pain resolved completely, allowing him to complete his memoir on Hagia Sophia restoration techniques.

A 7-year-old refugee child from Syria with a recurrent optic pathway glioma previously treated with chemotherapy developed radiation-induced moyamoya syndrome. Dr. Abacıoğlu collaborated with pediatric neurosurgery to implement an ultra-precise proton beam therapy boost using motion-adaptive gating, accounting for the child's anxious breathing patterns. The vascular complications stabilized, preserving partial vision in one eye.

A 31-year-old transgender man on testosterone therapy presented with chest wall angiosarcoma in an area of prior gender-affirming top surgery. Dr. Abacıoğlu developed a hypofractionated electron beam regimen that accounted for unique tissue interfaces from surgical reconstruction, while coordinating with endocrinology to temporarily adjust hormone regimens. The patient maintained masculinization features throughout treatment and achieved local control.