About Myelodysplastic Syndrome
Key Highlights
-
Personalized Treatment Plans: Care is tailored to the specific MDS subtype, risk category, and patient's overall health.Disease Management & Symptom Control: Aims to reduce transfusion dependency, manage fatigue and infections, and improve daily functioning.Potential to Delay Progression: Certain treatments can slow the progression of MDS to acute myeloid leukemia (AML).listrongCurative Potential for Some:/strong Allogeneic stem cell transplant offers a potential cure for eligible patients with higher-risk disease./lilistrongMultidisciplinary Approach:/strong Involves coordination with hematopathologists, transfusion medicine specialists, and transplant teams for comprehensive care./li/ul
Who is this surgery for?
- Unexplained and persistent low blood counts (cytopenias) such as anemia, neutropenia, or thrombocytopenia detected on routine blood tests.
- Presence of abnormal (dysplastic) blood cells or blasts in the peripheral blood smear.
- Symptoms related to low blood counts, including severe fatigue, shortness of breath, frequent infections, or easy bruising/bleeding.
- Diagnosis of a specific MDS subtype (e.g., MDS with single lineage dysplasia, MDS with excess blasts) confirmed by bone marrow biopsy.
- Determination of risk category (using IPSS-R scoring) to guide the intensity of therapy, ranging from observation to aggressive treatment.
How to prepare
- Comprehensive Diagnostic Workup: Preparation involves completing necessary blood tests, a bone marrow biopsy, and possibly genetic/chromosomal studies to confirm the diagnosis and subtype.
- Medical History & Physical Exam: A detailed review of all symptoms, past medical conditions, and medications is conducted.
- Risk Assessment & Staging: The oncologist uses results to calculate a prognostic score (IPSS-R) to determine the risk category and appropriate treatment path.
- Treatment Plan Discussion: Patient and family are counseled on the diagnosis, prognosis, and all potential treatment options, including benefits and risks.
- Pre-Treatment Optimization: For planned therapies like chemotherapy or transplant, pre-procedure steps may include dental clearance, heart/lung function tests, and managing any active infections.
Risks & possible complications
- Treatment-Specific Risks: Chemotherapy can cause nausea, hair loss, and increased risk of infections; growth factors may cause bone pain; immunosuppressive drugs increase infection risk.
- Disease Progression: Risk of transformation to acute myeloid leukemia (AML), especially in higher-risk MDS subtypes.
- Complications from Low Blood Counts: Severe anemia (fatigue, heart strain), neutropenia (life-threatening infections), and thrombocytopenia (serious bleeding).
- Stem Cell Transplant Risks: If pursued, includes graft-versus-host disease, organ toxicity, and high risk of severe infections during immune system recovery.
- Supportive Care Risks: Chronic blood transfusions can lead to iron overload, damaging the heart, liver, and endocrine organs.
Recovery & hospital stay
- Ongoing Monitoring: Recovery is a long-term process involving regular follow-up visits for blood tests to monitor counts and treatment response.
- Symptom Management: Managing fatigue, preventing infections through hygiene and sometimes prophylactic antibiotics, and addressing nutritional needs.
- Transfusion Support: For patients dependent on transfusions, regular outpatient visits for red blood cell or platelet transfusions are part of recovery.
- Medication Adherence: Strict adherence to prescribed medications (e.g., growth factors, chelation therapy for iron overload) is crucial.
- Post-Transplant Care: If a transplant is performed, recovery involves months of close monitoring for complications, immunosuppressive medications, and gradual immune reconstitution.
-
Typical hospital stay: Varies widely (Outpatient to 4-6 weeks+)
-
Expected recovery time: Ongoing/Long-term management
Frequently Asked Questions
If you are considering myelodysplastic syndrome in India, these questions and answers can help you make a confident, informed decision.
Popular choices for myelodysplastic syndrome in India include Kamineni Hospital LB Nagar, Cytecare Hospital, Kamineni Hospital, Tadigadapa, Miot Hospital Chennai, Manipal Hospital Old Airport Road, known for experienced specialists and advanced surgical infrastructure.
