About KRAS Mutation Analysis
Key Highlights
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Guides personalized, targeted cancer therapy decisions.Helps predict response to specific drugs like EGFR inhibitors.Provides critical prognostic information for several cancer types.Uses advanced molecular techniques for high accuracy.Enables a precision medicine approach to oncology care.
Who is this surgery for?
- Diagnosis of metastatic colorectal cancer to guide anti-EGFR therapy.
- Evaluation of advanced non-small cell lung cancer (NSCLC).
- Diagnosis and management of pancreatic ductal adenocarcinoma.
- Part of the molecular profiling for various solid tumors.
- When standard chemotherapy has failed, to identify targeted options.
- For patients being considered for clinical trials involving KRAS-targeted drugs.
How to prepare
- Consultation with an oncologist or genetic counselor to discuss the test's purpose.
- Provision of a formalin-fixed, paraffin-embedded (FFPE) tissue block or slides from a prior biopsy or surgery.
- If a new biopsy is needed, standard pre-biopsy preparations (like fasting) may apply.
- Informed consent process explaining the genetic nature of the test.
- Insurance pre-authorization may be required.
Risks & possible complications
- Risks are primarily associated with the tissue biopsy procedure (if a new sample is needed), such as bleeding, infection, or pain.
- Potential for an inconclusive result if the tissue sample has insufficient tumor DNA.
- Psychological impact of genetic information related to prognosis.
- Possible insurance or privacy concerns regarding genetic data (handled under strict confidentiality).
- No direct physical risks from the laboratory analysis itself.
Recovery & hospital stay
- Recovery is from the biopsy procedure, not the genetic test. Patients can typically resume normal activities shortly after a needle biopsy.
- Care for the biopsy site as instructed (e.g., keeping it clean and dry).
- Results are usually available within 7-14 business days and will be discussed in a follow-up appointment with the oncologist.
- The oncologist will explain the results and their implications for the treatment plan.
- No specific lifestyle changes are required post-analysis.
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Typical hospital stay: 0 days (outpatient for biopsy if needed)
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Expected recovery time: 0-2 days (from biopsy procedure)
Frequently Asked Questions
If you are considering kras mutation analysis in India, these questions and answers can help you make a confident, informed decision.
Top-rated hospitals in India with genetic medicine departments and experienced surgeons are ideal for this procedure. Use MediFyr to compare facilities, reviews, and doctor profiles before you decide.
Look at the doctor’s years of experience, hospital association, patient reviews, and how often they perform kras mutation analysis. MediFyr helps you compare genetic medicines and book consultations online.
The overall cost depends on hospital category, surgeon’s experience, room type, implant or device used (if any), length of stay, tests, and post-operative care. Our team can help you get cost estimates from multiple hospitals before you decide.
Procedure cost in other countries
Here is an overview of how the estimated cost, hospital stay, and recovery time for kras mutation analysis compare across other countries where we have data.
| Country | Estimated cost range | Typical stay | Recovery time | View details |
|---|---|---|---|---|
| India | INR 8 Thousand – 25 Thousand | 0 days (outpatient for biopsy if needed) | ~ 0-2 days (from biopsy procedure) | Know More |
| Turkey | TRY 28 Thousand – 87.5 Thousand | 0 days (outpatient for biopsy if needed) | ~ 0-2 days (from biopsy procedure) | Know More |
Angel Singh, a 58-year-old former school...
Angel Singh, a 58-year-old former school librarian, had always been health-conscious. Her world tilted when she developed a persistent cough and unexplained weight loss. A CT scan revealed a mass in her lung. After a biopsy confirmed stage IV non-small cell lung cancer (NSCLC), her oncologist, Dr. Mehta, recommended a KRAS mutation analysis. 'This test,' she explained, 'can tell us the specific 'driver' of your cancer and open doors to newer, targeted therapies.' The procedure itself was straightforward, a small piece of her biopsy tissue was sent to a specialized lab. The wait for results was agonizing; Angel felt like a statistic, her future hinging on a microscopic genetic typo. When the results came back positive for a KRAS G12C mutation, it was a bittersweet moment. It confirmed the aggressiveness of her disease, but it also made her eligible for a newly approved targeted drug called sotorasib. Starting the treatment, she experienced manageable side effects like fatigue. Six months later, follow-up scans showed significant tumor shrinkage. Emotionally, Angel moved from feeling like a passive victim of a random illness to an active participant in a targeted fight. The mutation analysis gave her cancer a name and, crucially, a specific adversary to tackle, replacing overwhelming fear with focused hope.
Genetic Medicines for KRAS Mutation Analysis
Explore experienced genetic medicines who regularly perform kras mutation analysis and provide pre- and post-operative care in India.
- 16 Years Experience
- Genetic Medicine
Miot Hospital Chennai, Chennai
- 14 Years Experience
- Genetic Medicine
Miot Hospital Chennai, Chennai
- 4 Years Experience
- Genetic Medicine
Miot Hospital Chennai, Chennai