About KRAS Mutation Analysis
Key Highlights
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Guides personalized, targeted cancer therapy decisions.Helps predict response to specific drugs like EGFR inhibitors.Provides critical prognostic information for several cancer types.Uses advanced molecular techniques for high accuracy.Enables a precision medicine approach to oncology care.
Who is this surgery for?
- Diagnosis of metastatic colorectal cancer to guide anti-EGFR therapy.
- Evaluation of advanced non-small cell lung cancer (NSCLC).
- Diagnosis and management of pancreatic ductal adenocarcinoma.
- Part of the molecular profiling for various solid tumors.
- When standard chemotherapy has failed, to identify targeted options.
- For patients being considered for clinical trials involving KRAS-targeted drugs.
How to prepare
- Consultation with an oncologist or genetic counselor to discuss the test's purpose.
- Provision of a formalin-fixed, paraffin-embedded (FFPE) tissue block or slides from a prior biopsy or surgery.
- If a new biopsy is needed, standard pre-biopsy preparations (like fasting) may apply.
- Informed consent process explaining the genetic nature of the test.
- Insurance pre-authorization may be required.
Risks & possible complications
- Risks are primarily associated with the tissue biopsy procedure (if a new sample is needed), such as bleeding, infection, or pain.
- Potential for an inconclusive result if the tissue sample has insufficient tumor DNA.
- Psychological impact of genetic information related to prognosis.
- Possible insurance or privacy concerns regarding genetic data (handled under strict confidentiality).
- No direct physical risks from the laboratory analysis itself.
Recovery & hospital stay
- Recovery is from the biopsy procedure, not the genetic test. Patients can typically resume normal activities shortly after a needle biopsy.
- Care for the biopsy site as instructed (e.g., keeping it clean and dry).
- Results are usually available within 7-14 business days and will be discussed in a follow-up appointment with the oncologist.
- The oncologist will explain the results and their implications for the treatment plan.
- No specific lifestyle changes are required post-analysis.
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Typical hospital stay: 0 days (outpatient for biopsy if needed)
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Expected recovery time: 0-2 days (from biopsy procedure)
Frequently Asked Questions
If you are considering kras mutation analysis in Turkey, these questions and answers can help you make a confident, informed decision.
Top-rated hospitals in Turkey with genetic medicine departments and experienced surgeons are ideal for this procedure. Use MediFyr to compare facilities, reviews, and doctor profiles before you decide.
Look at the doctor’s years of experience, hospital association, patient reviews, and how often they perform kras mutation analysis. MediFyr helps you compare genetic medicines and book consultations online.
The overall cost depends on hospital category, surgeon’s experience, room type, implant or device used (if any), length of stay, tests, and post-operative care. Our team can help you get cost estimates from multiple hospitals before you decide.
Procedure cost in other countries
Here is an overview of how the estimated cost, hospital stay, and recovery time for kras mutation analysis compare across other countries where we have data.
As a 72-year-old retired botanist with...
As a 72-year-old retired botanist with unexplained neurological decline, I was misdiagnosed for years until Dr. Grace Swarna Priya identified my rare ATXN2 gene mutation. Her personalized management plan at MIOT Hospital has slowed my progression remarkably, I can now enjoy gardening again with adapted tools.