Learn about Thalassemia Treatment in India — how it works, who it is for, recovery timelines, and what to expect before and after surgery. Compare hospitals and doctors experienced in Thalassemia and request assistance for cost estimates or appointments.

About Thalassemia

Bone Marrow Transplantation (BMT), also known as hematopoietic stem cell transplantation (HSCT), is a potentially curative treatment for severe forms of thalassemia, particularly beta-thalassemia major. This advanced procedure involves replacing a patient's diseased or defective bone marrow, which produces faulty red blood cells, with healthy, blood-forming stem cells from a compatible donor. These new stem cells then regenerate a healthy blood and immune system capable of producing normal hemoglobin. While it is a complex and intensive treatment requiring careful donor matching and significant medical support, a successful transplant can eliminate the need for lifelong blood transfusions and iron chelation therapy, offering patients a chance at a normal, transfusion-free life. It is considered the only definitive cure currently available for this inherited blood disorder.

Key Highlights

    Offers a potential cure for severe thalassemia, eliminating the need for lifelong transfusions.Can restore the body's ability to produce healthy, functional hemoglobin.Prevents long-term complications of iron overload from repeated transfusions.Improves overall quality of life and life expectancy for eligible patients.Utilizes advanced medical technology for precise donor matching and supportive care.

Who is this surgery for?

  • Patients diagnosed with beta-thalassemia major (Cooley's anemia) who are transfusion-dependent.
  • Individuals with severe thalassemia who have a matched sibling donor (ideal scenario).
  • Patients for whom matched unrelated donors or haploidentical (partially matched) donors are available, following rigorous evaluation.
  • Younger patients (often children or young adults) who are in good general health aside from their thalassemia.
  • Cases where iron overload has begun to cause organ damage despite chelation therapy.

How to prepare

  • Comprehensive evaluation including blood tests, imaging (heart, liver), and assessment of organ function.
  • Identification and HLA-typing of a suitable donor (sibling, unrelated registry, or family member).
  • Administration of conditioning therapy (chemotherapy +/- radiation) to destroy the existing bone marrow and suppress the immune system.
  • Central line placement (e.g., Hickman catheter) for administering medications, stem cells, and blood products.
  • Pre-transplant counseling for the patient and family regarding the process, risks, and recovery.
  • Preventive measures against infections, including protective isolation protocols.

Risks & possible complications

  • Graft-versus-host disease (GVHD), where donor immune cells attack the patient's body.
  • Graft failure, where the donor stem cells do not engraft and produce new blood cells.
  • Severe infections due to a weakened immune system during the neutropenic period.
  • Complications from the conditioning regimen, including organ damage (liver, lungs, heart).
  • Bleeding and anemia until the new marrow begins to function.
  • Long-term effects such as infertility, growth issues in children, or secondary cancers.

Recovery & hospital stay

  • Initial hospital stay in a sterile environment to prevent infection while blood counts recover.
  • Close monitoring for signs of engraftment (rising blood counts), GVHD, and infections.
  • Medications to prevent/treat GVHD (immunosuppressants) and prevent infections (antibiotics, antivirals).
  • Regular blood and platelet transfusions may be needed until the new marrow is fully functional.
  • Gradual reintroduction to a normal environment over several months with ongoing precautions.
  • Lifelong follow-up with the transplant team to monitor for late complications and ensure sustained graft function.
  • checked Typical hospital stay: 4-6 weeks
  • checked Expected recovery time: 6-12 months for full immune recovery

Frequently Asked Questions

If you are considering thalassemia in India, these questions and answers can help you make a confident, informed decision.

Procedure cost in other countries

Here is an overview of how the estimated cost, hospital stay, and recovery time for thalassemia compare across other countries where we have data.

Country Estimated cost range Typical stay Recovery time View details
India USD 16,315 – USD 38,069 4-6 weeks ~ 6-12 months for full immune recovery Know More
Turkey USD 120,788 – USD 281,838 4-6 weeks ~ 6-12 months for full immune recovery Know More

Top hospitals for Thalassemia in India

These partner hospitals in India have dedicated bone marrow transplantation teams and experience managing patients undergoing thalassemia.

Miot Hospital Chennai

  • IconChennai, India
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PATIENT REVIEW

Dr. chezhian subash provided exceptional care...

Dr. chezhian subash provided exceptional care for my bone marrow transplantation condition. The treatment was personalized and effective.

Bone Marrow Transplant Specialists for Thalassemia

Explore experienced bone marrow transplant specialists who regularly perform thalassemia and provide pre- and post-operative care in India.