Look at the doctor’s years of experience, hospital association, patient reviews, and how often they perform myelodysplastic syndrome. MediFyr helps you compare oncologists and book consultations online.
The overall cost depends on hospital category, surgeon’s experience, room type, implant or device used (if any), length of stay, tests, and post-operative care. Our team can help you get cost estimates from multiple hospitals before you decide.
Procedure cost in other countries
Here is an overview of how the estimated cost, hospital stay, and recovery time for myelodysplastic syndrome compare across other countries where we have data.
Top hospitals for Myelodysplastic Syndrome in India
These partner hospitals in India have dedicated oncologist teams and experience managing patients undergoing myelodysplastic syndrome.
Sneha Davis, a 68-year-old retired librarian,...
Sneha Davis, a 68-year-old retired librarian, had always been active and independent. Over several months, she noticed increasing fatigue that made her afternoon walks impossible, and frequent, unexplained bruises appeared on her arms. Her primary care doctor found her blood counts were persistently low. Referred to an oncologist, Dr. Chen, a bone marrow biopsy confirmed a diagnosis of Myelodysplastic Syndrome (MDS). Dr. Chen explained that Sneha's higher-risk MDS required treatment to prevent progression to acute leukemia and recommended a course of Azacitidine, a chemotherapy drug given as subcutaneous injections. Sneha was terrified of the word 'chemotherapy' and the loss of control it implied. The treatment was taxing; she experienced nausea and profound fatigue after each weekly cycle. However, after four months, her blood counts began to stabilize. The bruises faded, and her energy slowly returned, allowing her to resume gardening. Emotionally, Sneha moved from a place of fear and resentment about her aging body to a cautious gratitude. The treatment gave her more time, and she found a new resilience, joining a patient support group to help others navigate their diagnosis.
Oncologists for Myelodysplastic Syndrome
Explore experienced oncologists who regularly perform myelodysplastic syndrome and provide pre- and post-operative care in India.
- 13 Years Experience
- Surgical Oncologist
KMC Hospital Mangalore, Mangalore
- 7 Years Experience
- Surgical Oncologist
Manipal Hospital Millers Road, Bangalore
- 13 Years Experience
- Oncologist
Manipal Hospital Millers Road, Bangalore
- 8 Years Experience
- Oncologist
KMC Hospital Mangalore, Mangalore
- 16 Years Experience
- Oncologist
Manipal Hospital Kanakapura Road, Bangalore
- 13 Years Experience
- Oncologist
Manipal Hospital Kanakapura Road, Bangalore
- 12 Years Experience
- Oncologist
Manipal Hospital Kanakapura Road, Bangalore
- 9 Years Experience
- Oncologist
Manipal Hospital Kanakapura Road, Bangalore
- 10 Years Experience
- Oncologist
Manipal Hospital Dhakuria, Kolkata
- 10 Years Experience
- Surgical Oncologist
Manipal Hospital Dhakuria, Kolkata
- 19 Years Experience
- Surgical Oncologist
Manipal Hospital Dhakuria, Kolkata
- 9 Years Experience
- Surgical Oncologist
Manipal Hospital Dhakuria, Kolkata
- 33 Years Experience
- Surgical Oncologist
Manipal Hospital Dhakuria, Kolkata
- 10 Years Experience
- Oncologist
Manipal Hospital Dhakuria, Kolkata
- 23 Years Experience
- Oncologist
Manipal Hospital Dhakuria, Kolkata
- 9 Years Experience
- Oncologist
Manipal Hospital Dhakuria, Kolkata
- 20 Years Experience
- Surgical Oncologist
Manipal Hospital Dhakuria, Kolkata
- 12 Years Experience
- Surgical Oncologist
Manipal Hospital Dhakuria, Kolkata
- 11 Years Experience
- Oncologist
Manipal Hospital Varthur Road, Bangalore
- 13 Years Experience
- Oncologist
Manipal Hospitals Broadway, Kolkata