About Central Nervous System Lymphoma
Key Highlights
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Targeted treatment specifically designed to cross the protective blood-brain barrier.Multidisciplinary approach involving neuro-oncologists, radiation oncologists, and neurologists for comprehensive care.Utilizes high-dose chemotherapy protocols, such as methotrexate, which are effective against CNS lymphoma cells.Can incorporate advanced techniques like autologous stem cell transplant for eligible patients to allow for more aggressive therapy.Aims to achieve complete remission and improve survival rates while managing neurological symptoms.
Who is this surgery for?
- Diagnosis of primary CNS lymphoma (PCNSL), a lymphoma confined to the brain, eyes, or spinal cord.
- Secondary CNS lymphoma, where systemic lymphoma has spread to the central nervous system.
- Presence of neurological symptoms such as confusion, personality changes, seizures, weakness, or vision problems linked to lymphoma.
- Confirmation of lymphoma cells in the cerebrospinal fluid (CSF) via lumbar puncture.
- Radiographic evidence (MRI) of brain or spinal cord lesions suggestive of lymphoma, typically confirmed by biopsy.
How to prepare
- Comprehensive neurological examination and review of medical history by the oncologist.
- Diagnostic imaging, primarily MRI of the brain and/or spine with contrast.
- Stereotactic brain biopsy to obtain a definitive tissue diagnosis and guide treatment.
- Lumbar puncture to analyze cerebrospinal fluid for lymphoma cells.
- Baseline tests including complete blood count, kidney function tests (crucial for methotrexate), liver function tests, and HIV testing.
- Consultation with the treatment team to discuss the treatment plan, goals, and potential side effects.
Risks & possible complications
- Chemotherapy side effects: nausea, vomiting, hair loss, low blood cell counts (increasing infection risk), and kidney toxicity.
- Neurotoxicity from treatment, potentially causing confusion, memory issues, or leukoencephalopathy (brain tissue changes).
- Increased risk of infections, especially during periods of low white blood cell count.
- Potential for delayed cognitive decline or neurological deficits, particularly with combined chemotherapy and radiation.
- Complications related to the use of corticosteroids, such as high blood sugar, mood swings, and osteoporosis.
Recovery & hospital stay
- Initial recovery involves close monitoring in the hospital for side effects, especially after high-dose chemotherapy cycles.
- Regular follow-up MRI scans are essential to assess treatment response and monitor for recurrence.
- Ongoing management of side effects and supportive care, which may include medications, blood transfusions, or growth factors.
- Possible referral to physical, occupational, or speech therapy to address any neurological deficits.
- Long-term follow-up with the oncology team for surveillance, as CNS lymphoma has a risk of recurrence.
- Psychosocial support and counseling are often recommended for patients and caregivers.
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Typical hospital stay: Varies widely per treatment cycle; initial intensive phase may require 5-10 days per hospitalization.
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Expected recovery time: Several weeks to months for full recovery from a treatment cycle; long-term management is ongoing.
Frequently Asked Questions
If you are considering central nervous system lymphoma in India, these questions and answers can help you make a confident, informed decision.
Popular choices for central nervous system lymphoma in India include Manipal Hospital Old Airport Road, Kamineni Hospital LB Nagar, Cytecare Hospital, Kamineni Hospital, Tadigadapa, Miot Hospital Chennai, known for experienced specialists and advanced surgical infrastructure.
Look at the doctor’s years of experience, hospital association, patient reviews, and how often they perform central nervous system lymphoma. MediFyr helps you compare oncologists and book consultations online.
The overall cost depends on hospital category, surgeon’s experience, room type, implant or device used (if any), length of stay, tests, and post-operative care. Our team can help you get cost estimates from multiple hospitals before you decide.
Procedure cost in other countries
Here is an overview of how the estimated cost, hospital stay, and recovery time for central nervous system lymphoma compare across other countries where we have data.
| Country | Estimated cost range | Typical stay | Recovery time | View details |
|---|---|---|---|---|
| India | USD 3,807 – USD 13,052 | Varies widely per treatment cycle; initial intensive phase may require 5-10 days per hospitalization. | ~ Several weeks to months for full recovery from a treatment cycle; long-term management is ongoing. | Know More |
| Turkey | USD 28,184 – USD 96,630 | Varies widely per treatment cycle; initial intensive phase may require 5-10 days per hospitalization. | ~ Several weeks to months for full recovery from a treatment cycle; long-term management is ongoing. | Know More |
Top hospitals for Central Nervous System Lymphoma in India
These partner hospitals in India have dedicated oncologist teams and experience managing patients undergoing central nervous system lymphoma.
I'd been to a few doctors...
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Oncologists for Central Nervous System Lymphoma
Explore experienced oncologists who regularly perform central nervous system lymphoma and provide pre- and post-operative care in India.
- 13 Years Experience
- Surgical Oncologist
Manipal Hospital Dhakuria
- 12 Years Experience
- Oncologist
Manipal Hospital Varthur Road
- 9 Years Experience
- Oncologist
Manipal Hospitals Broadway
- 12 Years Experience
- Oncologist
Artemis Hospital Gurgaon
- 16 Years Experience
- Oncologist
Artemis Hospital Gurgaon
- 26 Years Experience
- Radiation Oncologist
SIMS Hospital Vadapalani
- 16 Years Experience
- Oncologist
Manipal Hospital Old Airport Road
- 14 Years Experience
- Oncologist
Manipal Hospitals Broadway
- 14 Years Experience
- Oncologist
Manipal Hospital Dhakuria