About Intracytoplasmic Morphologically Selected Sperm Injection
Key Highlights
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Uses ultra-high magnification (over 6000x) to select sperm with optimal morphology and nuclear integrity.Improves selection of sperm with minimal DNA fragmentation, potentially leading to healthier embryos.Can increase fertilization rates and embryo quality compared to standard ICSI.Particularly beneficial for cases of severe male factor infertility or previous IVF failures.May reduce the risk of miscarriage and improve pregnancy outcomes.
Who is this surgery for?
- Severe male factor infertility (e.g., very low sperm count, poor motility, or abnormal morphology).
- Previous failed fertilization attempts with conventional IVF or ICSI.
- History of poor embryo quality in prior IVF cycles.
- High levels of sperm DNA fragmentation identified through testing.
- Recurrent pregnancy loss where male factor is suspected.
- Unexplained infertility where subtle sperm abnormalities may be a factor.
How to prepare
- Comprehensive fertility evaluation of both partners, including semen analysis and hormonal assessments.
- Female partner undergoes ovarian stimulation with fertility medications to produce multiple eggs.
- Monitoring via ultrasound and blood tests to track follicular development.
- Sperm sample collection from the male partner, typically on the day of the egg retrieval.
- Pre-procedure counseling to discuss the process, expectations, and potential outcomes.
- Informed consent for the IMSI procedure as part of the IVF cycle.
Risks & possible complications
- Similar to standard IVF/ICSI risks: ovarian hyperstimulation syndrome (OHSS), multiple pregnancies, and egg retrieval complications.
- No significant added procedural risk compared to ICSI, as it is a selection enhancement.
- Potential for no normal sperm to be identified, leading to cancellation of the injection step.
- Emotional and psychological stress associated with advanced fertility treatments.
- Financial cost, as IMSI is an add-on technique with additional charges.
Recovery & hospital stay
- Immediate recovery after egg retrieval is similar to standard IVF; rest is advised for the remainder of the day.
- Mild cramping or bloating may occur and typically resolves within a few days.
- Embryo transfer is usually performed 3-5 days after fertilization, requiring a brief clinic visit.
- Post-transfer, light activity is recommended; strenuous exercise should be avoided.
- A pregnancy test is scheduled approximately 10-14 days after the embryo transfer.
- Follow-up appointments are scheduled to monitor early pregnancy if the cycle is successful.
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Typical hospital stay: 0 days (outpatient procedure)
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Expected recovery time: 1-2 days (physical recovery from retrieval), 2 weeks (to pregnancy test)
Frequently Asked Questions
If you are considering intracytoplasmic morphologically selected sperm injection in Turkey, these questions and answers can help you make a confident, informed decision.
Top-rated hospitals in Turkey with ivf and reproductive medicine departments and experienced surgeons are ideal for this procedure. Use MediFyr to compare facilities, reviews, and doctor profiles before you decide.
Look at the doctor’s years of experience, hospital association, patient reviews, and how often they perform intracytoplasmic morphologically selected sperm injection. MediFyr helps you compare ivf and reproductive medicines and book consultations online.
The overall cost depends on hospital category, surgeon’s experience, room type, implant or device used (if any), length of stay, tests, and post-operative care. Our team can help you get cost estimates from multiple hospitals before you decide.
Procedure cost in other countries
Here is an overview of how the estimated cost, hospital stay, and recovery time for intracytoplasmic morphologically selected sperm injection compare across other countries where we have data.
| Country | Estimated cost range | Typical stay | Recovery time | View details |
|---|---|---|---|---|
| India | USD 2,719 – USD 4,895 | 0 days (outpatient procedure) | ~ 1-2 days (physical recovery from retrieval), 2 weeks (to pregnancy test) | Know More |
| Turkey | USD 20,131 – USD 36,236 | 0 days (outpatient procedure) | ~ 1-2 days (physical recovery from retrieval), 2 weeks (to pregnancy test) | Know More |
A 42-year-old corporate lawyer with premature...
A 42-year-old corporate lawyer with premature ovarian failure, previously told by three clinics that donor eggs were her only option. Dr. Mohan designed an aggressive but carefully monitored protocol with androgen priming and double stimulation. Against all odds, she produced two viable embryos and delivered healthy twins at 37 weeks via scheduled cesarean.