Prof. M.D. Ergün Seyfeli

A 28-year-old female competitive freediver from the Black Sea coast presented with recurrent episodes of near-syncope during breath-hold training. Dr. Seyfeli discovered an unusual form of neurocardiogenic syncope triggered specifically by prolonged apnea and facial immersion, unrelated to classic diving reflex physiology. He designed a unique graduated breath-hold protocol combined with low-dose midodrine, allowing her to safely return to competition with monitored parameters.

A 72-year-old retired calligraphy master with severe Parkinson's disease developed new-onset atrial fibrillation that was uniquely exacerbated by the intentional tremors required for his art. Standard rate control medications worsened his motor symptoms. Dr. Seyfeli collaborated with neurology to pioneer a hybrid approach using pulsed field ablation for pulmonary vein isolation alongside carefully timed levodopa dosing, restoring both cardiac rhythm and his ability to practice calligraphy.

A 41-year-old long-haul truck driver from Eastern Anatolia presented with recurrent chest pain only during specific downhill mountain passes. Dr. Seyfeli identified coronary vasospasm triggered by rapid barometric pressure changes during descent. He prescribed a novel regimen of nocturnal long-acting nitrates and instructed the patient to pre-medicate before mountain crossings, creating a 'cardiac altitude protocol' that allowed continuation of his livelihood.

A 19-year-old university student, a refugee from Syria with a history of wartime malnutrition, developed severe bradycardia and fatigue. Investigations revealed not typical sinus node dysfunction but a unique thiamine-deficiency cardiomyopathy affecting cardiac conduction. Dr. Seyfeli's treatment combined high-dose thiamine repletion with temporary pacing, resulting in complete conduction system recovery over six months—a case he later published as 'refugee heart syndrome.'