Dr. Kishore Kumar
  • 12 Years Experience
  • Bone Marrow Transplant Specialist
Speaks: English, Tamil, Hindi
Next available on
02/Feb: 08:00 AM - 08:00 PM

MediFyr Plus Miot Hospital Chennai

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Dr. Chezhian Subash
  • 14 Years Experience
  • Bone Marrow Transplant Specialist
Speaks: English, Tamil, Hindi
Next available on
02/Feb: 08:00 AM - 08:00 PM

MediFyr Plus Miot Hospital Chennai

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Dr. Vinay Munikoty Venkatesh
  • 11 Years Experience
  • Bone Marrow Transplant Specialist
Speaks: English, Hindi
Next available on
02/Feb: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Yeshwanthpur

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Dr. Ashish Dixit
  • 25 Years Experience
  • Bone Marrow Transplant Specialist
Speaks: English, Hindi
Next available on
02/Feb: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Old Airport Road

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Dr. Lalit Kumar
  • 36 Years Experience
  • Bone Marrow Transplant Specialist
Speaks: English, Hindi
Next available on
02/Feb: 08:00 AM - 08:00 PM

MediFyr Plus Artemis Hospital Gurgaon

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Dr. Rahul Naithani
  • 21 Years Experience
  • Bone Marrow Transplant Specialist
Speaks: English, Hindi
Next available on
02/Feb: 08:00 AM - 08:00 PM

MediFyr Plus Artemis Hospital Gurgaon

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Dr. Rahul Sharma
  • 13 Years Experience
  • Bone Marrow Transplant Specialist
Speaks: English, Hindi
Next available on
02/Feb: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Jaipur

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Dr. Praveen Kumar Bansal
  • 32 Years Experience
  • Bone Marrow Transplant Specialist
Speaks: English, Hindi
Next available on
02/Feb: 08:00 AM - 08:00 PM

Metro Hospital Faridabad

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Dr. Sumant Gupta
  • 17 Years Experience
  • Bone Marrow Transplant Specialist
Speaks: English, Hindi
Next available on
02/Feb: 08:00 AM - 08:00 PM

Metro Hospital Noida Sector 11

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Dr. Sumant Gupta
  • 17 Years Experience
  • Bone Marrow Transplant Specialist
Speaks: English, Hindi
Next available on
02/Feb: 08:00 AM - 08:00 PM

Metro Hospital Noida Sector 11

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Dr. (Maj) A.P. Dubey
  • 14 Years Experience
  • Bone Marrow Transplant Specialist
Speaks: English, Hindi
Next available on
02/Feb: 08:00 AM - 08:00 PM

Metro Hospital Noida Sector 11

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Dr. Divya Bansal
  • 8 Years Experience
  • Bone Marrow Transplant Specialist
Speaks: English, Hindi
Next available on
02/Feb: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Dwarka

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Dr. Mahadeva Swamy B C
  • 11 Years Experience
  • Bone Marrow Transplant Specialist
Speaks: English, Hindi
Next available on
02/Feb: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Goa

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Dr. Utpal Chaudhuri
  • 16 Years Experience
  • Bone Marrow Transplant Specialist
Speaks: English, Hindi
Next available on
02/Feb: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Mukundapur

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Dr. Akshatha Nayak U
  • 14 Years Experience
  • Bone Marrow Transplant Specialist
Speaks: English, Hindi
Next available on
02/Feb: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospital Kanakapura Road

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Dr. Utpal Chaudhuri
  • 16 Years Experience
  • Bone Marrow Transplant Specialist
Speaks: English, Hindi
Next available on
02/Feb: 08:00 AM - 08:00 PM

MediFyr Plus Manipal Hospitals Broadway

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Dr. Sukriti Gupta
  • 12 Years Experience
  • Bone Marrow Transplant Specialist
Speaks: English, Hindi
Next available on
02/Feb: 08:00 AM - 08:00 PM

MediFyr Plus Artemis Hospital Gurgaon

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Dr. Gaurav Dixit
  • 11 Years Experience
  • Bone Marrow Transplant Specialist
Speaks: English, Hindi
Next available on
02/Feb: 08:00 AM - 08:00 PM

MediFyr Plus Artemis Hospital Gurgaon

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Dr. Anju Singh
  • 18 Years Experience
  • Bone Marrow Transplant Specialist
Speaks: English, Hindi
Next available on
02/Feb: 08:00 AM - 08:00 PM

MediFyr Plus Artemis Hospital Gurgaon

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