About Lymphocytic Vasculitis
Key Highlights
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Offers a potential cure for severe, refractory lymphocytic vasculitis by resetting the immune system.Can halt progressive organ damage caused by widespread vascular inflammation.Utilizes the patient's own cells (autologous) or a donor's cells (allogeneic) to rebuild healthy bone marrow.Performed in specialized transplant centers with multidisciplinary expertise.Aims for long-term remission and improved quality of life when conventional therapies fail.
Who is this surgery for?
- Severe, life-threatening lymphocytic vasculitis unresponsive to high-dose corticosteroids and immunosuppressants.
- Vasculitis causing critical organ dysfunction (e.g., kidney failure, severe neuropathy, intestinal ischemia).
- Cases where the vasculitis is a manifestation of an underlying hematologic disorder treatable by BMT.
- Rapidly progressive disease where standard treatment poses unacceptable risks or has failed.
- As part of a treatment plan for an underlying condition (e.g., certain leukemias, lymphomas) that also involves vasculitis.
How to prepare
- Comprehensive evaluation including cardiac, pulmonary, renal, and dental assessments.
- Extensive blood tests, imaging scans, and a bone marrow biopsy.
- For allogeneic transplant: a rigorous search and matching process for a suitable donor (related or unrelated).
- For autologous transplant: harvesting and cryopreservation of the patient's own stem cells.
- Pre-transplant conditioning with high-dose chemotherapy and/or radiation therapy to destroy diseased marrow.
- Central venous catheter placement for stem cell infusion and medication administration.
- Psychological counseling and detailed patient/family education about the procedure and recovery.
Risks & possible complications
- Graft-versus-host disease (GVHD) in allogeneic transplants, where donor cells attack the patient's body.
- Graft failure, where the new stem cells do not engraft and produce blood cells.
- Severe infections due to prolonged immune suppression and neutropenia.
- Organ toxicity from conditioning regimens (e.g., to heart, lungs, liver).
- Bleeding and anemia requiring frequent transfusions.
- Long-term risks include secondary cancers, infertility, and chronic GVHD.
- Risk of the original vasculitis or autoimmune condition recurring.
Recovery & hospital stay
- Initial hospital stay of several weeks in a protective isolation room to prevent infection.
- Close monitoring of blood counts, organ function, and signs of engraftment or GVHD.
- Supportive care with antibiotics, antifungals, antivirals, blood product transfusions, and nutritional support.
- Gradual immune system recovery over 6-12 months; revaccination is required.
- Lifelong follow-up with the transplant team to manage late effects and monitor for relapse.
- Strict infection prevention measures, a neutropenic diet, and avoiding crowds initially.
- Rehabilitation, including physical therapy, to regain strength and manage fatigue.
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Typical hospital stay: 4-6 weeks
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Expected recovery time: 6-12 months for full immune recovery
Frequently Asked Questions
If you are considering lymphocytic vasculitis in Turkey, these questions and answers can help you make a confident, informed decision.
Popular choices for lymphocytic vasculitis in Turkey include Liv Hospital Ankara, Istinye Üniversitesi Hastanesi Liv, VM Medical Park Pendik Hastanesi, Medical Park Florya, Medical Park Bahçelievler, known for experienced specialists and advanced surgical infrastructure.
Look at the doctor’s years of experience, hospital association, patient reviews, and how often they perform lymphocytic vasculitis. MediFyr helps you compare bone marrow transplant specialists and book consultations online.
The overall cost depends on hospital category, surgeon’s experience, room type, implant or device used (if any), length of stay, tests, and post-operative care. Our team can help you get cost estimates from multiple hospitals before you decide.
Procedure cost in other countries
Here is an overview of how the estimated cost, hospital stay, and recovery time for lymphocytic vasculitis compare across other countries where we have data.
Top hospitals for Lymphocytic Vasculitis in Turkey
These partner hospitals in Turkey have dedicated bone marrow transplantation teams and experience managing patients undergoing lymphocytic vasculitis.
Sophia Shah, a 45-year-old school teacher...
Sophia Shah, a 45-year-old school teacher and mother of two from Ahmedabad, had a five-year battle with Lymphocytic Vasculitis primarily affecting her skin and nerves. She lived with a painful, burning rash and numbness in her hands and feet, which made teaching and daily chores immensely difficult. Multiple lines of treatment, including rituximab, provided only temporary relief before the symptoms roared back. Her doctors presented allogeneic bone marrow transplantation as a potential curative option. A donor match was found in her brother. The concept of using her brother's immune system to replace her faulty one was daunting but offered hope for a permanent solution. The transplant process was a rollercoaster, graft-versus-host disease (GVHD) caused new complications, including a skin rash and mouth sores, which were frightening. Managing these side effects was challenging. A year post-transplant, her original vasculitis symptoms are in complete remission, and her GVHD is well-controlled with low-dose medication. She has regained sensation in her hands and can hold a pen comfortably again. Emotionally, her journey was defined by a mother's guilt for being unable to care for her family, transformed into profound gratitude for her brother's gift and a renewed sense of strength. She now advocates for donor awareness.