About Cytogenetics
Key Highlights
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Provides a definitive diagnosis for a wide range of genetic and chromosomal disorders.Essential for accurate prognosis and guiding personalized treatment plans, especially in oncology.Critical for prenatal diagnosis and family planning, helping assess risks for future pregnancies.Utilizes advanced techniques like FISH and CMA for high-resolution analysis of chromosomal changes.Often requires only a simple blood draw or tissue sample, making it minimally invasive for most patients.
Who is this surgery for?
- Evaluation of congenital anomalies, developmental delays, or intellectual disabilities in children.
- Diagnosis and monitoring of hematologic malignancies (e.g., leukemia, lymphoma, myeloma).
- Assessment of recurrent pregnancy loss or infertility in couples.
- Prenatal testing following abnormal ultrasound findings or maternal serum screening.
- Diagnosis of suspected genetic syndromes (e.g., Down syndrome, Turner syndrome).
- Evaluation of ambiguous genitalia or disorders of sexual development.
How to prepare
- For a blood sample: Typically no special preparation like fasting is required.
- For prenatal testing (amniocentesis/chorionic villus sampling): A detailed counseling session to discuss risks and benefits is mandatory.
- For bone marrow aspiration: The patient may need to fast and will receive local anesthesia or sedation.
- Patients should inform the geneticist about all current medications and supplements.
- Providing a detailed personal and family medical history is crucial for accurate interpretation.
Risks & possible complications
- For blood draws: Minimal risks include slight pain, bruising, or very rarely, infection at the puncture site.
- For prenatal procedures (amniocentesis/CVS): Small risk of miscarriage, infection, or amniotic fluid leakage.
- For bone marrow biopsy: Risks include pain, bleeding, bruising, or infection at the biopsy site.
- Potential for ambiguous or uncertain results requiring further testing.
- Psychological impact of receiving a diagnosis of a genetic condition.
Recovery & hospital stay
- For standard blood tests: No recovery time is needed; normal activities can be resumed immediately.
- After bone marrow biopsy: Rest is advised for 24-48 hours; the site may be sore for a few days.
- After prenatal procedures: Rest for 24 hours is typically recommended, with monitoring for signs of infection or cramping.
- Results are not immediate; it can take 1-4 weeks for the cell culture and analysis to be completed.
- A follow-up consultation with a genetic counselor or geneticist is essential to discuss the results, their implications, and next steps.
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Typical hospital stay: 0 days (outpatient) or 1 day (if combined with a procedure like bone marrow biopsy)
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Expected recovery time: 0-2 days
Frequently Asked Questions
If you are considering cytogenetics in India, these questions and answers can help you make a confident, informed decision.
Top-rated hospitals in India with genetic medicine departments and experienced surgeons are ideal for this procedure. Use MediFyr to compare facilities, reviews, and doctor profiles before you decide.
Look at the doctor’s years of experience, hospital association, patient reviews, and how often they perform cytogenetics. MediFyr helps you compare genetic medicines and book consultations online.
The overall cost depends on hospital category, surgeon’s experience, room type, implant or device used (if any), length of stay, tests, and post-operative care. Our team can help you get cost estimates from multiple hospitals before you decide.
Procedure cost in other countries
Here is an overview of how the estimated cost, hospital stay, and recovery time for cytogenetics compare across other countries where we have data.
| Country | Estimated cost range | Typical stay | Recovery time | View details |
|---|---|---|---|---|
| India | INR 5 Thousand – 25 Thousand | 0 days (outpatient) or 1 day (if combined with a procedure like bone marrow biopsy) | ~ 0-2 days | Know More |
| Turkey | TRY 17.5 Thousand – 87.5 Thousand | 0 days (outpatient) or 1 day (if combined with a procedure like bone marrow biopsy) | ~ 0-2 days | Know More |
Anjali Johnson, a 28-year-old teacher, was...
Anjali Johnson, a 28-year-old teacher, was diagnosed with Acute Myeloid Leukemia (AML). As part of her initial workup, her oncologist ordered cytogenetic testing on her bone marrow sample to analyze the chromosomes of her leukemia cells. This was crucial for determining the aggressiveness of her cancer and guiding treatment. The procedure was performed during her initial bone marrow biopsy, which was uncomfortable but manageable. The cytogenetics report revealed a specific chromosomal translocation, t(8;21), which classified her AML into a favorable risk category. This meant she had a significantly higher chance of achieving remission with standard chemotherapy and potentially avoiding a stem cell transplant initially. The emotional journey was a rollercoaster: the shock of the cancer diagnosis was followed by the anxiety of waiting for these definitive results. The favorable cytogenetic finding became a beacon of hope, providing concrete, optimistic data to hold onto during the difficult months of treatment ahead.
Genetic Medicines for Cytogenetics
Explore experienced genetic medicines who regularly perform cytogenetics and provide pre- and post-operative care in India.
- 16 Years Experience
- Genetic Medicine
Miot Hospital Chennai, Chennai
- 14 Years Experience
- Genetic Medicine
Miot Hospital Chennai, Chennai
- 4 Years Experience
- Genetic Medicine
Miot Hospital Chennai, Chennai